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VEGFR3/Flt-4 Products
VEGFR1 (Flt-1), VEGFR2 (KDR/Flk-1), and VEGFR3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGFR2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGFR3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
33 results for "VEGFR3/Flt-4" in Products
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VEGFR3/Flt-4 Products
VEGFR1 (Flt-1), VEGFR2 (KDR/Flk-1), and VEGFR3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGFR2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGFR3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
33 results for "VEGFR3/Flt-4" in Products
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Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names : | SU 11248 |
| Chemical Name : | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity : | ≥99% (HPLC) |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
| Chemical Name : | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity : | ≥98% (HPLC) |
1 vial each of PE-conjugated anti-VEGF R1 (clone 49560), VEGF R2 (clone 89106), and VEGF R3 (clone 54733)
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #89106, 49560, 54733 |
| Applications : | Flow Cytometry |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names : | Semaxinib |
| Chemical Name : | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity : | ≥99% (HPLC) |
Biotinylated
| Source : | HEK293 |
| Accession # : | P35916.3 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P35916 |
| Applications : | Binding Activity |
Potent VEGFR-1, -2 and -3 inhibitor
| Chemical Name : | N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide |
| Purity : | ≥99% (HPLC) |
Potent inhibitor of VEGFR, PDGFR and FGFR
| Chemical Name : | 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #102804 |
| Applications : | ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #102806 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #54733 |
| Applications : | ELISA Detection, Flow Cytometry |
| Source : | Sf 21 (baculovirus) |
| Accession # : | P35917 |
| Applications : | Binding Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #54703 |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #54716 |
| Applications : | ELISA Capture |
