Mouse IL‑1 beta/IL‑1F2 Antibody Best Seller

Name: Mouse IL‑1 beta/IL‑1F2 Antibody
Brand: R&D Systems
SKU: AF-401-NA
Rating: 4 (24 reviews)

Catalog # AF-401-NA | R&D Systems, Inc. a Bio-Techne Brand

(24)

Citations (269)

Product Datasheet / COA / SDS

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Product Summary
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Mouse

Applications

Immunocytochemistry, Immunohistochemistry, Neutralization, Simple Western, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Product Summary for Mouse IL‑1 beta/IL‑1F2 Antibody

Immunogen

E. coli-derived recombinant mouse IL-1 beta/IL-1F2
Val118-Ser269
Accession # NP_032387

Specificity

Detects mouse IL-1 beta/IL-1F2 in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Mouse IL‑1 beta/IL‑1F2 Antibody

Detection of Human and Mouse IL‑1 beta/IL‑1F2 by Western Blot.

Western blot shows lysates of THP-1 human acute monocytic leukemia cell line untreated (-) or treated (+) with 200 nM PMA for 24 hours and 10 µg/mL LPS for 4 hours and RAW 264.7 mouse monocyte/macrophage cell line untreated (-) or treated (+) with 10 µg/mL LPS for 24 hours. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Mouse IL-1 beta/IL-1F2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-401-NA) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for IL-1 beta/IL-1F2 at approximately 35 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

IL‑1 beta/IL‑1F2 in MCF‑7 Human Cell Line.

IL-1 beta/IL-1F2 was detected in immersion fixed MCF-7 human breast cancer cell line using Goat Anti-Mouse IL-1 beta/IL-1F2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-401-NA) at 8 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

IL‑1 beta/IL‑1F2 in Mouse Thymus.

IL-1 beta/IL-1F2 was detected in perfusion fixed frozen sections of mouse thymus using Goat Anti-Mouse IL-1 beta/IL-1F2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-401-NA) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Detection of Mouse IL‑1 beta/IL‑1F2 by Simple Western^TM.

Simple Western lane view shows lysates of RAW 264.7 mouse monocyte/macrophage cell line untreated (-) or treated (+) with 10 µg/mL LPS for 24 hours, loaded at 0.5 mg/mL. A specific band was detected for IL-1 beta/IL-1F2 at approximately 40 kDa (as indicated) using 2.5 µg/mL of Goat Anti-Mouse IL-1 beta/IL-1F2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-401-NA) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Cell Proliferation Induced by IL‑1 beta/IL‑1F2 and Neutralization by Mouse IL-1 beta/IL-1F2 Antibody.

Recombinant Mouse IL-1 beta/IL-1F2 (401-ML) stimulates proliferation in the the D10.G4.1 mouse helper T cell line in a dose-dependent manner (orange line) as measured by Resazurin (AR002). Proliferation elicited by Recombinant Mouse IL-1 beta/IL-1F2 (50 pg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse IL-1 beta/IL-1F2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-401-NA). The ND₅₀ is typically ≤ 0.25 µg/mL.

Detection of IL‑1 beta/IL‑1F2 in Mouse Intestine.

IL‑1 beta/IL‑1F2 was detected in perfusion fixed paraffin-embedded sections of Mouse Intestine using Goat Anti-Mouse IL‑1 beta/IL‑1F2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-401-NA) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Sheep IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC006). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in epithelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

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Applications for Mouse IL‑1 beta/IL‑1F2 Antibody

Application

Recommended Usage

Immunocytochemistry

5-15 µg/mL
Sample: Immersion fixed mouse T cells and immersion fixed MCF-7 human breast cancer cell line

Immunohistochemistry

5-15 µg/mL
Sample: Perfusion fixed frozen Mouse Thymus and perfusion fixed paraffin-embedded sections of Mouse Intestine.

Simple Western

2.5 µg/mL
Sample: RAW 264.7 mouse monocyte/macrophage cell line treated with LPS

Western Blot

0.25 µg/mL
Sample: THP‑1 human acute monocytic leukemia cell line treated with PMA and LPS and RAW 264.7 mouse monocyte/macrophage cell line treated with LPS

Neutralization

Measured by its ability to neutralize IL‑1 beta/IL‑1F2-induced proliferation in the D10.G4.1 mouse helper T cell line. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The Neutralization Dose (ND₅₀) is typically ≤0.25 µg/mL in the presence of 50 pg/mL Recombinant Mouse IL‑1 beta/IL‑1F2.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 24 reviews rated 4.1 using AF-401-NA in the following applications:

Block/Neutralize (1 Review)
ELISA (3 Reviews)
Flow Cytometry (3 Reviews)
Immunocytochemistry (1 Review)
Immunocytochemistry/Immunofluorescence (1 Review)
Immunohistochemistry (2 Reviews)
Simple Western (1 Review)
Western Blot (12 Reviews)

Formulation, Preparation and Storage

Purification

Antigen Affinity-purified

Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-1 beta/IL-1F2

IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2, IL1B), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 17% amino acid (aa) identity in mouse. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL-1 alpha and IL-1 beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1 RI binds directly to IL-1 alpha or IL-1 beta and then associates with IL-1 R accessory protein (IL-1 R3/IL-1 R AcP) to form a high-affinity receptor complex that is competent for signal transduction. IL-1 RII has high affinity for IL-1 beta but functions as a decoy receptor and negative regulator of IL-1 beta activity. IL-1ra functions as a competitive antagonist by preventing IL-1 alpha and IL-1 beta from interacting with IL-1 RI. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. The 17 kDa molecular weight mature mouse IL-1 beta shares 90% aa sequence identity with cotton rat and rat and 67%-78% with canine, equine, feline, human, porcine, and rhesus macaque IL-1 beta. IL-1 beta functions in a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases.

Long Name

Interleukin 1 beta

Alternate Names

IL-1b, IL-1F2, IL1 beta, IL1B

Entrez Gene IDs

403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig); 3553 (Human); 16176 (Mouse); 397122 (Porcine); 24494 (Rat)

Gene Symbol

IL1B

UniProt

NP_032387

Product Documents for Mouse IL‑1 beta/IL‑1F2 Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Mouse IL‑1 beta/IL‑1F2 Antibody

For research use only

Citations
Reviews

Citations for Mouse IL‑1 beta/IL‑1F2 Antibody (269)

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Citations are publications that use Bio-Techne products. Selected citations for Mouse IL‑1 beta/IL‑1F2 Antibody include:

Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

TT Lin et al. (2023-09-01), Suppressing high mobility group box-1 release alleviates morphine tolerance via the adenosine 5'-monophosphate-activated protein kinase/heme oxygenase-1 pathway Neural regeneration research, 2023-018(9):2067-2074.
PMID: 36926733
Species: Mouse
Sample Types: Cell Lysates
Applications: Bioassay

Liu et al. (2023-06-01), Parthenolide targets NLRP3 to treat inflammasome-related diseases International immunopharmacology
PMID: 37167640
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Weerasinghe et al. (2023-05-18), Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response Cell reports
PMID: 37204928
Species: Mouse,Transgenic Mouse
Sample Types: Cell Lysates,Cell Culture Supernates
Applications: Western Blot

Ren et al. (2023-05-12), Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis International immunopharmacology
PMID: 37182452
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Zhang et al. (2023-05-12), Pirfenidone Inhibits Alveolar Bone Loss in Ligature-Induced Periodontitis by Suppressing the NF-?B Signaling Pathway in Mice International journal of molecular sciences
PMID: 37240020
Species: Mouse
Sample Types: Cell Culture Supernates

Huang et al. (2023-05-09), Endosomal trafficking of two-pore K+ efflux channel TWIK2 to plasmalemma mediates NLRP3 inflammasome activation and inflammatory injury eLife
PMID: 37158595
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Siopi et al. (2023-05-02), Gut microbiota changes require vagus nerve integrity to promote depressive-like behaviors in mice Molecular psychiatry
PMID: 37131071
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

