Recombinant Mouse IL-1 beta/IL-1F2 Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | E. coli |
Accession #: | NP_032387 |
Applications: | Bioactivity |
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Citations for Recombinant Mouse IL-1 beta/IL-1F2 Protein (247)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse IL-1 beta/IL-1F2 Protein include:
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Species: Mouse
Sample Types: Whole Tissue
Applications: Organ CultureCK Cheng et al. (2023), SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis Journal of advanced research, 43(0):187-203.
PMID: 36585108 -
Species: Rat
Sample Types: Whole Cells
Applications: Cell CultureA Stancic et al. (2022), Ferroptosis as a Novel Determinant of beta-Cell Death in Diabetic Conditions Oxidative Medicine and Cellular Longevity, 2022(0):3873420.
PMID: 35320979 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Ma et al. (2022), RORgammat phosphorylation protects against T�cell-mediated inflammation Cell Reports, 38(11):110520.
PMID: 35294872 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Jiang et al. (2022), Friedelin Alleviates the Pathogenesis of Collagenase-Induced Tendinopathy in Mice by Promoting the Selective Autophagic Degradation of p65 Nutrients, 14(8).
PMID: 35458235 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Guo et al. (2022), Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway Frontiers in Pharmacology, 13(0):791376.
PMID: 35359876 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Yogev et al. (2022), CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T�cell survival Cell Reports, 38(13):110565.
PMID: 35354043 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAS Wilson et al. (2022), Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2 Nature Communications, 13(1):528.
PMID: 35082281 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHW Cheng et al. (2022), Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function Nature Communications, 13(1):2027.
PMID: 35440118 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Yin et al. (2022), Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32 Cell Death Disease, 2022;13(6):567.
PMID: 35739102 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLEA Damasceno et al. (2022), STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program Cell Reports, 39(8):110838.
PMID: 35613599 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMM Tsai et al. (2022), Brain Protective Effect of Resveratrol via Ameliorating Interleukin-1beta-Induced MMP-9-Mediated Disruption of ZO-1 Arranged Integrity Biomedicines, 10(6).
PMID: 35740292 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHZ Yu et al. (2022), NR4A1 agonist cytosporone B attenuates neuroinflammation in a mouse model of multiple sclerosis Oncogene, 17(12):2765-2770.
PMID: 35662227 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Kamei et al. (2022), Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement Oncogene, 12(1):9243.
PMID: 35654941 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Navarrete et al. (2022), A cannabidiol aminoquinone derivative activates the PP2A/B55alpha/HIF pathway and shows protective effects in a murine model of traumatic brain injury Journal of Neuroinflammation, 19(1):177.
PMID: 35810304 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Filliol et al. (2022), Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis Nature, 0(0).
PMID: 36198802 -
Species: Mouse
Sample Types: Whole Cell
Applications: BioassayL Rani et al. (2022), IL-3 regulates the differentiation of pathogenic Th17 cells European Journal of Immunology, 0(0).
PMID: 36074916 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoAG Yates et al. (2022), Montelukast reduces grey matter abnormalities and functional deficits in a mouse model of inflammation-induced encephalopathy of prematurity Journal of Neuroinflammation, 19(1):265.
PMID: 36309753 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKK Myo Min et al. (2022), Desmoglein-2 is important for islet function and beta-cell survival Cell Death Disease, 2022;13(10):911.
PMID: 36309486 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureX Yao et al. (2021), Chondrocyte ferroptosis contribute to the progression of osteoarthritis Journal of Orthopaedic Translation, 27(0):33-43.
PMID: 33376672 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Lu et al. (2021), MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-&kappaB pathway Cell Death Disease, 2021;12(6):533.
PMID: 34031369 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Shi et al. (2021), N4BP1 negatively regulates NF-&kappaB by binding and inhibiting NEMO oligomerization Nature Communications, 12(1):1379.
PMID: 33654074 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHR Clark et al. (2021), Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level Nature Communications, 12(1):1836.
PMID: 33758175 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Singh et al. (2021), Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells Scientific Reports, 11(1):11498.
PMID: 34075120 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Farré-Alin et al. (2021), Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients Biomedicines, 9(6).
PMID: 34070533 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoX Han et al. (2021), Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy Redox Biology, 44(0):102010.
PMID: 34082381 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Dupraz et al. (2021), Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal &gamma&delta T�cells Cell Reports, 36(1):109332.
PMID: 34233192 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayELY Chen et al. (2021), Ontogenic timing, T�cell receptor signal strength, and Notch signaling direct &gamma&delta T�cell functional differentiation in�vivo Cell Reports, 35(10):109227.
PMID: 34107257 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDW Kwak et al. (2021), Leukotriene B4 Receptors Are Necessary for the Stimulation of NLRP3 Inflammasome and IL-1&beta Synthesis in Neutrophil-Dominant Asthmatic Airway Inflammation Biomedicines, 9(5).
