VH 032 amide-alkylC5-azide
Tocris Bioscience, part of Bio-Techne | Catalog # 7867
VHL ligand with alkylC5 linker and terminal azide for onward chemistry
Key Product Details
Description
VHL ligand with alkylC5 linker and terminal azide for onward chemistry
Product Description
VH 032 amide-alkylC5-azide is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC5 linker and terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
569.73
Formula
C28H39N7O4S
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2S,4R)-1-((S)-2-(6-Azidohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CAS Number
2821804-11-7
InChI Key
FKUOHRQDBXOUQK-OTNCWRBYSA-N
SMILES
O=C(CCCCCN=[N+]=[N-])N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
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Product Specific Notices for VH 032 amide-alkylC5-azide
For research use only
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