A Ta et al. (2023-04-11), A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3 Nature Communications, 2023-014(1):2035.
PMID: 37041208
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

S Bollenbeck et al. (2023-03-25), Phosphate induces inflammation and exacerbates injury from cigarette smoke in the bronchial epithelium Scientific Reports, 2023-013(1):4898.
PMID: 36966182
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

JH Kang et al. (2023-03-23), Novel Activity of ODZ10117, a STAT3 Inhibitor, for Regulation of NLRP3 Inflammasome Activation International Journal of Molecular Sciences, 2023-024(7).
PMID: 37047051
Species: Mouse
Sample Types: Whole Tissue,Tissue Homogenates,Whole Cells
Applications: ICC,IHC,Western Blot

J Li et al. (2023-03-17), HIF1alpha-BNIP3-mediated mitophagy protects against renal fibrosis by decreasing ROS and inhibiting activation of the NLRP3 inflammasome Cell Death & Disease, 2023-014(3):200.
PMID: 36928344
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

A Hooftman et al. (2023-03-08), Macrophage fumarate hydratase restrains mtRNA-mediated interferon production Nature, 2023-0615(7952):490-498.
PMID: 36890227
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

WJ Zhong et al. (2023-03-06), TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury Journal of Translational Medicine, 2023-021(1):179.
PMID: 36879273
Species: Mouse
Sample Types: Protein Lysates
Applications: Western Blot

Y Chen et al. (2023-03-01), Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model Investigative Ophthalmology & Visual Science, 2023-064(3):26.
PMID: 36920364
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Y Wang et al. (2023-02-18), Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-kappaB pathway in LPC-induced demyelination Journal of Neuroinflammation, 2023-020(1):41.
PMID: 36803990
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

X Shu et al. (2023-02-16), Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome Cell Reports, 2023-042(2):112133.
PMID: 36800288
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

A Filippini et al. (2023-02-06), LRRK2 Kinase Inhibition Attenuates Astrocytic Activation in Response to Amyloid beta1-42 Fibrils Biomolecules, 2023-013(2).
PMID: 36830676
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

MB Reynolds et al. (2023-02-03), Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation Science Advances, 2023-09(5):eade8701.
PMID: 36735777
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

G Lin et al. (2023-02-02), Carnosic acid inhibits NLRP3 inflammasome activation by targeting both priming and assembly steps International immunopharmacology, 2023-0116(0):109819.
PMID: 36738671
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

A Ramadan et al. (2023-02-01), The NLRP3 Inflammasome Is Required for Protection Against Pseudomonas Keratitis Investigative Ophthalmology & Visual Science, 2023-064(2):11.
PMID: 36749596
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

L González-C et al. (2023-01-14), Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors Bioorganic chemistry, 2023-0132(0):106362.
PMID: 36657273
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

HW Xu et al. (2023-01-10), Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice Acta pharmacologica Sinica, 2023-00(0).
PMID: 36627344
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

G Lee et al. (2022-12-28), JC2-11, a benzylideneacetophenone derivative, attenuates inflammasome activation Scientific Reports, 2022-112(1):22484.
PMID: 36577816
Species: Mouse
Sample Types: Tissue Lysates
Applications: Western Blot

SK Juin et al. (2022-12-15), Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes Scientific Reports, 2022-112(1):21707.
PMID: 36522378
Species: Mouse
Sample Types: Cell Culture Supernates

LM Branco et al. (2022-12-08), Lysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1beta secretion Cell Death & Disease, 2022-113(12):1029.
PMID: 36481780
Species: Transgenic Mouse,Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

C Oh et al. (2022-11-22), Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins Cell Reports, 2022-141(8):111688.
PMID: 36417874
Species: Transgenic Mouse
Sample Types: Cell Lysates
Applications: Western Blot

YH Wu et al. (2022-11-11), Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells Science Advances, 2022-18(45):eabn9912.
PMID: 36367942
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

MSJ Mangan et al. (2022-11-07), Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever PloS Biology, 2022-120(11):e3001351.
PMID: 36342970
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

SL Kim et al. (2022-10-20), Lipocalin 2 activates the NLRP3 inflammasome via LPS?induced NF?kappaB signaling and plays a role as a pro?inflammatory regulator in murine macrophages Molecular Medicine Reports, 2022-126(6).
PMID: 36263611
Species: Mouse
Sample Types: Tissue Homoegenates
Applications: Western Blot

P Sharma et al. (2022-09-29), HDAC5 RNA interference ameliorates acute renal injury by upregulating KLF2 and inhibiting NALP3 expression in a mouse model of oxalate nephropathy International immunopharmacology, 2022-0112(0):109264.
PMID: 36183679
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

M Duhalde Ve et al. (2022-09-21), PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical beta-coronavirus disease Science Advances, 2022-08(38):eabn6545.
PMID: 36129987
Species: Mouse
Sample Types: Protein Lysates
Applications: Western Blot

AA Abdelrahma et al. (2022-09-16), Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy Cells, 2022-011(18).
PMID: 36139465
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

I de Castro et al. (2022-09-15), Neutrophil-mediated fibroblast-tumor cell il-6/stat-3 signaling underlies the association between neutrophil-to-lymphocyte ratio dynamics and chemotherapy response in localized pancreatic cancer: A hybrid clinical-preclinical study Elife, 2022-011(0).
PMID: 36107485
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Y Zhu et al. (2022-09-14), FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system Cell Death and Differentiation, 2022-00(0).
PMID: 36104448
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Q Lin et al. (2022-09-14), Identification of lncRNA DLEU2 as a potential diagnostic biomarker and anti-inflammatory target for ulcerative colitis Frontiers in Pharmacology, 2022-013(0):991448.
PMID: 36188540
Species: Mouse
Sample Types: Serum
Applications: Western Blot

SM Ruwanpura et al. (2022-08-29), Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1beta axes bridge innate immunity and epithelial apoptosis to promote emphysema Proceedings of the National Academy of Sciences of the United States of America, 2022-0119(36):e2201494119.
PMID: 36037355
Species: Rabbit
Sample Types: Whole Tissue
Applications: IHC

H Shi et al. (2022-08-05), An injectable thermosensitive hydrogel for dual delivery of diclofenac and Avastinï¿½ to effectively suppress inflammatory corneal neovascularization International journal of pharmaceutics, 2022-00(0):122081.
PMID: 35934166
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

AQ Dong et al. (2022-07-27), Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson's disease Acta pharmacologica Sinica, 2022-00(0).
PMID: 35896696
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

AB Lopez-Rodr et al. (2022-07-26), Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma Pharmaceutics, 2022-014(8).
PMID: 35893807
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

JH Ma et al. (2022-07-20), Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model EBioMedicine, 2022-082(0):104184.
PMID: 35870427
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

W Chen et al. (2022-07-06), Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion Nature Immunology, 2022-023(7):1021-1030.
PMID: 35794369
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

W Yu et al. (2022-06-21), Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters Nature Communications, 2022-013(1):3544.
PMID: 35729093
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Y Jin et al. (2022-05-31), Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis Cell Death & Disease, 2022-013(5):512.
PMID: 35641492
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Q Zhang et al. (2022-05-03), TH17 cells promote CNS inflammation by sensing danger signals via Mincle Nature Communications, 2022-013(1):2406.
PMID: 35504893
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

LK Billingham et al. (2022-04-28), Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation Nature Immunology, 2022-00(0).
PMID: 35484407
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

ES Jung et al. (2022-04-27), Amyloid-beta activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk-AMPK pathway Aging Cell, 2022-00(0):e13623.
PMID: 35474599
Species: Mouse
Sample Types: Tissue Lysates
Applications: Western Blot

L Zhou et al. (2022-04-13), Farrerol Alleviates Myocardial Ischemia/Reperfusion Injury by Targeting Macrophages and NLRP3 Frontiers in Pharmacology, 2022-013(0):879232.
PMID: 35496295
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

F Li et al. (2022-03-21), BMAL1 regulates Propionibacterium acnes-induced skin inflammation via REV-ERBalpha in mice International journal of biological sciences, 2022-018(6):2597-2608.
PMID: 35414779
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

