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MMP-9 Products

MMP-9 (Gelatinase B) is a metalloproteinase that degrades multiple extracellular matrix components including Gelatin, Collagens III, IV, V, and XI, Elastin, Nidogen-1, and Vitronectin. It also cleaves a variety of chemokines and growth factors (e.g. IL-1 beta, CXCL8/IL-8, CXCL7, CXCL4, CXCL1, Latent TGF-beta, membrane bound TNF-alpha, VEGF, and FGF basic), Amyloid beta peptide, Substance P, and Myelin Basic Protein. MMP-9 can trigger signaling through various transmembrane proteins or inhibit signaling by inducing their shedding from the cell surface (e.g. CD44, E-Cadherin, Integrins, ICAM-1, and CD25/IL-2 R alpha). The activity of MMP-9 is regulated by its association with the TIMP-1 protease inhibitor. Circulating levels of MMP-9 are elevated in many inflammatory disorders including intraluminal thrombus formation, atherosclerosis, Crohn’s disease, hepatitis C virus infection, colorectal cancer, and Duchenne muscular dystrophy.

51 results for "MMP-9" in Products

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MMP-9 Products

MMP-9 (Gelatinase B) is a metalloproteinase that degrades multiple extracellular matrix components including Gelatin, Collagens III, IV, V, and XI, Elastin, Nidogen-1, and Vitronectin. It also cleaves a variety of chemokines and growth factors (e.g. IL-1 beta, CXCL8/IL-8, CXCL7, CXCL4, CXCL1, Latent TGF-beta, membrane bound TNF-alpha, VEGF, and FGF basic), Amyloid beta peptide, Substance P, and Myelin Basic Protein. MMP-9 can trigger signaling through various transmembrane proteins or inhibit signaling by inducing their shedding from the cell surface (e.g. CD44, E-Cadherin, Integrins, ICAM-1, and CD25/IL-2 R alpha). The activity of MMP-9 is regulated by its association with the TIMP-1 protease inhibitor. Circulating levels of MMP-9 are elevated in many inflammatory disorders including intraluminal thrombus formation, atherosclerosis, Crohn’s disease, hepatitis C virus infection, colorectal cancer, and Duchenne muscular dystrophy.

51 results for "MMP-9" in Products

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Simple Plex Human MMP-9 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies

Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies

Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors

Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies

Contains Mercury, Dispose According to Local, State or Federal Laws.

WB, IHC, IP, ICC
WB, Simple Western, IHC, IP, ICC

Pro-MMP9 activation inhibitor

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