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MMR/CD206 Products

MMR (macrophage mannose receptor), also known as MR, CD206, Mrc1, and CLEC13D, is an endocytic receptor that is expressed on M2 alternatively activated macrophages, tumor-associated macrophages (TAMs), inflammatory dendritic cells, and microvascular endothelial cells. MMR internalizes ligands in clathrin-coated vesicles and recycles to the cell surface. It binds LH (luteinizing hormone/lutropin), TSH (thyroid stimulating hormone/thyrotropin), collagens, lysosomal hydrolases, myeloperoxidase, chondroitin sulfates, sulfated N-acetylgalactosamines, and pathogenic microbial branched sugars with terminal mannose, fucose or N-acetylglucosamine. MMR is involved in T cell polarization and production of pro- and anti-inflammatory cytokines. It facilitates peptide presentation on MHC II and cross-presentation on MHC I which is important for tumor immunogenicity.

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91 results for "MMR/CD206" in Products

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MMR/CD206 Products

MMR (macrophage mannose receptor), also known as MR, CD206, Mrc1, and CLEC13D, is an endocytic receptor that is expressed on M2 alternatively activated macrophages, tumor-associated macrophages (TAMs), inflammatory dendritic cells, and microvascular endothelial cells. MMR internalizes ligands in clathrin-coated vesicles and recycles to the cell surface. It binds LH (luteinizing hormone/lutropin), TSH (thyroid stimulating hormone/thyrotropin), collagens, lysosomal hydrolases, myeloperoxidase, chondroitin sulfates, sulfated N-acetylgalactosamines, and pathogenic microbial branched sugars with terminal mannose, fucose or N-acetylglucosamine. MMR is involved in T cell polarization and production of pro- and anti-inflammatory cytokines. It facilitates peptide presentation on MHC II and cross-presentation on MHC I which is important for tumor immunogenicity.

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91 results for "MMR/CD206" in Products

WB, Flow, IHC, CyTOF-ready
WB, Simple Western, IHC, ICC
ELISA, ICC/IF, IHC, WB
Flow, ICC/IF, IHC, WB
WB, Simple Western, IHC
Flow, CyTOF-ready
WB, Flow, CyTOF-ready
ICC/IF, WB

Recombinant Monoclonal Antibody.

Flow, Func, ICC/IF, IHC, IP, WB
Catalog #: BAF2534
WB
Catalog #: FAB25351N
Flow
Catalog #: FAB25351T
Flow
Catalog #: FAB25342U
Flow
Catalog #: FAB25342T
Flow
WB
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