MMR/CD206: Antibodies
MMR (macrophage mannose receptor), also known as MR, CD206, Mrc1, and CLEC13D, is an endocytic receptor that is expressed on M2 alternatively activated macrophages, tumor-associated macrophages (TAMs), inflammatory dendritic cells, and microvascular endothelial cells. MMR internalizes ligands in clathrin-coated vesicles and recycles to the cell surface. It binds LH (luteinizing hormone/lutropin), TSH (thyroid stimulating hormone/thyrotropin), collagens, lysosomal hydrolases, myeloperoxidase, chondroitin sulfates, sulfated N-acetylgalactosamines, and pathogenic microbial branched sugars with terminal mannose, fucose or N-acetylglucosamine. MMR is involved in T cell polarization and production of pro- and anti-inflammatory cytokines. It facilitates peptide presentation on MHC II and cross-presentation on MHC I which is important for tumor immunogenicity.
29 results for "MMR/CD206 Primary Antibodies" in Products
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MMR/CD206: Antibodies
MMR (macrophage mannose receptor), also known as MR, CD206, Mrc1, and CLEC13D, is an endocytic receptor that is expressed on M2 alternatively activated macrophages, tumor-associated macrophages (TAMs), inflammatory dendritic cells, and microvascular endothelial cells. MMR internalizes ligands in clathrin-coated vesicles and recycles to the cell surface. It binds LH (luteinizing hormone/lutropin), TSH (thyroid stimulating hormone/thyrotropin), collagens, lysosomal hydrolases, myeloperoxidase, chondroitin sulfates, sulfated N-acetylgalactosamines, and pathogenic microbial branched sugars with terminal mannose, fucose or N-acetylglucosamine. MMR is involved in T cell polarization and production of pro- and anti-inflammatory cytokines. It facilitates peptide presentation on MHC II and cross-presentation on MHC I which is important for tumor immunogenicity.
29 results for "MMR/CD206 Primary Antibodies" in Products
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #685645 |
Applications : | Immunohistochemistry, Simple Western, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #857615 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #309210 |
Applications : | Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #310301 |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #857615 |
Applications : | CyTOF-ready, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #857615 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #857615 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #857615 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #857615 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #857615 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #685641 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |