Human MMP-9 Quantikine ELISA Kit

Name: Human MMP-9 Quantikine ELISA Kit
Brand: R&D Systems
SKU: DMP900
Rating: 5 (9 reviews)

R&D Systems, Inc. a Bio-Techne Brand

Catalog # DMP900

Citations (208)

(9)

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Setting the standard in quality research reagents

Key Product Details

Assay Length:	3.5 hours
Sample Type & Volume Required Per Well:	Cell Culture Supernates (10 uL), Serum (10 uL), Platelet-poor Heparin Plasma (10 uL), Saliva (10 uL), Urine (100 uL)
Sample Types:	Cell Culture Supernates, Serum, Platelet-poor Heparin Plasma, Saliva, Urine
Sensitivity:	0.156 ng/mL
Assay Range:	0.312 - 20 ng/mL (Cell Culture Supernates, Serum, Platelet-poor Heparin Plasma, Saliva, Urine)
Human MMP-9 Quantikine ELISA Kit Summary:	The Quantikine Human MMP-9 Immunoassay is a 3.5 hour solid phase ELISA designed to measure MMP-9 (92 kDa pro- and 82 kDa active forms but not the 65 kDa form) in cell culture supernates, saliva, serum, plasma, and urine. It is calibrated with CHO cell-expressed recombinant human pro-MMP-9 and the antibodies were raised against the recombinant factor. Natural human MMP-9 showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards, indicating that this kit can be used to determine relative mass values of natural human MMP-9.

View Full Technical Details for Human MMP-9 Quantikine ELISA Kit

Product Specifications for Human MMP-9 Quantikine ELISA Kit

Assay Type	Solid Phase Sandwich ELISA
Format	96-well strip plate
Measurement	Quantitative ELISA
Detection Method	Colorimetric - 450nm (TMB)
Conjugate	HRP
Reactivity	Human
Specificity	Natural and recombinant human 92 kDa Pro-MMP-9 and the 82 kDa active MMP-9
Cross-reactivity	< 0.5% cross-reactivity observed with available related molecules. < 50% cross-species reactivity observed with species tested.
Interference	Interference observed with 1 or more available related molecules.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision

Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum, Platelet-poor Heparin Plasma, Saliva, Urine

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	40	40	40
Mean (ng/mL)	0.833	2.04	11	0.972	2.35	12.2
Standard Deviation	0.017	0.039	0.316	0.077	0.184	0.845
CV%	2	1.9	2.9	7.9	7.8	6.9

Recovery

The recovery of Pro-MMP-9 spiked to three levels throughout the range of the assay was evaluated.

Sample Type	Average % Recovery	Range %
Cell Culture Media (n=5)	97	85-104
Platelet-poor Heparin Plasma (n=5)	96	89-108
Saliva (n=4)	90	74-114
Serum (n=5)	95	91-99
Urine (n=5)	91	82-99

Linearity

To assess the linearity of the assay, samples spiked with or containing high concentrations of Pro-MMP-9 were diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.

Scientific Data Examples for Human MMP-9 Quantikine ELISA Kit

	Human MMP-9 ELISA Standard Curve

Preparation and Storage

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: MMP-9

Matrix metalloproteinases (MMPs), also called matrixins, constitute a family of zinc and calcium dependent endopeptidases that function in the breakdown of the extracellular matrix (ECM) and in the processing of a variety of molecules in different subcellular environments. They play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction, and tissue remodeling (1, 2). They also participate in inflammatory and autoimmune disorders such as arthritis, cancer, and cardiovascular disease (3-5). While the amounts of newly synthesized MMPs are regulated mainly at the levels of transcription, the proteolytic activities of existing MMPs are controlled through both the activation of proenzymes or zymogens and the inhibition of active enzymes by endogenous inhibitors, alpha 2-Macroglobulin, and tissue inhibitors of metalloproteinases (TIMPs) (6).

MMP-9 (also referred to as gelatinase B, 92 kDa type IV collagenase, 92 kDa gelatinase, and type V collagenase) is secreted as a glycosylated proenzyme (6-8). Activation of the proenzyme involves proteolytic removal of the N-terminal pro region, resulting in the 82 kDa active enzyme (9, 10). Active human MMP-9 shares 72% and 74% amino acid sequence identity with mouse and rat MMP-9, respectively. In addition to the zinc-binding site, the catalytic domain also contains three contiguous fibronectin type II homology units responsible for binding gelatin (11). A proline-rich hinge region links the catalytic domain to the C-terminal hemopexin-like domain. In vitro treatment of the proenzyme with 4-aminophenylmercuric acetate (APMA) produces not only the active enzyme but also a C-terminal truncated form with activity comparable to that of the active form (12). MMP-9 degrades components of the ECM with high specific activity for denatured collagens (gelatin). It can cleave native collagens of type III, IV, V, and XI, as well as Elastin, Nidogen-1, and Vitronectin (2, 3). MMP-9 can also cleave a variety of chemokines and growth factors (e.g. IL-1 beta, CXCL8/IL-8, CXCL7, CXCL4, CXCL1, Latent TGF-beta, membrane bound TNF-alpha, VEGF, and FGF basic), Amyloid beta peptide, Substance P, and Myelin Basic Protein (3, 13-15). This action can increase or decrease the biological activity of soluble factors and can also liberate them from association with the ECM (16, 17). MMP-9 can also trigger signaling through various transmembrane proteins or inhibit signaling by inducing their shedding from the cell surface (e.g. CD44, E-Cadherin, Integrins, ICAM-1, and IL-2 R alpha ) (3, 18-20).

