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Thrombopoietin/Tpo Products
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
25 results for "Thrombopoietin/Tpo" in Products
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Thrombopoietin/Tpo Products
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
25 results for "Thrombopoietin/Tpo" in Products
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
| Sensitivity : | 20 pg/mL |
| Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Citrate Plasma) |
| Applications : | ELISA |
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Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications : | ELISA |
Animal Free
| Source : | E. coli |
| Accession # : | NP_000451.1 |
| Applications : | Bioactivity |
Earn double rewards for reviews
| Source : | E. coli |
| Accession # : | NP_000451 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P40225 |
| Applications : | Bioactivity |
| Source : | Sf 21 (baculovirus) |
| Accession # : | P40225 |
| Applications : | Bioactivity |
| Sensitivity : | 18.5 pg/mL |
| Assay Range : | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Analyzed by SEC-MALS. His-tag (HEK-293-expressed)
| Source : | HEK293 |
| Accession # : | P40225.1 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P40226 |
| Applications : | Bioactivity |
| Source : | Sf 9 (baculovirus) |
| Accession # : | P40225 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #34817 |
| Applications : | Block/Neutralize, ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34863 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #378120 |
| Applications : | ELISA Capture, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Assay Range : | 93.8 - 6,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #34840 |
| Applications : | ELISA Detection |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Source : | NS0 |
| Accession # : | P49745 |
| Applications : | Bioactivity |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