K Molnár et al. (2022-03-19), Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury Journal of Neuroinflammation, 2022-019(1):68.
PMID: 35305649
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA

CMA Rego et al. (2022-03-18), Inflammasome NLRP3 activation induced by Convulxin, a C-type lectin-like isolated from Crotalus durissus terrificus snake venom Scientific Reports, 2022-012(1):4706.
PMID: 35304541
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

B Czaya et al. (2022-03-18), Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling Elife, 2022-011(0).
PMID: 35302487
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

MF Mohamed et al. (2022-03-11), CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT Nature Communications, 2022-013(1):1295.
PMID: 35277504
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

K Eislmayr et al. (2022-03-02), Nonredundancy of IL-1alpha and IL-1beta is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection Science Advances, 2022-08(9):eabj7293.
PMID: 35235356
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

YT Wang et al. (2022-02-22), K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy Cell Reports, 2022-038(8):110354.
PMID: 35196483
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Y Jiao et al. (2022-02-11), Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis European Journal of Medicinal Chemistry, 2022-0232(0):114194.
PMID: 35183871
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

T Xu et al. (2022-02-02), Ubiquitination of NLRP3 by gp78/Insig-1 restrains NLRP3 inflammasome activation Cell Death and Differentiation, 2022-00(0).
PMID: 35110683
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

K Tóth et al. (2022-01-27), The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner PloS Biology, 2022-020(1):e3001526.
PMID: 35085235
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Murthy et al. (2022-01-24), TREM-1 is required for enhanced OpZ-induced superoxide generation following priming Journal of leukocyte biology, 2022-00(0).
PMID: 35075692
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

D Szabó et al. (2022-01-20), Maternal P2X7 receptor inhibition prevents autism-like phenotype in male mouse offspring through the NLRP3-IL-1beta pathway Brain, Behavior, and Immunity, 2022-00(0).
PMID: 35065198
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Wang et al. (2022-01-12), Activation of Transcription Factor EB Alleviates Tubular Epithelial Cell Injury via Restoring Lysosomal Homeostasis in Diabetic Nephropathy Oxidative Medicine and Cellular Longevity, 2022-02022(0):2812493.
PMID: 35082964
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

MA Munoz et al. (2021-12-30), Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages Elife, 2021-110(0).
PMID: 34967731
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

NC Williams et al. (2021-12-17), Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1alpha in lipopolysaccharide-activated macrophages The Journal of Biological Chemistry, 2021-10(0):101501.
PMID: 34929172
Species: Mouse
Sample Types: Whole Tissue,Tissue Homogenates
Applications: Western Blot,IHC

K Yuan et al. (2021-12-11), Sensory nerves promote corneal inflammation resolution via CGRP mediated transformation of macrophages to the M2 phenotype through the PI3K/AKT signaling pathway International immunopharmacology, 2021-1102(0):108426.
PMID: 34906854
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Z Wei et al. (2021-10-14), Dihydrotanshinone I Specifically Inhibits NLRP3 Inflammasome Activation and Protects Against Septic Shock In Vivo Frontiers in Pharmacology, 2021-112(0):750815.
PMID: 34721038
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

H Ahn et al. (2021-09-30), Parabens disrupt non-canonical inflammasome activation International immunopharmacology, 2021-0101(0):108196.
PMID: 34601332
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

B Wen et al. (2021-09-22), Antiatherosclerotic effect of dehydrocorydaline on ApoE-/- mice: inhibition of macrophage inflammation Acta pharmacologica Sinica, 2021-00(0).
PMID: 34552216
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Jiang et al. (2021-09-21), Proteopathic tau primes and activates interleukin-1beta via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway Cell Reports, 2021-036(12):109720.
PMID: 34551296
Species: Rat
Sample Types: In Vivo
Applications: Neutralization

Y Tang et al. (2021-09-20), Chronic colitis upregulates microRNAs suppressing brain-derived neurotrophic factor in the adult heart PLoS ONE, 2021-016(9):e0257280.
PMID: 34543287
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

P Chen et al. (2021-09-16), The Essential Oil of Artemisia argyi H.Lï¿½v. and Vaniot Attenuates NLRP3 Inflammasome Activation in THP-1 Cells Frontiers in Pharmacology, 2021-012(0):712907.
PMID: 34603026
Species: Mouse
Sample Types: Cell Lysates,Whole Cells
Applications: ICC,ChIP,Western Blot

X Li et al. (2021-08-24), Macrophage HIF-2alpha suppresses NLRP3 inflammasome activation and alleviates insulin resistance Cell Reports, 2021-036(8):109607.
PMID: 34433035
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

D Reimers et al. (2021-08-13), Immunohistochemical Study of ASC Expression and Distribution in the Hippocampus of an Aged Murine Model of Alzheimer's Disease International Journal of Molecular Sciences, 2021-022(16).
PMID: 34445402
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

P Ortiz-Rome et al. (2021-08-03), Co-Treatment With Verapamil and Curcumin Attenuates the Behavioral Alterations Observed in Williams-Beuren Syndrome Mice by Regulation of MAPK Pathway and Microglia Overexpression Frontiers in Pharmacology, 2021-012(0):670785.
PMID: 34413771
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

XY Wu et al. (2021-08-02), ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome Acta pharmacologica Sinica, 2021-00(0).
PMID: 34341510
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Rastogi et al. (2021-07-29), Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF PloS Pathogens, 2021-017(7):e1009712.
PMID: 34324582
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Nizami et al. (2021-07-28), A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation Scientific Reports, 2021-011(1):15319.
PMID: 34321581
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

H Ahn et al. (2021-07-02), NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation Cells, 2021-010(7).
PMID: 34359830
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

CC Lin et al. (2021-06-29), Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation Nature Communications, 2021-012(1):3878.
PMID: 34188032
Species: Human
Sample Types: Transfected Whole Cells
Applications: Neutralization

B Ratitong et al. (2021-05-18), &beta-Glucan-stimulated neutrophil secretion of IL-1&alpha is independent of GSDMD and mediated through extracellular vesicles Cell Reports, 2021-035(7):109139.
PMID: 34010648
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

SL Vijayaraj et al. (2021-05-11), The ubiquitylation of IL-1&beta limits its cleavage by caspase-1 and targets it for proteasomal degradation Nature Communications, 2021-012(1):2713.
PMID: 33976225
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Xia et al. (2021-04-21), Gasdermin D pore structure reveals preferential release of mature interleukin-1 Nature, 2021-00(0).
PMID: 33883744
Species: Mouse
Sample Types: Whole Cells,Cell Lysates
Applications: Western Blot,Proximity Ligation Assay,Flow Cytometry

X Wang et al. (2021-04-14), A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis Cell Death & Disease, 2021-012(4):402.
PMID: 33854044
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

B Zhou et al. (2021-04-13), Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases Cell Reports, 2021-035(2):108998.
PMID: 33852854
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Z Li et al. (2021-04-08), Vaccine delivery alerts innate immune systems for more immunogenic vaccination JCI Insight, 2021-00(0).
PMID: 33690222
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

C Zhang et al. (2021-04-01), Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities European Journal of Medicinal Chemistry, 2021-0219(0):113417.
PMID: 33845232
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

A Shimada et al. (2021-03-10), Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice Toxicology reports, 2021-08(0):520-528.
PMID: 33747797
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

MN Lee et al. (2021-03-08), Luteolin inhibits NLRP3 inflammasome activation via blocking ASC oligomerization The Journal of nutritional biochemistry, 2021-00(0):108614.
PMID: 33705947
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Y Mishima et al. (2021-02-25), Sex-dependent differences in the gut microbiota following chronic nasal inflammation in adult mice Scientific Reports, 2021-011(1):4640.
PMID: 33633180
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

J Li et al. (2021-02-12), Omega-3FAs Can Inhibit the Inflammation and Insulin Resistance of Adipose Tissue Caused by HHcy Induced Lipids Profile Changing in Mice Frontiers in Physiology, 2021-012(0):628122.
PMID: 33643070
Species: Mouse
Sample Types: Cell Lysates,Whole Cells
Applications: Western Blot,ICC