PMID: 34064821 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoS Lee et al. (2021), Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes JCI Insight, 6(16).
PMID: 34423792 -
Species: Mouse
Sample Types: In Vivo
Applications: BioassayA Takahashi et al. (2021), Neuromodulatory effect of interleukin 1&beta in the dorsal raphe nucleus on individual differences in aggression Molecular Psychiatry, 0(0).
PMID: 33931727 -
Species: Mouse
Sample Types: In Vivo
Applications: BioassayR Grieshaber et al. (2021), The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments Nature Communications, 12(1):2856.
PMID: 34001893 -
Species: Mouse
Sample Types: In Vitro
Applications: BioassayL Micheli et al. (2021), Efficacy of Posidonia oceanica Extract against Inflammatory Pain: In Vivo Studies in Mice Marine Drugs, 19(2).
PMID: 33494253 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoC van de Wet et al. (2021), Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2 Redox Biology, 47(0):102160.
PMID: 34624602 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Yang et al. (2021), Novel role of circRSU1 in the progression of osteoarthritis by adjusting oxidative stress Theranostics, 11(4):1877-1900.
PMID: 33408787 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zhao et al. (2021), TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1 Cell Death and Differentiation, 0(0).
PMID: 34017102 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLM Sanmarco et al. (2021), Gut-licensed IFN&gamma+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes Nature, 0(0).
PMID: 33408417 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDK Kaushik et al. (2021), Pericytes as mediators of infiltration of macrophages in multiple sclerosis Journal of Neuroinflammation, 18(1):301.
PMID: 34952601 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Chauhan et al. (2021), Differential Cytokine-Induced Responses of Polarized Microglia Brain sciences, 11(11).
PMID: 34827481 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Duan et al. (2021), CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease Nature Communications, 12(1):7172.
PMID: 34887405 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJG Miranda et al. (2021), Dynamic changes in beta-cell [Ca2+] regulates NFAT activation, gene transcription and islet gap junction communication Oncogene, 0(0):101430.
PMID: 34979329 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayA Fu et al. (2021), Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets Cell Reports, 37(8):110037.
PMID: 34818536 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Shi et al. (2021), The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons Journal of Neuroinflammation, 18(1):261.
PMID: 34749758 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFRC Costa et al. (2021), NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes Cell Reports, 35(8):109176.
PMID: 34038731 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoM Han et al. (2021), Deficient inflammasome activation permits an exaggerated asthma phenotype in rhinovirus C-infected immature mice Mucosal Immunology, 0(0).
PMID: 34354243 -
Species: Mouse
Sample Types: Whole Cell
Applications: Cell CultureM Ichii et al. (2020), Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress Haematologica, 0(0).
PMID: 31974192 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureHG Lee et al. (2020), NFAT-Specific Inhibition by dNP2-VIVITAmeliorates Autoimmune Encephalomyelitisby Regulation of Th1 and Th17 Mol Ther Methods Clin Dev, 16(0):32-41.
PMID: 31737742 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Ma et al. (2020), MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1 Arthritis Res. Ther., 22(1):99.
PMID: 32357909 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureSY Chien et al. (2020), Noggin Inhibits IL-1&beta and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis Cells, 9(4).
PMID: 32290085 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureEM Hanschmann et al. (2020), Paracrine regulation and improvement of &beta-cell function by thioredoxin Redox Biol, 34(0):101570.
PMID: 32473461 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Hou et al. (2020), Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype Cell Death Dis, 11(5):377.
PMID: 32415059 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Huang et al. (2020), Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity Nat. Cell Biol., 0(0).
PMID: 32367047 -
Species: Mouse
Sample Types: Whole Cell
Applications: BioassayO Haidar et al. (2020), Pro-inflammatory Cytokines Drive Deregulation of Potassium Channel Expression in Primary Synovial Fibroblasts Front Physiol, 11(0):226.
PMID: 32265733 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Shimo et al. (2020), Expression and Role of IL-1&beta Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing Int J Mol Sci, 21(7).
PMID: 32235405 -
Species: Mouse
Sample Types: Cell Culture Lysates
Applications: BioassayT Osthues et al. (2020), The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain Cells, 9(7).
PMID: 32708184 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoY Dong et al. (2020), Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice J Neuroinflammation, 17(1):205.
PMID: 32635937 -
Species: Mouse
Sample Types: Cells
Applications: Cell CultureMA Wheeler et al. (2020), MAFG-driven astrocytes promote CNS inflammation Nature, 0(0).
PMID: 32051591 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureHS Son et al. (2020), Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1 &beta expression Acta Pharm Sin B, 10(3):462-474.
PMID: 32140392 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoC van de Wet et al. (2020), Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease J. Immunol., 204(4):763-774.
PMID: 31924651 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFC Simões et al. (2020), Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair Nat Commun, 11(1):600.
