Kainic acid
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | Kainate agonist; excitant and neurotoxin |
Chemical Name: | (2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 213.23 |
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Citations for Kainic acid (35)
Citations are publications that use Bio-Techne products. Selected citations for Kainic acid include:
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Spitzer et al.
(2019)
Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age.
Neuron.
101:459
PMID: 30654924 -
Limó n et al.
(2019)
Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABAA receptors.
Transl Psychiatry.
9:218
PMID: 31488811 -
Morel et al.
(2018)
JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory.
J Neurosci.
38:3708
PMID: 29540552 -
Balleza-Tapia et al.
(2018)
TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro.
Elife.
7
PMID: 30417826 -
Evans
(2017)
Assembly, secretory pathway trafficking, and surface delivery of kainate receptors is regulated by neuronal activity.
Cell Rep.
19(12):2613
PMID: 28636947 -
Zhao
(2017)
Signaling by growth/differentiation factor 5 through the bone morphogenetic protein receptortype IB protects neurons against kainic acid-induced neurodegeneration.
Neurosci Lett.
651:36
PMID: 28458020 -
Fletcher
(2017)
Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy.
Nat Neurosci.
20(7):905
PMID: 28504671 -
Park et al.
(2016)
Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation.
Invest Ophthalmol Vis Sci.
57:508
PMID: 26868754 -
Smith et al.
(2016)
Superimposing Status Epilepticus on Neuron Subset-Specific PTEN Haploinsufficient and Wild Type Mice Results in Long-term Changes in Behavior.
Sci Rep.
6:36559
PMID: 27819284 -
Ferando and Mody
(2015)
In vitro gamma oscillations following partial and complete ablation of δ subunit-containing GABAA receptors from parvalbumin interneurons.
Neuropharmacology.
88:91
PMID: 25261782 -
Szokol et al.
(2015)
Augmentation of Ca(2+) signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy.
J Biol Chem.
9:49
PMID: 25762896 -
Xiao et al.
(2015)
CX3 chemokine receptor 1 deficiency leads to reduced dendritic complexity and delayed maturation of newborn neurons in the adult mouse hippocampus.
Front Cell Neurosci.
10:772
PMID: 26109952 -
Spampinato et al.
(2015)
Glial metabotropic glutamate receptor-4 increases maturation and survival of oligodendrocytes.
Neurotox Res.
8:462
PMID: 25642169 -
Parrish et al.
(2015)
Methionine increases BDNF DNA methylation and improves memory in epilepsy.
Neurobiol Dis.
2:401
PMID: 25909085 -
Chang et al.
(2014)
Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid.
Neurobiol Dis.
62:296
PMID: 24148856 -
Domin et al.
(2014)
Group III mGlu receptor agonist, ACPT-I, exerts potential neuroprotective effects in vitro and in vivo.
Ann Clin Transl Neurol.
26:99
PMID: 24402869 -
Neves et al.
(2013)
The LIM homeodomain protein Lhx6 regulates maturation of interneurons and network excitability in the mammalian cortex.
Cereb Cortex.
23:1811
PMID: 22710612 -
Ferando and Mody
(2013)
Altered gamma oscillations during pregnancy through loss of δ subunit-containing GABA(A) receptors on parvalbumin interneurons.
Front Neural Circuits.
7:144
PMID: 24062647 -
deCarvalho et al.
(2013)
Aversive cues fail to activate fos expression in the asymmetric olfactory-habenula pathway of zebrafish.
Front Neural Circuits.
7:98
PMID: 23734103 -
Bernard et al.
(2013)
Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures.
Nat Commun.
59:42736
PMID: 23831253 -
Krook-Magnuson et al.
(2013)
On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy.
J Neurosci.
4:1376
PMID: 23340416 -
Hou and Yu
(2013)
Activity-regulated somatostatin expression reduces dendritic spine density and lowers excitatory synaptic transmission via postsynaptic somatostatin receptor 4.
Neural Regen Res.
288:2501
PMID: 23233668 -
Rodriguez-Diaz et al.
(2012)
Real-time detection of acetylcholine release from the human endocrine pancreas.
Nat Protoc.
7:1015
PMID: 22555241 -
Huang et al.
(2012)
Glutamate may be an efferent transmitter that elicits inhibition in mouse taste buds.
PLoS One.
7:e30662
PMID: 22292013 -
Horita et al.
(2012)
Specialized motor-driven dusp1 expression in the song systems of multiple lineages of vocal learning birds.
PLoS One.
7:e42173
PMID: 22876306 -
Marrocco et al.
(2012)
Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus.
Proc Natl Acad Sci U S A.
32:17143
PMID: 23197707 -
Chuang et al.
(2012)
Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus.
J Neuroinflammation.
9:184
PMID: 22849356 -
Wang and Green
(2011)
Functional role of neurotrophin-3 in synapse regeneration by spiral ganglion neurons on inner hair cells after excitotoxic trauma in vitro.
J Neurosci.
31:7938
PMID: 21613508 -
Doyon et al.
(2011)
Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis.
J Neurosci.
7:e1002149
PMID: 21931544 -
Hitt et al.
(2010)
BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization.
Mol Neurodegener.
5:31
PMID: 20731874 -
Peng et al.
(2010)
Postsynaptic spiking homeostatically induces cell-autonomous regulation of inhibitory inputs via retrograde signaling.
J Neurosci.
30:16220
PMID: 21123568 -
Fritsch et al.
(2009)
Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis.
Neuroscience.
163:415
PMID: 19540312 -
Shin et al.
(2008)
Mislocalization of h channel subunits underlies h channelopathy in temporal lobe epilepsy.
Neurobiol Dis.
32:26
PMID: 18657617 -
Milstein et al.
(2007)
TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating.
Neuron.
55:905
PMID: 17880894 -
Elliott-Hunt et al.
(2004)
Galanin acts as a neuroprotective factor to the hippocampus.
PLoS Comput Biol.
101:5105
PMID: 15041741
There are no citations that match your criteria.