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TIM-1/KIM-1/HAVCR Products
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
69 results for "TIM-1/KIM-1/HAVCR" in Products
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TIM-1/KIM-1/HAVCR Products
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
69 results for "TIM-1/KIM-1/HAVCR" in Products
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Catalog #:
SPCK-PANEL
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Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ELISA
| Sensitivity : | 0.046 ng/mL |
| Assay Range : | 0.156 - 10 ng/mL (Urine) |
| Applications : | ELISA |
WB, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Capture, Immunohistochemistry, Western Blot |
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
ELISA
| Sensitivity : | 3.63 pg/mL |
| Assay Range : | 10.9 - 700 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
WB, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
Catalog #:
SPCKB-PS-002900
Simple Plex Cartridge Kit for quantitation of TIM-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
ELISA
| Sensitivity : | 2.18 pg/mL |
| Assay Range : | 7.81 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
WB, Flow, IHC, CyTOF-ready
Clone 219211 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #219211 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
BA
| Source : | NS0 |
| Accession # : | AAC39862 |
| Applications : | Bioactivity |
Catalog #:
ARY019
Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies
ELISA
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
Catalog #:
SPCKB-RP-000548
Simple Plex Cartridge Kit for quantitation of TIM-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
ELISA
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #222414 |
| Applications : | Flow Cytometry |
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #222414 |
| Applications : | ELISA Capture, Western Blot |
Catalog #:
11157-TM
BA
| Source : | HEK293 |
| Accession # : | Q96D42.3 |
| Applications : | Bioactivity |