PMID: 32001677 -
Species: Mouse
Sample Types: Whole Cell
Applications: BioassayS Lee et al. (2020), The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response J Neuroinflammation, 17(1):299.
PMID: 33054766 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF Namai et al. (2020), Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice Exp Mol Med, 0(0).
PMID: 32989233 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureMA Maqbool et al. (2020), Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation Cell Rep, 32(7):108048.
PMID: 32814051 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Shamdani et al. (2020), Heparan sulfate functions are altered in the osteoarthritic cartilage Arthritis Research Therapy, 2020;22(1):283.
PMID: 33287871 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureE Nummenmaa et al. (2020), Transient Receptor Potential Ankyrin 1 (TRPA1) Is Involved in Upregulating Interleukin-6 Expression in Osteoarthritic Chondrocyte Models International Journal of Molecular Sciences, 22(1).
PMID: 33374841 -
Species: Mouse
Sample Types: In Vivo
Applications: BioassayJH Jang et al. (2020), Breast Cancer Cell-Derived Soluble CD44 Promotes Tumor Progression by Triggering Macrophage IL1&beta Production Cancer Res, 80(6):1342-1356.
PMID: 31969374 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Grubiši? et al. (2020), Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation Cell Rep, 32(10):108100.
PMID: 32905782 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayI Mizoguchi et al. (2020), EBV-induced gene 3 augments IL-23R&alpha protein expression through a chaperone calnexin J. Clin. Invest., 0(0).
PMID: 32809973 -
Species: Mouse
Sample Types: In Vivo
Applications: BioassayK Kwiecien et al. (2020), The methylation status of the chemerin promoter region located from -?252 to +?258�bp regulates constitutive but not acute-phase cytokine-inducible chemerin expression levels Sci Rep, 10(1):13702.
PMID: 32792625 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureH Li et al. (2020), Exploration of metformin as novel therapy for osteoarthritis: preventing cartilage degeneration and reducing pain behavior Arthritis Res. Ther., 22(1):34.
PMID: 32087740 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Liu et al. (2020), Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis Cell Rep, 32(5):107990.
PMID: 32755583 -
Species: Transgenic Mouse
Sample Types: Spheroid
Applications: BioassayAE Engler et al. (2020), Airway-Associated Macrophages in Homeostasis and Repair Cell Reports, 33(13):108553.
PMID: 33378665 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot ControlH Ito et al. (2020), NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury J. Immunol., 0(0).
PMID: 32727891 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Liu et al. (2020), Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis Cell Rep, 32(5):107990.
PMID: 32755583 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMA Maqbool et al. (2020), Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation Cell Rep, 32(7):108048.
PMID: 32814051 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoK Kwiecien et al. (2020), The methylation status of the chemerin promoter region located from -?252 to +?258�bp regulates constitutive but not acute-phase cytokine-inducible chemerin expression levels Sci Rep, 10(1):13702.
PMID: 32792625 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCJ Jhun et al. (2020), Lactobacillus sakei suppresses collagen-induced arthritis and modulates the differentiation of T helper 17 cells and regulatory B cells J Transl Med, 18(1):317.
PMID: 32799896 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoJ Kealy et al. (2020), Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium J. Neurosci., 0(0).
PMID: 32513828 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Monin et al. (2020), gammadelta T cells compose a developmentally regulated intrauterine population and protect against vaginal candidiasis Mucosal Immunol, 0(0).
PMID: 32472066 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Liu et al. (2019), NCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development EBioMedicine, 0(0).
PMID: 30827928 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJD Glenn et al. (2019), Frontline Science: Induction of experimental autoimmune encephalomyelitis mobilizes Th17-promoting myeloid derived suppressor cells to the lung J. Leukoc. Biol., 0(0).
PMID: 30762897 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Saeki et al. (2019), Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation Sci Rep, 9(1):1022.
PMID: 30705364 -
Species: Mouse
Sample Types: Protein
Applications: Specificity ControlS Morita-Tak et al. (2019), Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance J Neuroinflammation, 16(1):39.
PMID: 30764851 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Li et al. (2019), Potential Novel Prediction of TMJ-OA: MiR-140-5p Regulates Inflammation Through Smad/TGF-? Signaling Front Pharmacol, 10(0):15.
PMID: 30728776 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Yasuda et al. (2019), Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation Nat Commun, 10(1):549.
PMID: 30710091 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHG Lee et al. (2019), Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis Nat Commun, 10(1):709.
PMID: 30755603 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOM Finucane et al. (2019), The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages Sci Rep, 9(1):4034.
PMID: 30858427 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Das et al. (2019), BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis Oncogene, 0(0).
PMID: 30635655 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDH Kim et al. (2019), Estrogen receptor ? in T cells suppresses follicular helper T cell responses and prevents autoimmunity Exp. Mol. Med., 51(4):41.
