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MMP-9 Products
MMP-9 (Gelatinase B) is a metalloproteinase that degrades multiple extracellular matrix components including Gelatin, Collagens III, IV, V, and XI, Elastin, Nidogen-1, and Vitronectin. It also cleaves a variety of chemokines and growth factors (e.g. IL-1 beta, CXCL8/IL-8, CXCL7, CXCL4, CXCL1, Latent TGF-beta, membrane bound TNF-alpha, VEGF, and FGF basic), Amyloid beta peptide, Substance P, and Myelin Basic Protein. MMP-9 can trigger signaling through various transmembrane proteins or inhibit signaling by inducing their shedding from the cell surface (e.g. CD44, E-Cadherin, Integrins, ICAM-1, and CD25/IL-2 R alpha). The activity of MMP-9 is regulated by its association with the TIMP-1 protease inhibitor. Circulating levels of MMP-9 are elevated in many inflammatory disorders including intraluminal thrombus formation, atherosclerosis, Crohn’s disease, hepatitis C virus infection, colorectal cancer, and Duchenne muscular dystrophy.
50 results for "MMP-9" in Products
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MMP-9 Products
MMP-9 (Gelatinase B) is a metalloproteinase that degrades multiple extracellular matrix components including Gelatin, Collagens III, IV, V, and XI, Elastin, Nidogen-1, and Vitronectin. It also cleaves a variety of chemokines and growth factors (e.g. IL-1 beta, CXCL8/IL-8, CXCL7, CXCL4, CXCL1, Latent TGF-beta, membrane bound TNF-alpha, VEGF, and FGF basic), Amyloid beta peptide, Substance P, and Myelin Basic Protein. MMP-9 can trigger signaling through various transmembrane proteins or inhibit signaling by inducing their shedding from the cell surface (e.g. CD44, E-Cadherin, Integrins, ICAM-1, and CD25/IL-2 R alpha). The activity of MMP-9 is regulated by its association with the TIMP-1 protease inhibitor. Circulating levels of MMP-9 are elevated in many inflammatory disorders including intraluminal thrombus formation, atherosclerosis, Crohn’s disease, hepatitis C virus infection, colorectal cancer, and Duchenne muscular dystrophy.
50 results for "MMP-9" in Products
| Sensitivity : | 0.156 ng/mL |
| Assay Range : | 0.312 - 20 ng/mL (Cell Culture Supernates, Serum, Platelet-poor Heparin Plasma, Saliva, Urine) |
| Applications : | ELISA |
Simple Plex Human MMP-9 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
| Source : | CHO |
| Accession # : | P14780 |
| Applications : | Enzyme Activity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Simple Western, Western Blot |
| Sensitivity : | 0.014 ng/mL |
| Assay Range : | 0.078 - 5 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma) |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Sensitivity : | 14 pg/mL |
| Assay Range : | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma) |
| Applications : | ELISA |
| Sensitivity : | 0.028 ng/mL |
| Assay Range : | 0.156 - 10 ng/mL |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | P41245 |
| Applications : | Enzyme Activity |
Contains Mercury, Dispose According to Local, State or Federal Laws.
| Sensitivity : | 0.01 pg/mL |
| Assay Range : | 0.25 - 16 pg/mL |
For use with catalog numbers DMP900, SMP900, PDMP900
| Applications : | Control, ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #4H3 |
| Applications : | CyTOF-ready, Immunohistochemistry, Immunoprecipitation, Western Blot |
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #36020 |
| Applications : | ELISA Capture, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
| Assay Range : | 78.1 - 5,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #56129 |
| Applications : | Flow Cytometry |
