VH 032 amide-PEG5-acid
Tocris Bioscience, part of Bio-Techne | Catalog # 7105
VHL ligand with PEG linker and terminal acid for onward chemistry
Key Product Details
Description
VHL ligand with PEG linker and terminal acid for onward chemistry
Alternative Names
(S,R,S)-AHPC-PEG5-COOH
Product Description
VH 032 amide-PEG5-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
750.91
Formula
C36H54N4O11S
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosanoic acid
CAS Number
2172820-14-1
PubChem ID
134184001
InChI Key
YDOJYEPMGKGKQV-ZLWRCJDJSA-N
SMILES
CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCOCCOCCOCCOCCOCCC(O)=O)=O)=O)O)=O)SC=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
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Product Specific Notices for VH 032 amide-PEG5-acid
For research use only
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