PMID: 30988419 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayA Lalwani et al. (2019), ? Cell Hypoxia-Inducible Factor-1? Is Required for the Prevention of Type 1 Diabetes Cell Rep, 27(8):2370-2384.e6.
PMID: 31116982 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Darkwah et al. (2019), Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis Biomedicines, 7(3).
PMID: 31323786 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureC Lao et al. (2019), 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives as inhibitors of full-length RORγt Bioorg. Chem., 90(0):103077.
PMID: 31323598 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureTY Chan et al. (2019), Increased ILC3s associated with higher levels of IL-1? aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase Eur. J. Immunol., 0(0).
PMID: 31350760 -
Species: Rat
Sample Types: Whole Tissue
Applications: Tissue CultureG Chen et al. (2019), Interleukin-1? Promotes Schwann Cells De-Differentiation in Wallerian Degeneration via the c-JUN/AP-1 Pathway Front Cell Neurosci, 13(0):304.
PMID: 31338026 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Bensellam et al. (2019), Phlda3 regulates beta cell survival during stress Sci Rep, 9(1):12827.
PMID: 31492921 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoDT Skelly et al. (2019), Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms Mol. Psychiatry, 24(10):1533-1548.
PMID: 29875474 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA StandardJ Yu et al. (2019), Serum amyloid A-mediated inflammasome activation of microglial cells in cerebral ischemia J. Neurosci., 0(0).
PMID: 31611307 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNW Zammit et al. (2019), A20 as an immune tolerance factor can determine islet transplant outcomes JCI Insight, 4(21).
PMID: 31581152 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Pham et al. (2019), Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf Cell Rep, 29(5):1203-1220.e7.
PMID: 31665634 -
Species: Mouse
Sample Types: Tissue Homogenates
Applications: BioassayDX Ji et al. (2019), Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra Nat Microbiol, 0(0).
PMID: 31611644 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Mahmoudi et al. (2019), Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing Nature, 574(7779):553-558.
PMID: 31645721 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoP Pan et al. (2019), Dengue Virus Infection Activates Interleukin-1beta to Induce Tissue Injury and Vascular Leakage Front Microbiol, 10(0):2637.
PMID: 31824450 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureX Zhou et al. (2019), 3?-Acetyloxy-oleanolic Acid Attenuates Pristane-Induced Lupus Nephritis by Regulating Th17 Differentiation J Immunol Res, 2019(0):2431617.
PMID: 31240232 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Radulovic et al. (2019), NLRP6 Deficiency in CD4 T Cells Decreases T Cell Survival Associated with Increased Cell Death J. Immunol., 0(0).
PMID: 31152078 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoL Todd et al. (2019), Reactive microglia and IL1?/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina J Neuroinflammation, 16(1):118.
PMID: 31170999 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCC Hsieh et al. (2018), Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice Stem Cell Res Ther, 9(1):183.
PMID: 29973247 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Caughron et al. (2018), Role of IL-23 signaling in the progression of premalignant oral lesions to cancer PLoS ONE, 13(4):e0196034.
PMID: 29664967 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHV Lin et al. (2018), GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function Mol Metab, 0(0).
PMID: 29506910 -
Species: Mouse
Applications: In VivoA Song et al. (2018), Salient type 1 interleukin 1 receptor expression in peripheral non-immune cells Sci Rep, 8(1):723.
PMID: 29335509 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoCH Lee et al. (2018), C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation Elife, 7(0).
PMID: 29469805 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDB Ballak et al. (2018), Interleukin-37 Treatment of Mice with Metabolic Syndrome Improves Insulin Sensitivity and Reduces Pro-inflammatory Cytokine Production in Adipose Tissue J. Biol. Chem., 0(0).
PMID: 30006351 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJJ Seeley et al. (2018), Induction of innate immune memory via microRNA targeting of chromatin remodelling factors Nature, 559(7712):114-119.
PMID: 29950719 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCN Berger et al. (2018), The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses PLoS Pathog., 14(10):e1007406.
PMID: 30365535 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoJT Benjamin et al. (2018), Cutting Edge: IL-1? and Not IL-1? Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality J. Immunol., 0(0).
PMID: 30305325 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA (Standard)HY Nam et al. (2018), Ibrutinib suppresses LPS-induced neuroinflammatory responses in BV2 microglial cells and wild-type mice J Neuroinflammation, 15(1):271.
PMID: 30231870 -
Species: Mouse
Sample Types: Recombinant Protein
Applications: ELISA (Standard)F Dou et al. (2018), EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway Mol Brain, 11(1):75.
PMID: 30563578 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Kolb et al. (2018), Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4 Oncogene, 0(0).
PMID: 30518876 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Engelowski et al. (2018), IL-23R Signaling Plays No Role in Myocardial Infarction Sci Rep, 8(1):17078.
