Sign In / Register
TrkB Products
Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.
32 results for "TrkB" in Products
Search
Application
Product Action
Conjugates
Clonality
Host Species
Isotype
Low Endotoxin
Sample Size
Citations
Reviews
TrkB Products
Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.
32 results for "TrkB" in Products
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunohistochemistry, Simple Western, Western Blot |
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
TrkB receptor antagonist
| Chemical Name : | N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide |
| Purity : | ≥99% (HPLC) |
| Source : | NS0 |
| Accession # : | Q16620.1 |
| Applications : | Bioactivity |
TrkB receptor antagonist
| Purity : | ≥95% (HPLC) |
TrkB agonist
| Alternate Names : | 7,8-DHF |
| Chemical Name : | 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one |
| Purity : | ≥98% (HPLC) |
| Assay Range : | 93.8 - 6,000 pg/mL |
| Applications : | ELISA |
Selective TrkB receptor agonist; neuroprotectant
| Chemical Name : | N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #72509 |
| Applications : | Flow Cytometry |
| Source : | NS0 |
| Accession # : | P15209 |
| Applications : | Bioactivity |
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
| Chemical Name : | N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea |
| Purity : | ≥98% (HPLC) |
TrkB and TrkC agonist; brain penetrant
| Chemical Name : | 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #225105 |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Simple Western, Western Blot |
Potent TrkB agonist
| Chemical Name : | N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #72509 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #72509 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #72509 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #75133 |
| Applications : | Immunohistochemistry, Western Blot |
