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TIM-1/KIM-1/HAVCR Products

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

69 results for "TIM-1/KIM-1/HAVCR" in Products

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TIM-1/KIM-1/HAVCR Products

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

69 results for "TIM-1/KIM-1/HAVCR" in Products

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies

Simple Plex Cartridge Kit for quantitation of TIM-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

WB, Flow, IHC, CyTOF-ready

Clone 219211 was used by HLDA to establish CD designation

Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies

Simple Plex Cartridge Kit for quantitation of TIM-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

BA

(268 aa)

Catalog #: RDC2695
BA
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