PMID: 30459442 -
Species: Mouse
Sample Types: Whole Cells
Applications: DifferentiationF Mathies et al. (2018), Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3+ Regulatory T Cells J. Immunol., 0(0).
PMID: 30446566 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKA de Lima et al. (2018), TGF?1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism Cell Death Dis, 9(11):1130.
PMID: 30425241 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Amir et al. (2018), REV-ERB? Regulates TH17 Cell Development and Autoimmunity Cell Rep, 25(13):3733-3749.e8.
PMID: 30590045 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHM Hsiao et al. (2018), Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1? J. Clin. Invest., 128(7):2833-2847.
PMID: 29781811 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayA Mancini et al. (2018), Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis Neurobiol. Dis., 0(0).
PMID: 29325869 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureW Klement et al. (2018), Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature Neurobiol. Dis., 0(0).
PMID: 29432809 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAJ St Leger et al. (2018), STAT-3-independent production of IL-17 by mouse innate-like ?? T cells controls ocular infection J. Exp. Med., 0(0).
PMID: 29490936 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Meyer Zu H et al. (2018), Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1 Immunity, 48(3):556-569.e7.
PMID: 29562202 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayH Kuwata et al. (2018), The group VIA calcium-independent phospholipase A2 and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts FEBS J., 0(0).
PMID: 29637744 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Di Candia et al. (2017), HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4 J. Allergy Clin. Immunol, 0(0).
PMID: 28259445 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIA Mufazalov et al. (2017), Balanced Bcl-3 expression in murine CD4(+) T cells is required for generation of encephalitogenic Th17 cells Eur. J. Immunol., 0(0).
PMID: 28598502 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayF Jiang et al. (2017), The symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis inhibits IL-1?-induced inflammation in human fetal enterocytes via toll receptors 2 and 4 PLoS ONE, 12(3):e0172738.
PMID: 28278201 -
Species: Mouse
Applications: ELISA (Standard)SY Nam et al. (2017), Anti-inflammatory effects of a traditional Korean medicine: Ojayeonjonghwan Pharm Biol, 55(1):1856-1862.
PMID: 28614972 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAM Yang et al. (2017), Intestinal fungi contribute to development of alcoholic liver disease J. Clin. Invest., 0(0).
PMID: 28530644 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQH Wang et al. (2017), Pharmacological Effect ofCaulophyllum robustumon Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-?B, and Proinflammatory Cytokines In Vivo and In Vitro Evid Based Complement Alternat Med, 2017(0):8134321.
PMID: 29456573 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Wang et al. (2017), TNF-? promotes extracellular vesicle release in mouse astrocytes through glutaminase J Neuroinflammation, 14(1):87.
PMID: 28427419 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTM Nordmann et al. (2017), The Role of Inflammation in ?-cell Dedifferentiation Sci Rep, 7(1):6285.
PMID: 28740254 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Zhao et al. (2017), Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota J. Immunol., 0(0).
PMID: 28539431 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Franchi et al. (2017), Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis J. Immunol, 0(0).
PMID: 28242647 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoMC Lee et al. (2017), G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease J. Immunol, 0(0).
PMID: 28320832 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Kamizaki et al. (2017), The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle J. Biol. Chem., 0(0).
PMID: 28790171 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCX Yi et al. (2017), TNF? drives mitochondrial stress in POMC neurons in obesity Nat Commun, 8(0):15143.
PMID: 28489068 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF Reverchon et al. (2017), IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria PLoS Pathog., 13(4):e1006322.
PMID: 28448579 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoS Choi et al. (2017), Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis J. Clin. Invest, 127(3):954-969.
PMID: 28192374 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayY Haim et al. (2017), ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype Mol Metab, 6(7):725-736.
PMID: 28702328 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoMG Ledesma-Co et al. (2017), Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis Arthritis Res. Ther., 19(1):93.
PMID: 28506283 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Sireesh et al. (2017), Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade J. Nutr. Biochem, 44(0):11-21.
PMID: 28343084 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySA Smith et al. (2017), The IL-1RI Co-Receptor TILRR (FREM1�Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease JACC Basic Transl Sci, 2(4):398-414.
PMID: 28920098 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Huang et al. (2017), Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway Cell Death Discov, 3(0):16097.
PMID: 28250969 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Muschaweck et al. (2017), IL-1? and IL-23 Promote Extrathymic Commitment of CD27(+)CD122(-) ?? T Cells to ??T17 Cells J. Immunol., 0(0).
PMID: 28855314 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoMX Li et al. (2017), Gene deficiency and pharmacological inhibition of caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs Mol. Psychiatry, 0(0).
PMID: 28416811 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Wang et al. (2017), Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells Sci Rep, 7(1):4880.
PMID: 28687790 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Makino et al. (2017), A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain Sci Rep, 7(1):16983.