Y Shi et al. (2021-01-25), NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages International immunopharmacology, 2021-092(0):107358.
PMID: 33508701
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

S Estfanous et al. (2021-01-13), Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo Scientific Reports, 2021-011(1):855.
PMID: 33441602
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Q Lin et al. (2020-12-19), Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy Autophagy, 2020-10(0):1-16.
PMID: 33345685
Species: Mouse
Sample Types: Tissue Lysates
Applications: Western Blot

J Nilsson et al. (2020-12-11), NKT cells promote both type 1 and type 2 inflammatory responses in a mouse model of liver fibrosis Scientific Reports, 2020-110(1):21778.
PMID: 33311540
Species: Human
Sample Types: Cell Culture Supernates
Applications: Western Blot

W Wang et al. (2020-11-26), Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome BMC Biol, 2020-118(1):182.
PMID: 33243234
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

B Nógrádi et al. (2020-11-26), Upregulation of Nucleotide-Binding Oligomerization Domain-, LRR- and Pyrin Domain-Containing Protein 3 in Motoneurons Following Peripheral Nerve Injury in Mice Frontiers in Pharmacology, 2020-111(0):584184.
PMID: 33328988
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

DR Sweet et al. (2020-11-18), Myeloid Krï¿½ppel-like factor 2 is a critical regulator of metabolic inflammation Nat Commun, 2020-111(1):5872.
PMID: 33208733
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

R Kajino-Sak et al. (2020-11-12), Synthetic lethality between MyD88 loss and mutations in Wnt/&beta-catenin pathway in intestinal tumor epithelial cells Oncogene, 2020-10(0).
PMID: 33177648
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

H Ahn et al. (2020-11-05), Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity Sci Rep, 2020-110(1):19091.
PMID: 33154451
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

T Matsuoka et al. (2020-10-21), Inhibition of NLRP3 inflammasome by MCC950 improves the metabolic outcome of islet transplantation by suppressing IL-1&beta and islet cellular death Sci Rep, 2020-110(1):17920.
PMID: 33087823
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

YH Kim et al. (2020-10-05), Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion Autophagy, 2020-10(0):1-18.
PMID: 33017561
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot,Immunoprecipitation

Q Zhao et al. (2020-09-28), Pristimerin protects against inflammation and metabolic disorder in mice through inhibition of NLRP3 inflammasome activation Acta Pharmacol Sin, 2020-00(0).
PMID: 32989235
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

A Volchuk et al. (2020-09-11), Indirect regulation of HMGB1 release by gasdermin D Nat Commun, 2020-011(1):4561.
PMID: 32917873
Species: Mouse,Human
Sample Types: Cell Culture Supernates,Cell Lysates
Applications: Western Blot

TM Tucey et al. (2020-08-04), Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection PLoS Pathog., 2020-016(8):e1008695.
PMID: 32750090
Species: Human
Sample Types: Whole Cells
Applications: IP

K Bulek et al. (2020-08-03), Epithelial-derived gasdermin D mediates nonlytic IL-1&beta release during experimental colitis J. Clin. Invest., 2020-00(0).
PMID: 32597834
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

KM von Herrma et al. (2020-07-17), Slc6a3-dependent expression of a CAPS-associated Nlrp3 allele results in progressive behavioral abnormalities and neuroinflammation in aging mice J Neuroinflammation, 2020-017(1):213.
PMID: 32680528
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot,Immunoprecipitation

S Xiong et al. (2020-07-01), IL-1beta suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury J. Clin. Invest., 2020-0130(7):3684-3698.
PMID: 32298238
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

YH Park et al. (2020-06-29), Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis Nat. Immunol., 2020-00(0).
PMID: 32601469
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Huang et al. (2020-05-04), Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity Nat. Cell Biol., 2020-00(0).
PMID: 32367047
Species: Mouse
Sample Types: Whole Cells
Applications: Western Blot

CA Donado et al. (2020-04-07), A Two-Cell Model for IL-1&beta Release Mediated by Death-Receptor Signaling Cell Rep, 2020-031(1):107466.
PMID: 32268091
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Y Wang et al. (2020-04-06), ELMO2 association with G&alphai2 regulates pancreatic cancer cell chemotaxis and metastasis PeerJ, 2020-08(0):e8910.
PMID: 32292657
Species: Mouse
Sample Types: Cell Culture Lysates
Applications: Western Blot

S Hamarsheh et al. (2020-04-03), Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation Nat Commun, 2020-011(1):1659.
PMID: 32246016
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Q Li et al. (2020-04-01), Inhibition of double-strand DNA-sensing cGAS ameliorates brain injury after ischemic stroke EMBO Mol Med, 2020-012(4):e11002.
PMID: 32239625
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

BR Kim et al. (2020-03-25), Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress PLoS Pathog., 2020-016(3):e1008294.
PMID: 32210476
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

H Tozaki-Sai et al. (2020-03-21), Involvement of exchange protein directly activated by cAMP and tumor progression locus 2 in IL-1&beta production in microglial cells following activation of &beta-adrenergic receptors J. Pharmacol. Sci., 2020-00(0).
PMID: 32253104
Species: Mouse
Sample Types: Tissue Lysates
Applications: Western Blot

F Cao et al. (2020-03-19), Suppression of NLRP3 Inflammasome by Erythropoietin via the EPOR/JAK2/STAT3 Pathway Contributes to Attenuation of Acute Lung Injury in Mice Front Pharmacol, 2020-011(0):306.
PMID: 32265704
Species: Mouse
Sample Types: Cell Culture Lysates
Applications: Western Blot

R Nakata et al. (2020-03-17), Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene Sci Rep, 2020-010(1):4883.
PMID: 32184453
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

S Subbarao et al. (2020-02-28), Genetic and pharmacological inhibition of inflammasomes reduces the survival of Mycobacterium tuberculosis strains in macrophages Sci Rep, 2020-010(1):3709.
PMID: 32111888
Species: Human
Sample Types: Cell Culture Lysates
Applications: Western Blot

Z Zas?ona et al. (2020-02-26), Caspase-11 promotes allergic airway inflammation Nat Commun, 2020-011(1):1055.
PMID: 32103022
Species: Mouse
Sample Types: Cell Culture Lysates
Applications: Western Blot

K Das Gupta et al. (2020-02-25), Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2 Cell Rep, 2020-030(8):2712-2728.e8.
PMID: 32101747
Species: Mouse
Sample Types: Tissue Lysates
Applications: Western Blot

B Liu et al. (2020-02-13), Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice Nutrients, 2020-012(2).
PMID: 32069862
Species: Mouse
Sample Types: Whole Tissue,Cell Lysates
Applications: IHC,Western Blot

Y Wooff et al. (2020-02-10), Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration Sci Rep, 2020-010(1):2263.
PMID: 32041990
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

D Fox et al. (2020-02-06), Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome Nat Commun, 2020-011(1):760.
PMID: 32029733
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

J Kim et al. (2020-01-07), I&kappaB? controls NLRP3 inflammasome activation via upregulation of the Nlrp3 gene Cytokine, 2020-0127(0):154983.
PMID: 31918161
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

A Bhatta et al. (2019-12-13), A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome J. Immunol., 2019-10(0).
PMID: 31836654
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

M Speir et al. (2019-12-09), Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation Nat. Immunol., 2019-121(1):54-64.
PMID: 31819256
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

J Wang et al. (2019-12-09), Identification of hub genes and key pathways of dietary advanced glycation end products?induced non?alcoholic fatty liver disease by bioinformatics analysis and animal experiments Mol Med Rep, 2019-121(2):685-694.
PMID: 31974594
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

M Di Gioia et al. (2019-11-25), Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation Nat. Immunol., 2019-10(0).
PMID: 31768073
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

