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MG 132

Tocris Bioscience a Bio-Techne Brand

Calpain Inhibitors Small Molecule
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1748/5
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Key Product Details

Description: Proteasome and calpain inhibitor. Inhibits NF-κB activation
Alternative Names: Z-LLL-al, Z-Leu-Leu-Leu-CHO
Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
Purity: ≥95% (HPLC)
Molecular Weight: 475.63

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Citations for MG 132 (60)

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Customer Reviews for MG 132 (4)

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  • Inhibition of NF-kB activation
    Name: MARINA KOUTSIOUMPA
    Species: Human
    Assay Type: In Vitro
    MG 132 was used to block NF-kB activation and determine the pathway of a chemotherapeutic in pancreatic cancer lines. The inhibitor worked nicely, and the results were consistent
  • MG132
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: H9C2
    Treated H9C2 cells for 6hours to inhibit ubiquitination.
    MG 132 Serum 1748
  • MG-132 (15 µM)
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: LP-1 cell line
    Cells were treated with MG-132 (15 µM) for 18 hours in the absence or presence of GSK2656157 (10 µM)
    MG 132 Serum 1748
  • MG 132 Usage Information
    Name: Chao Li
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Human intestine subepithelial myofibroblasts
    It works well and dissolves perfectly in DMSO. I treated the cells with MG 132 (final concentration: 10 micromolar) in serum free medium for 24 hours.

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Product Documents for MG 132

Certificate of Analysis

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