399 results for "VEGFR3/Flt-4" in Products
VEGFR3/Flt-4 Products
VEGFR1 (Flt-1), VEGFR2 (KDR/Flk-1), and VEGFR3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGFR2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGFR3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
Potent VEGFR-1, -2 and -3 inhibitor
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
Dual site Src kinase inhibitor