T Yoshizaki et al. (2019-11-19), IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice Sci Rep, 2019-19(1):17067.
PMID: 31745167
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Y Chen et al. (2019-10-09), Gasdermin D Drives the Nonexosomal Secretion of Galectin-3, an Insulin Signal Antagonist J. Immunol., 2019-10(0).
PMID: 31597705
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

MM Hughes et al. (2019-10-01), Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation Cell Rep, 2019-129(1):151-161.e5.
PMID: 31577945
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

P Wang et al. (2019-09-26), CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells Aging (Albany NY), 2019-011(18):7402-7415.
PMID: 31557129
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

P Samir et al. (2019-09-11), DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome Nature, 2019-00(0).
PMID: 31511697
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

MK Akula et al. (2019-09-04), Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions Nat Commun, 2019-010(1):3975.
PMID: 31484924
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Mian Wu et al. (2019-06-28), Chaetocin attenuates gout in mice through inhibiting HIF-1? and NLRP3 inflammasome-dependent IL-1? secretion in macrophages Arch. Biochem. Biophys., 2019-00(0).
PMID: 31255694
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Q Lin et al. (2019-06-11), PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation Redox Biol, 2019-026(0):101254.
PMID: 31229841
Species: Mouse
Sample Types: Tissue Lysates
Applications: Western Blot

MR Spalinger et al. (2019-05-20), Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner J. Clin. Invest., 2019-0130(0):2527-2541.
PMID: 31107248
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

LS da Costa et al. (2019-04-25), RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux Cell Death Dis, 2019-010(5):346.
PMID: 31024004
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

DM Ojcius et al. (2019-04-23), Dicer regulates activation of the NLRP3 inflammasome PLoS ONE, 2019-014(4):e0215689.
PMID: 31013297
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

R Meng et al. (2019-04-18), High mobility group box 1 enables bacterial lipids to trigger receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis and apoptosis in mice J. Biol. Chem., 2019-00(0).
PMID: 31000631
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

VS Tapia et al. (2019-04-02), The three cytokines IL-1?, IL-18, and IL-1? share related but distinct secretory routes J. Biol. Chem., 2019-0294(21):8325-8335.
PMID: 30940725
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

P Zhang et al. (2019-04-02), The lncRNA Neat1 promotes activation of inflammasomes in macrophages Nat Commun, 2019-010(1):1495.
PMID: 30940803
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

H Cui et al. (2019-02-21), Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury JCI Insight, 2019-00(0).
PMID: 30676324
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr

S Morita-Tak et al. (2019-02-14), Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance J Neuroinflammation, 2019-016(1):39.
PMID: 30764851
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Z Erlich et al. (2019-02-11), Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model Nat. Immunol., 2019-00(0).
PMID: 30742078
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

WL Hwang et al. (2019-01-25), Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer J Hematol Oncol, 2019-012(1):10.
PMID: 30683126
Species: Mouse
Sample Types: Aqueous Humor
Applications: Western Blot

J Lee et al. (2019-01-20), Injury induces endothelial to mesenchymal transition in the mouse corneal endothelium in vivo via FGF2 Mol. Vis., 2019-025(0):22-34.
PMID: 30804659
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P

RT Gunaratna et al. (2019-01-16), Dynamic role of the codon 72 p53 single-nucleotide polymorphism in mammary tumorigenesis in a humanized mouse model Oncogene, 2019-00(0).
PMID: 30651598
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

D Kurundkar et al. (2019-01-10), SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury JCI Insight, 2019-04(1).
PMID: 30626741
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

C Widmann et al. (2018-12-24), The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia Sci Rep, 2018-18(1):18062.
PMID: 30584250
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

A Mathur et al. (2018-12-10), A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome Nat Microbiol, 2018-10(0).
PMID: 30531979
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

JE Vince et al. (2018-11-27), The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1? Activation Cell Rep, 2018-125(9):2339-2353.e4.
PMID: 30485804
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

B Koch et al. (2018-11-20), A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling Cell Rep, 2018-125(8):2244-2258.e7.
PMID: 30463019
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

D Sharma et al. (2018-11-19), TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy J. Clin. Invest., 2018-10(0).
PMID: 30457980
L Kasper et al. (2018-10-15), The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes Nat Commun, 2018-19(1):4260.
PMID: 30323213
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

S Wang et al. (2018-10-12), REV-ERB? integrates colon clock with experimental colitis through regulation of NF-?B/NLRP3 axis Nat Commun, 2018-19(1):4246.
PMID: 30315268
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

JT Benjamin et al. (2018-10-10), Cutting Edge: IL-1? and Not IL-1? Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality J. Immunol., 2018-10(0).
PMID: 30305325
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P

Z Zhang et al. (2018-09-24), Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury Cell Death Dis, 2018-09(10):983.
PMID: 30250284
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

M Monteleone et al. (2018-08-07), Interleukin-1? Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion Cell Rep, 2018-024(6):1425-1433.
PMID: 30089254
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

C Marchetti et al. (2018-08-03), NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis Arthritis Res. Ther., 2018-020(1):169.
PMID: 30075804
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Y Chen et al. (2018-07-22), NLRP3 Inflammasome Formation and Activation in Nonalcoholic Steatohepatitis: Therapeutic Target for Antimetabolic Syndrome Remedy FTZ Oxid Med Cell Longev, 2018-02018(0):2901871.
PMID: 30140364
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

M Shahid et al. (2018-07-18), Menthol, a unique urinary volatile compound, is associated with chronic inflammation in interstitial cystitis Sci Rep, 2018-08(1):10859.
PMID: 30022124
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

H He et al. (2018-06-29), Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity Nat Commun, 2018-09(1):2550.
PMID: 29959312
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

E Lee et al. (2018-05-21), MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration Cell Death Differ., 2018-00(0).
PMID: 29786072
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

H Ahn et al. (2018-04-04), Nonsaponin fraction of Korean Red Ginseng attenuates cytokine production via inhibition of TLR4 expression J Ginseng Res, 2018-043(2):291-299.
PMID: 30976167
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Y Huang et al. (2018-04-01), Tranilast directly targets NLRP3 to treat inflammasome-driven diseases EMBO Mol Med, 2018-00(0).
PMID: 29531021
Species: Mouse
Sample Types: Protein
Applications: Western Blot

LG Coleman et al. (2018-03-30), HMGB1/IL-1? complexes in plasma microvesicles modulate immune responses to burn injury PLoS ONE, 2018-013(3):e0195335.
PMID: 29601597
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

C Cochain et al. (2018-03-15), Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis Circ. Res., 2018-00(0).
PMID: 29545365
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

LH Chu et al. (2018-03-08), The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages Nat Commun, 2018-09(1):996.
PMID: 29520027
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

W Zhuang et al. (2018-03-06), MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss Int. J. Mol. Med., 2018-00(0).
PMID: 29512778
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

SB Kwak et al. (2018-03-04), Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation Mediators Inflamm., 2018-02018(0):6054069.
PMID: 29686531
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

RG Carroll et al. (2018-02-20), An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation J. Biol. Chem., 2018-0293(15):5509-5521.
PMID: 29463677
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

JC Santos et al. (2018-02-19), LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation EMBO J., 2018-00(0).
PMID: 29459437
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

D Boucher et al. (2018-02-06), Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity J. Exp. Med., 2018-00(0).
PMID: 29432122
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

YK Kim et al. (2018-01-18), Inhibitory Effect and Mechanism ofArctium lappaExtracton NLRP3Inflammasome Activation Evid Based Complement Alternat Med, 2018-02018(0):6346734.
PMID: 29576797
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

JL Ross et al. (2018-01-03), Sex differences in primary muscle afferent sensitization following ischemia and reperfusion injury Biol Sex Differ, 2018-09(1):2.
PMID: 29298725
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

K Zenke et al. (2017-12-11), AKT1 distinctively suppresses MyD88-depenedent and TRIF-dependent Toll-like receptor signaling in a kinase activity-independent manner Cell. Signal., 2017-143(0):32-39.
PMID: 29242168
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Ghosh et al. (2017-09-20), The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression J. Immunol., 2017-00(0).
PMID: 28931603
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

