NBQX

Tocris Bioscience, part of Bio-Techne | Catalog # 0373

Potent AMPA antagonist; more selective than CNQX (Cat. No. 0190)
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Key Product Details

Description

Potent AMPA antagonist; more selective than CNQX (Cat. No. 0190)

View all AMPA Receptor Antagonists »

Product Description

NBQX is a selective and competitive AMPA and kainate receptor antagonist (IC50 = 0.15 μM and 4.8 μM, respectively). NBQX blocks the antidepressant effects of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529), decreases mTOR and BDNF levels. NBQX is neuroprotective, anticonvulsant, antinociceptive and active in vivo.

NBQX disodium salt, a more water-soluble form of NBQX, also available.

Licensing Information

Sold with the permission of Novo Nordisk A/S

Product Specifications

Molecular Weight

336.28

Formula

C12H8N4O6S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide

CAS Number

118876-58-7

PubChem ID

3272524

InChI Key

UQNAFPHGVPVTAL-UHFFFAOYSA-N

SMILES

NS(=O)(=O)C1=CC=CC2=C3NC(=O)C(=O)NC3=CC(=C12)[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.63 100

Preparing Stock Solutions for NBQX

The following data is based on the product molecular weight 336.28

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.97 mL 14.87 mL 29.74 mL
5 mM 0.59 mL 2.97 mL 5.95 mL
10 mM 0.30 mL 1.49 mL 2.97 mL
50 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

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Reconstitution Calculator

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Product Documents for NBQX

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NBQX

For research use only

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