PSB 0739
Tocris Bioscience, part of Bio-Techne | Catalog # 3983
Highly potent P2Y12 antagonist
Product Description
PSB 0739 is a highly potent P2Y12 receptor antagonist (Ki = 24.9 nM). Unlike clopidogrel (Cat. No. 2490), does not require bioactivation.Licensing Information
Sold with the permission of the University of Bonn.Product Specifications
Molecular Weight
609.54
Formula
C26H17N3Na2O8S2
Storage
Desiccate at RT
Purity
≥95% (HPLC)
Chemical Name
1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt
CAS Number
1052087-90-7
PubChem ID
44583582
InChI Key
QBLLYXXXOJUNCV-UHFFFAOYSA-L
SMILES
[Na+].[Na+].NC1=C(C=C(NC2=CC(=C(NC3=CC=CC=C3)C=C2)S([O-])(=O)=O)C2=C1C(=O)C1=CC=CC=C1C2=O)S([O-])(=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.24 | 25 |
Preparing Stock Solutions
for PSB 0739
The following data is based on the product molecular weight 609.54
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 6.56 mL | 32.81 mL | 65.62 mL |
| 1.25 mM | 1.31 mL | 6.56 mL | 13.12 mL |
| 2.5 mM | 0.66 mL | 3.28 mL | 6.56 mL |
| 12.5 mM | 0.13 mL | 0.66 mL | 1.31 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Baqi High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. J.Med.Chem. 2009 PMID: 19463000
- Felix Development of a comprehensive set of P2 receptor pharmacological research compounds. Purinerg.Sig. 2011 PMID: 22052555
- Hoffmann Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor. J.Pharmacol.Exp.Ther. 2009 PMID: 19690189
Product Specific Notices for PSB 0739
For research use only
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