VH 032 amide-alkylC5-amine
Tocris Bioscience, part of Bio-Techne | Catalog # 6985
VHL ligand with alkyl linker and terminal amine for onward chemistry
Key Product Details
Description
VHL ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names
(S,R,S)-AHPC-C5-NH2
Product Description
VH 032 amide-alkylC5-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.This product has been recently renamed. The previous name for this product was VH 032 - linker 13
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
616.64
Formula
C28H41N5O4S.2HCl
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2S,4R)-1-((S)-2-(6-Aminohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
CAS Number
2415256-20-9
InChI Key
QJAHMRABVVCVFO-OTCWRJAQSA-N
SMILES
CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCCCCN)=O)=O)O)=O)SC=N1.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
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Product Specific Notices for VH 032 amide-alkylC5-amine
For research use only
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