PMID: 29208967 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Fu et al. (2017), Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1 J. Exp. Med., 0(0).
PMID: 28400474 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMarie-Laure Michel (2016), SLAM-associated protein favours the development of iNKT2 over iNKT17 cells Eur J Immunol, 0(0).
PMID: 27338553 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Overexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels PLoS ONE, 11(9):e0163735.
PMID: 27662193 -
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo(2016), NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis Sci Rep, 6(0):39075.
PMID: 27966619 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCN LaRock et al. (2016), IL-1? is an innate immune sensor of microbial proteolysis Sci Immunol, 1(2).
PMID: 28331908 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShweta Pasi (2016), Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response J Biol Chem, 291(23):12358-69.
PMID: 27022030 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLN Guthrie et al. (2016), Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses J. Biol. Chem., 291(30):15830-40.
PMID: 27226638 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury J Immunol, 0(0).
PMID: 27559050 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayStephen J Galli (2016), Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis J. Clin. Invest., 0(0).
PMID: 27820702 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoRichard P Ciavarra (2016), Early gene activation initiates neuroinflammation prior to VSV neuroinvasion: Impact on antiviral responses and sleep J. Neuroimmunol, 0(0).
PMID: 28041664 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis Sci Rep, 6(0):37977.
PMID: 27905482 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells J Immunol, 196(11):4731-8.
PMID: 27183613 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence Nature, 535(7612):440-3.
PMID: 27409807 -
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo(2016), TLR4-Upregulated IL-1? and IL-1RI Promote Alveolar Macrophage Pyroptosis and Lung Inflammation through an Autocrine Mechanism Sci Rep, 6(0):31663.
PMID: 27526865 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Epidermal RAF prevents allergic skin disease Elife, 5(0).
PMID: 27431613 -
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo(2016), NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis Sci Rep, 6(0):39075.
PMID: 27966619 -
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo(2016), Platelets Guide Leukocytes to Their Sites of Extravasation PLoS Biol, 14(5):e1002459.
PMID: 27152726 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySwaroop S et al. (2016), HSP60 plays a regulatory role in IL-1beta-induced microglial inflammation via TLR4-p38 MAPK axis. J Neuroinflammation, 13(1):27.
PMID: 26838598 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCaiazzo M et al. (2015), Direct conversion of fibroblasts into functional astrocytes by defined transcription factors. Stem Cell Reports, 4(1):25-36.
PMID: 25556566 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoLiu X et al. (2015), Interleukin 1 type 1 receptor restore: a genetic mouse model for studying interleukin 1 receptor-mediated effects in specific cell types. J Neurosci, 35(7):2860-70.
PMID: 25698726 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBasu R et al. (2015), IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat Immunol, 16(3):286-95.
PMID: 25642823 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHu M et al. (2015), TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. J Immunol, 195(9):4415-25.
PMID: 26392463 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCowardin C et al. (2015), Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile. MBio, 6(1).
PMID: 25626905 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAnnemann M et al. (2015), IkappaBNS regulates murine Th17 differentiation during gut inflammation and infection. J Immunol, 194(6):2888-98.
PMID: 25694610 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDunne A et al. (2015), A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine. Mucosal Immunol, 8(3):607-17.
PMID: 25315966 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySchwinge D et al. (2015), Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis. J Immunol, 194(6):2522-30.
PMID: 25672751 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMarquard J et al. (2015), Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. Nat Med, 21(4):363-72.
PMID: 25774850 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJana M et al. (2014), Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis. Immunology, 141(4):549-63.
PMID: 24224652 -
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western BlotBakker P et al. (2014), A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion. Am J Pathol, 184(7):2013-22.
PMID: 24823805 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGrabiner M et al. (2014), Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2alpha. J Immunol, 193(3):1459-67.
PMID: 24990083 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayValcarcel M et al. (2014), IL-18 regulates melanoma VLA-4 integrin activation through a Hierarchized sequence of inflammatory factors. J Invest Dermatol, 134(2):470-80.
PMID: 23938462 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMoon C et al. (2014), Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis. Mucosal Immunol, 7(4):818-28.
PMID: 24220295 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTamiya H et al. (2014), IFN-gamma or IFN-alpha ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex. J Immunol, 192(8):3793-804.
PMID: 24634492 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA (Standard)Ingham V et al. (2014), Glimepiride reduces CD14 expression and cytokine secretion from macrophages. J Neuroinflammation, 11(0):115.
PMID: 24952384 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJin et al. (2014), Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells. PLoS ONE, 9(12):e115981.
PMID: 25535736 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKomatsu N et al. (2014), Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat Med, 20(1):62-8.
PMID: 24362934 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLutz A et al. (2014), Interleukin-1beta enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes. PLoS ONE, 9(12):e115603.
PMID: 25551609 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAkiyama T et al. (2014), Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-alpha and interleukin-1beta but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gingipain. J Biol Chem, 289(22):15621-30.