JC Rivera et al. (2017-09-06), Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina J Neuroinflammation, 2017-014(1):181.
PMID: 28874201
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

EM McDonough et al. (2017-08-17), MTG16 is a tumor suppressor in colitis-associated carcinoma JCI Insight, 2017-02(16).
PMID: 28814670
Species: Mouse
Sample Types: Whole Tissue,Tissue Homogenates
Applications: Western Blot,IHC

F Albalawi et al. (2017-08-08), The P2X7 Receptor Primes IL-1? and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain Front Cell Neurosci, 2017-011(0):227.
PMID: 28848393
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

B Brawek et al. (2017-07-20), A new approach for ratiometric in vivo calcium imaging of microglia Sci Rep, 2017-07(1):6030.
PMID: 28729628
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

S Yoon et al. (2017-06-27), MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation Immunity, 2017-00(0).
PMID: 28666573
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

T Wu et al. (2017-06-23), Nucleoside reverse transcriptase inhibitors (NRTIs) induce proinflammatory cytokines in the CNS via Wnt5a signaling Sci Rep, 2017-07(1):4117.
PMID: 28646196
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

R Domingo-Fe et al. (2017-06-02), The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1? transcription and activate the NLRP3 inflammasome J. Biol. Chem., 2017-00(0).
PMID: 28576828
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

V Neudecker et al. (2017-05-09), Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome J. Exp. Med., 2017-00(0).
PMID: 28487310
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Q Zhu et al. (2017-05-03), Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1? J. Immunol., 2017-00(0).
PMID: 28468974
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

H Ahn et al. (2017-05-02), Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production Sci Rep, 2017-07(1):1314.
PMID: 28465544
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Y Kanamori et al. (2017-04-24), IL-1? transcriptionally activates hepcidin by inducing C/EBP? expression in hepatocytes J. Biol. Chem., 2017-00(0).
PMID: 28438835
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

L Freeman et al. (2017-04-12), NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes J. Exp. Med., 2017-00(0).
PMID: 28404595
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Z Zhong et al. (2017-04-11), Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc(Min/+) mice Nat Commun, 2017-08(0):15004.
PMID: 28397782
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

MK Choo et al. (2017-04-11), TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects J. Exp. Med., 2017-0214(5):1297-1311.
PMID: 28400473
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

K Moriwaki et al. (2017-03-07), Distinct Kinase-Independent Role of RIPK3 in CD11c(+) Mononuclear Phagocytes in Cytokine-Induced Tissue Repair Cell Rep, 2017-018(10):2441-2451.
PMID: 28273458
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

H Youssef et al. (2017-03-01), Interleukin-1 and estrogen protect against disseminating dentoalveolar infections Int J Oral Sci, 2017-09(1):16-23.
PMID: 28358036
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

TP Domiciano et al. (2017-02-02), Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis Sci Rep, 2017-07(0):41539.
PMID: 28148962
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

M Tsugita et al. (2017-01-31), SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation Cell Rep, 2017-018(5):1298-1311.
PMID: 28147282
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

O Tufanli et al. (2017-01-30), Targeting IRE1 with small molecules counteracts progression of atherosclerosis Proc. Natl. Acad. Sci. U.S.A, 2017-00(0).
PMID: 28137856
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

HJ Koh et al. (2017-01-26), Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCï¿½ PLoS Pathog, 2017-013(1):e1006126.
PMID: 28125719
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

(2016-12-20), Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis Sci Rep, 2016-16(0):39257.
PMID: 27995963
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

(2016-12-07), Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation PLoS Pathog, 2016-112(12):e1006052.
PMID: 27926929
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

(2016-11-28), TNF?-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury Proc. Natl. Acad. Sci. U.S.A., 2016-1113(50):E8151-E8158.
PMID: 27911817
Species: Mouse
Sample Types: Tissue Homogenates,Whole Tissue
Applications: IHC,Western Blot

Jeremy S Duffield (2016-11-21), Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury J. Clin. Invest., 2016-10(0).
PMID: 27869651
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

(2016-09-27), CARD9 negatively regulates NLRP3-induced IL-1? production on Salmonella infection of macrophages Nat Commun, 2016-07(0):12874.
PMID: 27670879
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Gang Hu (2016-09-21), Fluoxetine Inhibits NLRP3 Inflammasome Activation: Implication in Depression Int. J. Neuropsychopharmacol., 2016-019(9).
PMID: 27207922
Species: Human
Sample Types: Tissue Homogenates
Applications: Western Blot

(2016-08-15), Lymphatic vessels regulate immune microenvironments in human and murine melanoma J Clin Invest, 2016-00(0).
PMID: 27525437
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

(2016-08-11), CD8+ T cells produce a dialyzable antigen-specific activator of dendritic cells J Leukoc Biol, 2016-00(0).
PMID: 27515950
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

(2016-08-01), C13orf31 (FAMIN) is a central regulator of immunometabolic function Nat Immunol, 2016-00(0).
PMID: 27478939
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

(2016-07-18), HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis J Immunol, 2016-00(0).
PMID: 27430718
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Bead-based Immunoassay

(2016-07-08), Enzymatically inactive procaspase-1 stabilizes the ASC-pyroptosome and supports pyroptosome spreading during cell division J Biol Chem, 2016-00(0).
PMID: 27402835
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P,IHC

(2016-06-28), Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J. infection Oncotarget, 2016-07(26):39316-39331.
PMID: 27322427
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Yong Hwan Park (2016-06-06), Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS Nat Immunol, 2016-00(0).
PMID: 27270401
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

X Wang et al. (2016-05-24), The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation Infect Immun, 2016-00(0).
PMID: 27045038
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Marty-Roix R et al. (2015-11-10), Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants. J Biol Chem, 2015-1291(3):1123-36.
PMID: 26555265
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Sester D et al. (2015-06-26), Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice. J Immunol, 2015-0195(3):1233-41.
PMID: 26116505
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Sadeghi H et al. (2015-03-20), Caspase-1-independent IL-1 release mediates blister formation in autoantibody-induced tissue injury through modulation of endothelial adhesion molecules. J Immunol, 2015-0194(8):3656-63.
PMID: 25795756
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr

Denes A et al. (2015-03-16), AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3. Proc Natl Acad Sci U S A, 2015-0112(13):4050-5.
PMID: 25775556
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Meunier E et al. (2015-03-16), Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida. 2015-00(0).
PMID: 25774716
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Chien C et al. (2015-02-23), Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice. PLoS ONE, 2015-010(2):e0115827.
PMID: 25706411
Species: Mouse
Sample Types: Cell Lysates,In Vivo
Applications: Neutralization,Western Blot

Lawlor K et al. (2015-02-18), RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat Commun, 2015-06(0):6282.
PMID: 25693118
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Maier N et al. (2015-02-13), The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. J Immunol, 2015-0194(6):2776-85.
PMID: 25681332
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Yang C et al. (2015-02-06), Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome. Nat Commun, 2015-06(0):6115.
PMID: 25655831
Species: Mouse
Sample Types: Tissue Homogenates,Whole Tissue
Applications: IHC,Western Blot

