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IL-1 beta/IL-1F2: Simple Plex

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

7 results for "IL-1 beta/IL-1F2 Simple Plex" in Products

IL-1 beta/IL-1F2: Simple Plex

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

7 results for "IL-1 beta/IL-1F2 Simple Plex" in Products

Simple Plex 16x4 Panel including IFN-y 3rd gen, IL-6 2nd gen, IL-8, and TNF-a 2nd gen

Simple Plex Cartridge Kit for quantitation of IL-1 beta. Includes wash buffer and sample diluent SD13. For use with the Ella automated immunoassay system.

Simple Plex Cartridge Kit for quantitation of IL-1 beta. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Catalog #: 894962

Control for use with Human IL-1 beta/IL-1F2 Simple Plex Cartridge Kit

Simple Plex 16x6 Panel including IL-1b, IL-12 p70, IL-10, IL-2, IFNg 3rd gen, TNF-a 2nd gen, IL-4 2nd gen, and IL-6 2nd gen

Catalog #: 898634

Control for use with Mouse IL-1 beta/IL-1F2 Simple Plex Cartridge Kit

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