PMID: 24755218 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHahn W et al. (2014), Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics. Am J Physiol Endocrinol Metab, 306(9):E1033-45.
PMID: 24595304 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGlenn J et al. (2014), Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis. Stem Cells, 32(10):2744-55.
PMID: 24911892 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBlum B et al. (2014), Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway. Elife, 3(0):e02809.
PMID: 25233132 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNeumann C et al. (2014), Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med, 211(9):1807-19.
PMID: 25073792 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySteelman A et al. (2014), Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis. J Biol Chem, 288(33):23776-87.
PMID: 23836896 -
Halai et al. (2014), ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo. J Cell Sci, 127(0):620-9.
PMID: 24317296 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySchmid M et al. (2013), PI3-kinase gamma promotes Rap1a-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth. PLoS ONE, 8(4):e60226.
PMID: 23565202 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureLee S et al. (2013), Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-kappaB pathway and attenuating ROS production. PLoS ONE, 8(12):e80873.
PMID: 24324641 -
Species: Mouse
Sample Types: In Vivo
Applications: In vivoSong J et al. (2013), In vivo processing of CXCL5 (LIX) by matrix metalloproteinase (MMP)-2 and MMP-9 promotes early neutrophil recruitment in IL-1beta-induced peritonitis. J Immunol, 190(1):401-10.
PMID: 23225890 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJayaraman P et al. (2013), IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation. J Immunol, 190(8):4196-204.
PMID: 23487424 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayZehendner et al. (2013), A novel in vitro model to study pericytes in the neurovascular unit of the developing cortex. PLoS ONE, 8(11):e81637.
PMID: 24278454 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBruchard M et al. (2012), Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med, 19(1):57-64.
PMID: 23202296 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhao H et al. (2012), Age-Dependent Neuroimmune Modulation of IGF-1R in the Traumatic Mice. Immun Ageing, 9(1):12.
PMID: 22640633 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu N et al. (2012), Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression. Mol. Endocrinol., 26(5):775-85.
PMID: 22474109 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoDubin PJ et al. (2012), Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection. Infect. Immun., 80(1):398-409.
PMID: 22025517 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoQuinton LJ et al. (2012), Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice. J. Clin. Invest., 122(5):1758-63.
PMID: 22466650 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012), Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J. Exp. Med., 209(8):1505-17.
PMID: 22802353 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFlanagan K et al. (2012), Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS. PLoS ONE, 7(7):e40443.
PMID: 22792325 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoProebstl D et al. (2012), Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J. Exp. Med., 209(6):1219-34.
PMID: 22615129 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012), Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A, 109(25):9971-6.
PMID: 22665806 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMa Y et al. (2011), Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J. Exp. Med., 208(3):491-503.
PMID: 21383056 -
Species: Mouse
Sample Types: Buffer
Applications: Binding AssayOwyang AM et al. (2011), XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1beta-mediated diseases. MAbs, 3(1):49-60.
PMID: 21048425 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoSanchez-Alavez M et al. (2011), Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors. J. Biol. Chem., 286(17):14983-90.
PMID: 21330367 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoPetri B et al. (2011), Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo. Blood, 117(3):942-52.
PMID: 21030556 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayEl-Behi M et al. (2011), The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat. Immunol., 12(6):568-75.
PMID: 21516111 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoChou RC et al. (2010), Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis. Immunity, 33(2):266-78.
PMID: 20727790 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCho JS et al. (2010), IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J. Clin. Invest., 120(5):1762-73.
PMID: 20364087 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoAden U et al. (2010), Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept. Brain Behav. Immun., 24(5):747-58.
PMID: 19861157 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: BioassayJayaraman P et al. (2010), Tim3 binding to galectin-9 stimulates antimicrobial immunity. J. Exp. Med., 207(11):2343-54.
PMID: 20937702 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKayamuro H et al. (2010), Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J. Virol., 84(24):12703-12.
PMID: 20881038 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoGrossberg AJ et al. (2010), Arcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130. Endocrinology, 151(2):606-16.
PMID: 20016025 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGhiringhelli F et al. (2009), Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med., 15(10):1170-8.
PMID: 19767732 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen X et al. (2009), Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway. J. Immunol., 183(10):6135-44.
PMID: 19841165 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOhno T et al. (2009), Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J. Immunol., 183(12):7890-7.
PMID: 19933859 -
Species: N/A
Sample Types: N/A
Applications: Western BlotMartin U et al. (2009), Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages. J. Immunol., 183(6):4021-30.
PMID: 19717513 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoMizutani N et al. (2009), Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice. J. Immunol., 183(6):4039-46.
PMID: 19684087 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoNilsberth C et al. (2009), The role of interleukin-6 in lipopolysaccharide-induced fever by mechanisms independent of prostaglandin E2. Endocrinology, 150(4):1850-60.
