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IL-1 beta/IL-1F2: Proteins and Enzymes
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
14 results for "IL-1 beta/IL-1F2 Proteins and Enzymes" in Products
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IL-1 beta/IL-1F2: Proteins and Enzymes
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
14 results for "IL-1 beta/IL-1F2 Proteins and Enzymes" in Products
BA
| Source : | E. coli |
| Accession # : | NP_000567 |
| Applications : | Bioactivity |
BA
| Source : | E. coli |
| Accession # : | NP_032387 |
| Applications : | Bioactivity |
Catalog #:
201-GMP
BA
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| Source : | E. coli |
| Accession # : | NP_000567.1 |
| Applications : | Bioactivity |
BA
| Source : | E. coli |
| Accession # : | Q63264 |
| Applications : | Bioactivity |
Catalog #:
AFL201
BA
Also available, GMP IL-1beta Protein, Catalog # 201-GMP! Animal-free and manufactured under GMP guidelines for therapeutic manufacturing applications.
| Source : | E. coli |
| Accession # : | NP_000567 |
| Applications : | Bioactivity |
Catalog #:
3747-CL
BA
| Source : | E. coli |
| Accession # : | NP_001033060 |
| Applications : | Bioactivity |
Catalog #:
1796-FL
BA
| Source : | E. coli |
| Accession # : | P41687.1 |
| Applications : | Bioactivity |
Catalog #:
AFL401
BA
| Source : | E. coli |
| Accession # : | NP_032387 |
| Applications : | Bioactivity |
Catalog #:
6226-GL
BA
| Source : | E. coli |
| Accession # : | Q9WVG1.1 |
| Applications : | Bioactivity |
Catalog #:
1009-CL
BA
| Source : | E. coli |
| Accession # : | AAL18817 |
| Applications : | Bioactivity |
Catalog #:
7464-RB
BA
| Source : | E. coli |
| Accession # : | NP_001075670 |
| Applications : | Bioactivity |
BA
| Source : | E. coli |
| Accession # : | P26889.1 |
| Applications : | Bioactivity |
Catalog #:
1318-RL
BA
| Source : | E. coli |
| Accession # : | P48090 |
| Applications : | Bioactivity |
BA
| Source : | E. coli |
| Accession # : | Q28386 |
| Applications : | Bioactivity |
