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TIM-1/KIM-1/HAVCR Products

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

65 results for "TIM-1/KIM-1/HAVCR" in Products

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TIM-1/KIM-1/HAVCR Products

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

65 results for "TIM-1/KIM-1/HAVCR" in Products

Simple Plex Cartridge Kit containing TIM-1 for use with Human CCS/Plasma/Serum/Urine. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

WB, Flow, IHC, CyTOF-ready

Clone 219211 was used by HLDA to establish CD designation

Simple Plex Cartridge Kit containing TIM-1 for use with Rat Plasma/Serum/Urine. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

WB
BA

Clone 219211 was used by HLDA to establish CD designation

BA
BA
Flow, IHC, CyTOF-ready

Recombinant Monoclonal Antibody.

Flow, CyTOF-ready
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