Li B et al. (2015-01-21), IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis. Nat Commun, 2015-06(0):6131.
PMID: 25607885
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Moriwaki K et al. (2015-01-07), A RIPK3-caspase 8 complex mediates atypical pro-IL-1beta processing. J Immunol, 2015-0194(4):1938-44.
PMID: 25567679
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Sitaras N et al. (2014-12-03), Retinal neurons curb inflammation and enhance revascularization in ischemic retinopathies via proteinase-activated receptor-2. Am J Pathol, 2014-1185(2):581-95.
PMID: 25478809
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Hari A et al. (2014-12-02), Activation of NLRP3 inflammasome by crystalline structures via cell surface contact. Sci Rep, 2014-14(0):7281.
PMID: 25445147
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Ahn H et al. (2014-11-21), Methylsulfonylmethane inhibits NLRP3 inflammasome activation. Cytokine, 2014-171(2):223-31.
PMID: 25461402
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Lim et al. (2014-09-26), Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes. Nat Commun, 2014-05(0):4934.
PMID: 25255859
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Ganesan S et al. (2014-07-25), Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1beta production in response to beta-glucans and the fungal pathogen, Candida albicans. J Immunol, 2014-0193(5):2519-30.
PMID: 25063877
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Asrat S et al. (2014-07-24), The frustrated host response to Legionella pneumophila is bypassed by MyD88-dependent translation of pro-inflammatory cytokines. PLoS Pathog, 2014-010(7):e1004229.
PMID: 25058342
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Kajiwara Y et al. (2014-05-30), A critical role for human caspase-4 in endotoxin sensitivity. J Immunol, 2014-0193(1):335-43.
PMID: 24879791
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Zhao C et al. (2014-05-05), Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J Biol Chem, 2014-0289(24):17020-9.
PMID: 24798340
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Nieto-Torres J et al. (2014-05-01), Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis. PLoS Pathog, 2014-010(5):e1004077.
PMID: 24788150
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Meunier E et al. (2014-04-16), Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature, 2014-0509(7500):366-70.
PMID: 24739961
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Rabolli V et al. (2014-04-03), Critical role of aquaporins in interleukin 1beta (IL-1beta)-induced inflammation. J Biol Chem, 2014-0289(20):13937-47.
PMID: 24700466
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Gupta R et al. (2014-04-01), RNA and beta-hemolysin of group B Streptococcus induce interleukin-1beta (IL-1beta) by activating NLRP3 inflammasomes in mouse macrophages. J Biol Chem, 2014-0289(20):13701-5.
PMID: 24692555
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Xia M et al. (2014-03-13), Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am J Pathol, 2014-0184(5):1617-28.
PMID: 24631027
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Kanarek N et al. (2014-01-27), Critical role for IL-1beta in DNA damage-induced mucositis. Proc Natl Acad Sci U S A, 2014-0111(6):E702-11.
PMID: 24469832
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Maier N et al. (2013-12-13), Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes. J Immunol, 2013-1192(2):763-70.
PMID: 24337744
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr

Tanaka S et al. (2013-12-01), Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice. J Neuroinflammation, 2013-110(0):143.
PMID: 24289537
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

He Y et al. (2013-11-21), 3,4-methylenedioxy-beta-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. J Biol Chem, 2013-1289(2):1142-50.
PMID: 24265316
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Smedberg J et al. (2013-11-06), Signaling pathways in murine dendritic cells that regulate the response to vesicular stomatitis virus vectors that express flagellin. J Virol, 2013-188(2):777-85.
PMID: 24198430
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Li B et al. (2013-03-28), Wingless-type mammary tumor virus integration site family, member 5A (Wnt5a) regulates human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein 120 (gp120)-induced expression of pro-inflammatory cytokines via the Ca2+/calmodulin-dependent protein kinase II (CaMKII) and c-Jun N-terminal kinase (JNK) signaling pathways. J Biol Chem, 2013-0288(19):13610-9.
PMID: 23539626
Species: Mouse
Sample Types: Peritoneal Fluid
Applications: Western Blot

Misawa T et al. (2013-03-17), Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. Nat Immunol, 2013-014(5):454-60.
PMID: 23502856
Species: Mouse
Sample Types: Matrigel Plug,In Vivo
Applications: IHC-Fr,IHC-P,Neutralization

Carmi Y et al. (2013-03-08), The role of IL-1beta in the early tumor cell-induced angiogenic response. J Immunol, 2013-0190(7):3500-9.
PMID: 23475218
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

El-Zaatari M et al. (2013-03-08), Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE, 2013-08(3):e58935.
PMID: 23520544
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Lee G et al. (2012-11-11), The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature, 2012-1492(7427):123-7.
PMID: 23143333
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Broz P et al. (2012-08-15), Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature, 2012-0490(7419):288-91.
PMID: 22895188
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Gessner MA et al. (2011-10-28), Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus. Infect. Immun., 2011-180(1):410-7.
PMID: 22038916
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Kim D et al. (2011-09-28), Toll-like receptor 2 contributes to chemokine gene expression and macrophage infiltration in the dorsal root ganglia after peripheral nerve injury. Mol Pain, 2011-07(0):74.
PMID: 21951975
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Fisher DT et al. (2011-09-19), IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. J. Clin. Invest., 2011-0121(10):3846-59.
PMID: 21926464
Species: Mouse
Sample Types: Whole Tissue,Whole Cells,In Vivo
Applications: IHC-Fr,ICC,Neutralization

Rider P et al. (2011-09-19), IL-1alpha and IL-1beta recruit different myeloid cells and promote different stages of sterile inflammation. J. Immunol., 2011-0187(9):4835-43.
PMID: 21930960
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot

Bergsbaken T et al. (2011-07-29), Coordinated Host Responses during Pyroptosis: Caspase-1-Dependent Lysosome Exocytosis and Inflammatory Cytokine Maturation. J. Immunol., 2011-0187(5):2748-54.
PMID: 21804020
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Carmi Y et al. (2011-02-07), Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis. J. Immunol., 2011-0186(6):3462-71.
PMID: 21300825
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Yoshida H et al. (2010-10-22), Interleukin-1beta mediates the extra-intestinal thrombosis associated with experimental colitis. Am. J. Pathol., 2010-1177(6):2774-81.
PMID: 20971730
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

McCoy AJ et al. (2010-10-01), Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages. Eur. J. Immunol., 2010-140(10):2797-803.
PMID: 20722078
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Masters SL et al. (2010-09-12), Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat. Immunol., 2010-011(10):897-904.
PMID: 20835230
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Radwan M et al. (2010-08-16), Tyrosine kinase 2 controls IL-1beta production at the translational level. J. Immunol., 2010-0185(6):3544-53.
PMID: 20713887
Species: Mouse
Sample Types: DNA
Applications: MUSTag PCR Assay

Ohno T et al. (2009-12-15), Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J. Immunol., 2009-1183(12):7890-7.
PMID: 19933859
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Ghiringhelli F et al. (2009-09-20), Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med., 2009-015(10):1170-8.
PMID: 19767732
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Martin U et al. (2009-08-28), Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages. J. Immunol., 2009-0183(6):4021-30.
PMID: 19717513
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P

Babelova A et al. (2009-07-15), Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem, 2009-0284(36):24035-48.
PMID: 19605353
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P

Hyvarinen K et al. (2009-05-18), Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice. Infect. Immun., 2009-077(8):3442-9.
PMID: 19451238
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Maelfait J et al. (2008-08-25), Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J. Exp. Med., 2008-0205(9):1967-73.
PMID: 18725521
Species: Mouse
Sample Types: Tissue Homogenates,Whole Tissue
Applications: Western Blot,IHC-Fr

Das S et al. (2008-03-28), Japanese Encephalitis Virus infection induces IL-18 and IL-1beta in microglia and astrocytes: correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death. J. Neuroimmunol., 2008-0195(1):60-72.
PMID: 18374991
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Miller LS et al. (2007-11-15), Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. J. Immunol., 2007-1179(10):6933-42.
PMID: 17982084
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Pozsgai G et al. (2007-11-01), Topical acetone treatment induces neurogenic oedema on the sensitized mouse ear: an in vivo study using transient receptor potential vanilloid 1 (TRPV1) receptor knockout mice. Inflamm. Res., 2007-156(11):459-67.
PMID: 18224287
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Ogiso T et al. (2007-08-10), Granulocyte colony-stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-1beta. J. Hepatol., 2007-047(6):816-25.
PMID: 17869372
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Medeiros MM et al. (2007-05-31), Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi. J. Leukoc. Biol., 2007-082(3):488-96.
PMID: 17540734
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Shchors K et al. (2006-09-15), The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta. Genes Dev., 2006-020(18):2527-38.
PMID: 16980582
Species: Mouse
Applications: Neutralization

