VHL Ligands Plus Linker Building Blocks: Small Molecules and Peptides

VH 032 amide-alkylC7-amine

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C7-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(8-Aminooctanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-PEG3-BCN

Catalog #: 8123

Product Documents

Functionalized VHL building block for copper-free click chemistry

Chemical Name:	((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl ((S)-14-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-15,15-dimethyl-12-oxo-3,6,9-trioxa-13-azahexadecyl)carbamate
Purity:	≥90% (HPLC)

VH 032 amide-PEG2-amine

Catalog #: 6907

Product Documents

VHL ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-PEG2-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity:	≥95% (HPLC)

VH 032 amide-PEG3-amine

Catalog #: 6463

Citations (1)

Product Documents

VHL ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-PEG3-NH₂
Chemical Name:	(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-PEG1-amine

Catalog #: 6879

Product Documents

VHL ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-PEG1-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(2-(2-Aminoethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC4-acid

Catalog #: 6680

Product Documents

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C4-COOH
Chemical Name:	6-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-6-oxohexanoic acid
Purity:	≥95% (HPLC)

VH 032 amide-PEG5-acid

Catalog #: 7105

Product Documents

VHL ligand with PEG linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-PEG5-COOH
Chemical Name:	(S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosanoic acid
Purity:	≥95% (HPLC)

VH 032 amide-alkylC8-amine

Catalog #: 6890

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C8-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(9-Aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-PEG4-amine

Catalog #: 6464

Product Documents

VHL ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-PEG4-NH₂
Chemical Name:	(2S,4R)-1-((S)-17-Amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC4-amine

Catalog #: 6465

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C4-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC2-amine

Catalog #: 6852

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C2-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC2-acid

Catalog #: 7106

Product Documents

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C2-COOH
Chemical Name:	4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid
Purity:	≥95% (HPLC)

VH 101 phenol-alkylC4-amine

Catalog #: 7293

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name:	(2S,4R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 101 phenol-alkylC6-amine

Catalog #: 7294

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name:	(2S,4R)-N-(2-((6-Aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-PEG6-amine

Catalog #: 7568

Product Documents

VHL ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-PEG6-NH₂
Chemical Name:	(2S,4R)-1-((S)-23-Amino-2-(tert-butyl)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC9-amine

Catalog #: 7566

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C9-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(10-Aminodecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-PEG2-acid

Catalog #: 7214

Product Documents

VHL ligand with PEG linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-PEG2-COOH
Chemical Name:	3-(2-(3-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)ethoxy)propanoic acid
Purity:	≥95% (HPLC)

VH 032 amide-alkylC6-amine

Catalog #: 6853

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	VH 032 - linker 8,(_S,R,S)-AHPC-C2-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(7-Aminoheptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC10-amine

Catalog #: 6880

Citations (2)

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C10-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(11-Aminoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC3-amine

Catalog #: 7073

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C3-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(4-Aminobutanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC3-acid

Catalog #: 7216

Product Documents

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C3-COOH
Chemical Name:	5-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid
Purity:	≥95% (HPLC)

VH 032 amide-alkylC5-acid

Catalog #: 7217

Product Documents

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C5-COOH
Chemical Name:	7-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptanoic acid
Purity:	≥95% (HPLC)

VH 032 phenol-alkylC4-amine

Catalog #: 6909

Citations (1)

Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	(S,R,S)-AHPC-phenol-C4-NH2
Chemical Name:	(2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-(4-aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)

VH 032 amide-alkylC6-acid

Catalog #: 7107

Product Documents

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C6-COOH
Chemical Name:	8-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-8-oxooctanoic acid
Purity:	≥95% (HPLC)

VH 032 amide-alkylC9-acid

Catalog #: 7404

Citations (1)

Product Documents

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names:	(S,R,S)-AHPC-C9-COOH
Chemical Name:	11-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecanoic acid
Purity:	≥95% (HPLC)

VHL Ligands Plus Linker Building Blocks: Small Molecules and Peptides

VH 032 amide-alkylC7-amine

VH 032 amide-PEG3-BCN

VH 032 amide-PEG2-amine

VH 032 amide-PEG3-amine

VH 032 amide-PEG1-amine

VH 032 amide-alkylC4-acid

VH 032 amide-PEG5-acid

VH 032 amide-alkylC8-amine

VH 032 amide-PEG4-amine

VH 032 amide-alkylC4-amine

VH 032 amide-alkylC2-amine

VH 032 amide-alkylC2-acid

VH 101 phenol-alkylC4-amine

VH 101 phenol-alkylC6-amine

VH 032 amide-PEG6-amine

VH 032 amide-alkylC9-amine

VH 032 amide-PEG2-acid

VH 032 amide-alkylC6-amine

VH 032 amide-alkylC10-amine

VH 032 amide-alkylC3-amine

VH 032 amide-alkylC3-acid

VH 032 amide-alkylC5-acid

VH 032 phenol-alkylC4-amine

VH 032 amide-alkylC6-acid

VH 032 amide-alkylC9-acid

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