P2Y12/P2RY12: Small Molecules and Peptides
P2RY12 belongs to the family of G protein-coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. P2RY12 is highly expressed in platelets. It is expressed at lower levels in brain. P2RY12 is involved in platelet aggregation. It is a potential target for the treatment of thromboembolisms and other clotting disorders.
Products:
7 results for "P2Y12/P2RY12 Small Molecules and Peptides" in Products
7 results for "P2Y12/P2RY12 Small Molecules and Peptides" in Products
P2Y12/P2RY12: Small Molecules and Peptides
P2RY12 belongs to the family of G protein-coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. P2RY12 is highly expressed in platelets. It is expressed at lower levels in brain. P2RY12 is involved in platelet aggregation. It is a potential target for the treatment of thromboembolisms and other clotting disorders.
Products:
Highly potent P2Y12 antagonist
| Chemical Name: | 1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt |
| Purity: | ≥95% (HPLC) |
Potent agonist at P2Y1, P2Y12 and P2Y13
| Alternate Names: | 2-(Methylthio)adenosine 5'-diphosphate,2-Methylthio-ADP,MeSADP |
| Chemical Name: | 2-(Methylthio)adenosine-5'-(trihydrogen diphosphate) trisodium salt |
| Purity: | ≥98% (HPLC) |
Selective P2Y12 antagonist
| Alternate Names: | Plavix |
| Chemical Name: | (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogen sulfate |
| Purity: | ≥98% (HPLC) |
Selective P2Y12 antagonist
| Alternate Names: | Plavix |
| Chemical Name: | Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity P2Y12 antagonist
| Chemical Name: | Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate |
| Purity: | ≥98% (HPLC) |
Highly potent P2Y12 antagonist
| Alternate Names: | Cangrelor tetrasodium salt |
| Chemical Name: | N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]adenosine-5'-O-(β,γ-dichloromethylene)triphosphate tetrasodium salt |
| Purity: | ≥98% (HPLC) |
Potent PARP inhibitor
| Chemical Name: | N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamide hydrochloride |
| Purity: | ≥98% (HPLC) |