Perrin FE et al. (2005-02-02), Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration. Brain, 2005-0128(0):854-66.
PMID: 15689362
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Banks WA et al. (2001-11-01), Intravenous human interleukin-1alpha impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum. J. Pharmacol. Exp. Ther., 2001-1299(2):536-41.
PMID: 11602664

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Customer Reviews for Mouse IL‑1 beta/IL‑1F2 Antibody (24)

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Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: Aorta tissue

Species: Mouse

Verified Customer | Posted 07/25/2023
Mouse IL-1 beta /IL-1F2 Antibody

Name: Katie Myers

Application: ELISA

Sample Tested: Serum

Species: Mouse

Verified Customer | Posted 11/29/2022

Used as ELISA detection
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Western Blot

Sample Tested: Lysates of primary bone marrow derived macrophage

Species: Mouse

Verified Customer | Posted 11/08/2022

IL-1beta band comes at 32 KDa for the pro-IL-1b.
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Flow Cytometry

Sample Tested: Leukocyte

Species: Mouse

Verified Customer | Posted 08/28/2022

Works well with flow cytometry!
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Flow Cytometry

Sample Tested: Peripheral blood mononuclear cells (PBMCs)

Species: Human

Verified Customer | Posted 12/14/2021

PBMCs either left resting or stimulated with LPS (1ug, 3h). Addition of GolgiPlug to detect intracellular IL1B production. Use of a secondary anti-goat antibody, conjugated to AF488.
Mouse IL-1 beta /IL-1F2 Antibody

Name: Tina Yuan

Application: Immunohistochemistry

Sample Tested: mouse oral tissue

Species: Mouse

Verified Customer | Posted 11/23/2020
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Western Blot

Sample Tested: THP-1 human acute monocytic leukemia cell line

Species: Human

Verified Customer | Posted 11/19/2020

Human-derived THP-1 cells either left unstimulated or treated with LPS+ATP for 3 hours. Intracellular detection.
Mouse IL-1 beta /IL-1F2 Antibody

Name: Miguel Lopez Cuina

Application: Western Blot

Sample Tested: Brain (caudate putamen)

Species: Mouse

Verified Customer | Posted 05/23/2019

I am somewhat disappointed. My lab published 4 years ago an article using this Ab. I boight it last september. There is no way I can get the bands ourselves and other authors have published: the proIL1-beta and the mature form, at around 35 and 17kDa. Attached is a representative blot of the many I have run. I have tried homemade 12% gels, BioRad 12 and 4-20% precast gels. I have tried both types of membranes (PVDF and Nitro 0.2), blocking with milk and BSA, different transfer times (35min 120V, 45min 100V, 1h 100V, 1.5h 100V), different Ab dilutions. And I still get nothing that comes to close to the pro-IL-1beta, and of course, the mature form is nowhere to be found. I do not wish to buy another brand, I believe this to be a good Ab, but since it is polyclonal, it might give different results depending on the lot. ***Bio-Techne Response: Thank you for reviewing our product. We are sorry to hear that this antibody did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction.***
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Western Blot

Sample Tested: IC-21 mouse macrophage cell line

Species: Mouse

Verified Customer | Posted 01/28/2019
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anthony Morales

Application: Western Blot

Sample Tested: IC-21 mouse macrophage cell line

Species: Mouse

Verified Customer | Posted 01/28/2019
Mouse IL-1 beta /IL-1F2 Antibody

Name: CARLA RAMON

Application: Immunohistochemistry

Sample Tested: Brain tissue

Species: Mouse

Verified Customer | Posted 08/08/2018

10.1093/cercor/bhy164
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Simple Western

Sample Tested: J774A.1 mouse reticulum cell sarcoma macrophage cell line

Species: Mouse

Verified Customer | Posted 07/17/2018
Mouse IL-1 beta /IL-1F2 Antibody

Name: Paloma Narros

Application: Western Blot

Sample Tested: Cell Lysates and Macrophages Cell Supernatant

Species: Mouse and Mouse macrophages

Verified Customer | Posted 07/17/2018
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Western Blot

Sample Tested: Cell Lysates

Species: Mouse

Verified Customer | Posted 07/17/2018
Mouse IL-1 beta /IL-1F2 Antibody

Name: Alisha Freeman

Application: ELISA

Sample Tested: A549 human lung carcinoma cell line

Species: Human

Verified Customer | Posted 05/17/2018
Mouse IL-1 beta /IL-1F2 Antibody

Name: Rupal Soder

Application: Western Blot

Sample Tested: IC-21 mouse macrophage cell line

Species: Mouse

Verified Customer | Posted 03/22/2018
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Western Blot

Sample Tested: bone marrow derived macrophage

Species: Mouse

Verified Customer | Posted 10/31/2017
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Flow Cytometry

Sample Tested: L-929 mouse fibroblast cell line

Species: Mouse

Verified Customer | Posted 09/08/2017
Mouse IL-1 beta /IL-1F2 Antibody

Name: Michelle Chen

Application: Block/Neutralize

Sample Tested: Adult splenocytes

Species: Mouse

Verified Customer | Posted 04/26/2017
Mouse IL-1 beta /IL-1F2 Antibody

Name: Goutham Pattabiraman

Application: Western Blot

Sample Tested: Bone marrow cells, Serum-free Cell Culture Supernates and Cell culture supernatant

Species: Mouse

Verified Customer | Posted 04/25/2017
Mouse IL-1 beta /IL-1F2 Antibody

Name: Anonymous

Application: Western Blot

Sample Tested: bone marrow derived macrophages

Species: Mouse

Verified Customer | Posted 02/14/2017
Name: Anonymous -

Application: Western Blot

Sample Tested: See PMID 23160153

Species: Mouse

Verified Customer | Posted 01/08/2015
Name: Anonymous -

Application: Immunocytochemistry

Sample Tested: See PMID 23920123

Species: Mouse

Verified Customer | Posted 01/08/2015
Name: Anonymous -

Application: ELISA

Sample Tested: See PMID 21709053

Species: Mouse

Verified Customer | Posted 01/08/2015

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FAQs for Mouse IL‑1 beta/IL‑1F2 Antibody

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Q: Does catalog # AF-401-NA detect the pro or mature form of IL-1 beta in western blot?

A: This would depend on the sample being used. The pro-form of the protein also contains the sequence for the mature form. When cell lysates are used as the sample, the pro-form is mainly detected. When cell culture supernatants containing mainly the mature form of the protein is used, only the mature form is detected. This is exemplified in the following paper: J Immunol.(2015) 195, 1233. http://www.jimmunol.org/content/195/3/1233/tab-figures-data
Q: Does Mouse IL-1 beta /IL-1F2 Antibody, Catalog # AF-401-NA, detect cleaved IL-1beta (17kDa)?

A: The immunogen that was used to produce Catalog # AF-401-NA consists of the mature form of IL-1beta, amino acids Val118-Ser269. Since the pro-form also includes this sequence, we expect this antibody to detect the pro-form and cleaved IL-1beta.

Showing 1 - 2 of 2 FAQs Showing All

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Mouse IL‑1 beta/IL‑1F2 Antibody Best Seller

Catalog # AF-401-NA | R&D Systems, Inc. a Bio-Techne Brand

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Detection of Human and Mouse IL‑1 beta/IL‑1F2 by Western Blot.

IL‑1 beta/IL‑1F2 in MCF‑7 Human Cell Line.

IL‑1 beta/IL‑1F2 in Mouse Thymus.

Detection of Mouse IL‑1 beta/IL‑1F2 by Simple WesternTM.

Cell Proliferation Induced by IL‑1 beta/IL‑1F2 and Neutralization by Mouse IL-1 beta/IL-1F2 Antibody.

Detection of IL‑1 beta/IL‑1F2 in Mouse Intestine.

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Citations for Mouse IL‑1 beta/IL‑1F2 Antibody (269)

Customer Reviews for Mouse IL‑1 beta/IL‑1F2 Antibody (24)

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Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

Mouse IL-1 beta /IL-1F2 Antibody

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Detection of Mouse IL‑1 beta/IL‑1F2 by Simple Western^TM.