PMID: 19022895 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKoziczak-Holbro M et al. (2009), The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation. Arthritis Rheum., 60(6):1661-71.
PMID: 19479877 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOhba T et al. (2008), A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs. Arthritis Rheum., 58(11):3510-9.
PMID: 18975342 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoScarlett JM et al. (2008), Regulation of agouti-related protein messenger ribonucleic acid transcription and peptide secretion by acute and chronic inflammation. Endocrinology, 149(10):4837-45.
PMID: 18583425 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHudson CA et al. (2008), Induction of IL-33 expression and activity in central nervous system glia. J. Leukoc. Biol., 84(3):631-43.
PMID: 18552204 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoCostelloe C et al. (2008), IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8. J. Neurochem., 105(5):1960-9.
PMID: 18284608 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoWu CC et al. (2008), In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model. Cell. Immunol., 251(2):78-85.
PMID: 18495099 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBujak M et al. (2008), Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. Am. J. Pathol., 173(1):57-67.
PMID: 18535174 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoOlivadoti MD et al. (2008), Effects of i.c.v. administration of interleukin-1 on sleep and body temperature of interleukin-6-deficient mice. Neuroscience, 153(1):338-48.
PMID: 18367337 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoAntonopoulos C et al. (2007), IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. J. Leukoc. Biol., 83(2):361-7.
PMID: 17984289 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLi W et al. (2007), Protection of CD8+ T cells from activation-induced cell death by IL-18. J. Leukoc. Biol., 82(1):142-51.
PMID: 17400610 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKang YJ et al. (2007), Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages. Nat. Immunol., 8(6):601-9.
PMID: 17496895 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShchors K et al. (2006), The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta. Genes Dev., 20(18):2527-38.
PMID: 16980582 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Osuchowski MF et al. (2006), Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J. Immunol., 177(3):1967-74.
PMID: 16849510 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoVickers TA et al. (2006), Modification of MyD88 mRNA splicing and inhibition of IL-1beta signaling in cell culture and in mice with a 2'-O-methoxyethyl-modified oligonucleotide. J. Immunol., 176(6):3652-61.
PMID: 16517734 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHaraguchi G et al. (2006), A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model. J. Mol. Cell. Cardiol., 41(5):885-92.
PMID: 16963076 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Penido C et al. (2006), Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice. Inflamm. Res., 55(11):457-64.
PMID: 17122962 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMendez MP et al. (2006), Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol., 290(5):L962-70.
PMID: 16373671 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Osuchowski MF et al. (2005), Sequential ELISA to profile multiple cytokines from small volumes. J. Immunol. Methods, 302(1):172-81.
PMID: 16023134 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoPerrin FE et al. (2005), Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration. Brain, 128(0):854-66.
PMID: 15689362 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoChing S et al. (2005), IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system. Brain Behav. Immun., 19(2):127-37.
PMID: 15664785 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoOjaniemi M et al. (2005), TLR-2 is upregulated and mobilized to the hepatocyte plasma membrane in the space of Disse and to the Kupffer cells TLR-4 dependently during acute endotoxemia in mice. Immunol. Lett., 102(2):158-68.
PMID: 16216339 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Ellaban E et al. (2004), Selective macrophage suppression during sepsis. Cell. Immunol., 231(1):103-11.
PMID: 15919375
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Customer Reviews for Recombinant Mouse IL-1 beta/IL-1F2 Protein (7)
Customer Images
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 10/05/2020
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Application: Stem/Immune cell maintenance or differentiationReason for Rating: Good for Th17 DifferentiationVerified Customer | Posted 03/17/2020
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Application: In vivo studyVerified Customer | Posted 03/06/2020
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 01/15/2020
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Application: Inflammatory stimulantReason for Rating: Primary mouse fibroblasts were treated with IL1b for 24 hours. The supernatant was collected and analyzed for IL-6.Verified Customer | Posted 12/15/2017
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 08/02/2017
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Application: Apoptosis assayReason for Rating: I have a good apoptosis resultsVerified Customer | Posted 01/13/2016I treat the IL-1 beta with IFN-gamma in beta-Tc3 cells.Cell death rate is almost 30% for 48 hrs.
There are no reviews that match your criteria.
FAQs for Recombinant Mouse IL-1 beta/IL-1F2 Protein
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Does IL-1 beta induce NO in smooth muscle?
Yes it does, based on the literature.
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Can Recombinant Mouse IL-1 beta/IL-1F2 Protein (Catalog # 401-ML) be used in rat or human cells?
Bioactivity of Recombinant Mouse IL-1 beta Protein (Catalog # 401-ML) has only been evaluated using mouse cells. We offer both Recombinant Human IL-1 beta Protein (Catalog # 201-IL) and Recombinant Rat IL-1 beta Protein (Catalog # 501-RL) that we recommend for use in human and rat assay systems.