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NFkB1 Products

NFkB1 (NFkB p50) and NFkB2 (NFkB p52) are class I members of the Rel/NFkB family of transcription factors that also includes RelA, c-Rel and RelB. Rel/NFkB members regulate expression of genes that participate in immune, apoptotic and oncogenic processes. Class I members lack a C-terminal transcriptional activation segment found in class II members, but contain an RHD (Rel homology domain) that mediates DNA binding, nuclear localization and dimerization. NFkB1 and NFkB2 105 and 100 kDa precursors are proteolytically cleaved to 50 and 52 kDa active subunits, respectively. NFkB is predominantly localized in the cytoplasm as a complex with inhibitory IkB proteins and is released and translocated to the nucleus after phosphorylation of IkB.

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154 results for "NFkB1" in Products

154 results for "NFkB1" in Products

NFkB1 Products

NFkB1 (NFkB p50) and NFkB2 (NFkB p52) are class I members of the Rel/NFkB family of transcription factors that also includes RelA, c-Rel and RelB. Rel/NFkB members regulate expression of genes that participate in immune, apoptotic and oncogenic processes. Class I members lack a C-terminal transcriptional activation segment found in class II members, but contain an RHD (Rel homology domain) that mediates DNA binding, nuclear localization and dimerization. NFkB1 and NFkB2 105 and 100 kDa precursors are proteolytically cleaved to 50 and 52 kDa active subunits, respectively. NFkB is predominantly localized in the cytoplasm as a complex with inhibitory IkB proteins and is released and translocated to the nucleus after phosphorylation of IkB.

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Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, Simple Western
Western Blot: NFkB1/NFkB p105 AntibodyBSA Free [NBP1-77395]
(4)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF
NFkB1/NFkB p105 Antibody - BSA Free
(2)
Applications: ELISA
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #23GB2710
Applications: WB, ICC/IF, Flow, Mycoplasma
Applications: ELISA
Novus ELISA Kits
Results Per Page
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