7 results for "YAP1 Small Molecules and Peptides" in Products
YAP1: Small Molecules and Peptides
The transcriptional coactivator Yes-associated protein (YAP), also known as Yes-associated protein 1 (YAP1), Yes-Associated Protein YAP65 Homolog, Protein Yorkie Homolog and YAP65 has a theoretical molecular weight of 65 kDa. The YAP1 gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. YAP1 shares homology with the WW domain of transcriptional co-activator with PDZ-binding motif (TAZ), which functions as a transcriptional ...
Potent and selective LATS inhibitor; activates YAP signaling
| Chemical Name: | N-[4-[(3R)-Piperidin-3-yl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridin-4-amine |
| Purity: | ≥98% (HPLC) |
YAP inhibitor
| Alternate Names: | Visudyne |
| Chemical Name: | (4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester |
| Purity: | ≥95% (HPLC) |
YAP inhibitor
| Purity: | ≥95% (HPLC) |
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling
| Chemical Name: | 4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide |
| Purity: | ≥98% (HPLC) |
Geranylgeranyltransferase-I (GGTase-I) inhibitor
| Chemical Name: | (2R)-3,3,3-Trifluoro-2-methoxy-1-[(7R)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent pan-TEAD inhibitor
| Chemical Name: | N-[(1S)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective MST1/2 inhibitor; orally bioavailable
| Chemical Name: | 4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