MMP-9 is produced by a variety of normal and transformed cells including neutrophils, monocytes, macrophages, astrocytes, fibroblasts, osteoclasts, chondrocytes, keratinocytes, endothelial and epithelial cells. It exerts physiological and pathological angiogenic and remodeling effects on the vasculature (21-25). Activated neutrophils release proMMP-9 which is free of TIMP-1, allowing the liberation of pro-angiogenic FGF-2 from the ECM (17). MMP-9 in complex with TIMP-1 does not induce FGF-2 release (17). Neutrophil-derived MMP-9 exacerbates the inflammatory response, in part by generating collagen-derived peptides that induce the release of additional neutrophil MMP9 (26). MMP-9 also plays a role in bone formation and remodeling (1, 21, 27), methamphetamineinduced behavioral sensitization and reward (28), the regulation of neuronal synapse remodeling (29), trophoblast invasion during implantation (30), and the inactivation of Serpin alpha 1-Proteinase Inhibitor (31). The shedding of adhesion proteins by MMP-9 has a direct effect on tumor cell invasiveness (18-20).

Circulating levels of MMP-9 are increased in many inflammatory disorders including intraluminal thrombus formation (32), atherosclerosis (33), Crohn's disease (34), hepatitis C virus infection (35), colorectal cancer (36), and Duchenne muscular dystrophy (37). The ratio of MMP-9 to TIMP-1 is also increased in multiple sclerosis serum (38) and cystic fibrosis sputum (39), but it is decreased in the serum during cytomegalovirus infection (40). Levels of free MMP-9 and complexes of MMP-9 with Lipocalin-2/NGAL are elevated in the urine of ovarian cancer and uterine tract infection patients, respectively (41, 42).

Item	Value
Long Name	Matrix Metalloproteinase 9
Entrez Gene IDs	4318 (Human); 17395 (Mouse); 81687 (Rat); 102117693 (Cynomolgus Monkey)
Alternate Names	92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, EC 3.4.24, EC 3.4.24.35, GELB, Gelatinase B, MANDP2, MMP-9, MMP9, macrophage gelatinase, matrix metallopeptidase 9, matrix metalloproteinase 9, matrix metalloproteinase-9, type V collagenase

Citations for Human MMP-9 Quantikine ELISA Kit (208)

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Citations are publications that use Bio-Techne products. Selected citations for Human MMP-9 Quantikine ELISA Kit include:

Species: Human
Sample Types: Tissue Homogenates

J Kudelski et al. (2023-01-01), The Significance of Matrix Metalloproteinase 9 (MMP-9) and Metalloproteinase 2 (MMP-2) in Urinary Bladder Cancer Biomedicines, 11(3).
PMID: 36979935
Species: Human
Sample Types: Serum

C Xie et al. (2022-01-01), Increased serum LOXL2 concentration in pelvic inflammatory disease with pelvic adhesion Oncogene, 22(1):59.
PMID: 35246120
Species: Human
Sample Types: Serum

J Jarecki et al. (2022-01-01), Concentration of Selected Metalloproteinases and Osteocalcin in the Serum and Synovial Fluid of Obese Women with Advanced Knee Osteoarthritis International Journal of Environmental Research and Public Health, 19(6).
PMID: 35329213
Species: Human
Sample Types: Cell Culture Supernates

L Raimondi et al. (2022-01-01), Potential Anti-Metastatic Role of the Novel miR-CT3 in Tumor Angiogenesis and Osteosarcoma Invasion International Journal of Molecular Sciences, 23(2).
PMID: 35054891
Species: Human
Sample Types: Serum

M Dreiner et al. (2022-01-01), Relationship between different serum cartilage biomarkers in the acute response to running and jumping in healthy male individuals Scientific Reports, 12(1):6434.
PMID: 35440750
Species: Human
Sample Types: Plasma

C Jiguet-Jig et al. (2022-01-01), Plasmatic MMP9 released from tumor-infiltrating neutrophils is predictive for bevacizumab efficacy in glioblastoma patients: an AVAglio ancillary study Acta neuropathologica communications, 10(1):1.
PMID: 34980260
Species: Human
Sample Types: Cell Culture Supernates

BG Jung et al. (2022-01-01), Early IL-17A production helps establish Mycobacterium intracellulare infection in mice PloS Pathogens, 18(4):e1010454.
PMID: 35363832
Species: Human
Sample Types: Cell Culture Supernates

S Okikawa et al. (2022-01-01), Inhibition of the VEGF signaling pathway attenuates tumor?associated macrophage activity in liver cancer Oncology reports, 47(4).
PMID: 35169858
Species: Human
Sample Types: Tears

M de la Fuen et al. (2022-01-01), Elevation of Tear MMP-9 Concentration as a Biomarker of Inflammation in Ocular Pathology by Antibody Microarray Immunodetection Assays International Journal of Molecular Sciences, 23(10).
PMID: 35628448
Species: Human
Sample Types: Plasma

SA Maskarinec et al. (2022-01-01), Neutrophil functional heterogeneity is a fixed phenotype and is associated with distinct gene expression profiles Journal of leukocyte biology, 0(0).
PMID: 35916035
Species: Human
Sample Types: Cell Culture Supernates

Y Lu et al. (2022-01-01), A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma Nature Communications, 13(1):4594.
PMID: 35933472
Species: Cynomolgus Macaque
Sample Types: Tissue Homogenates

H Ma et al. (2022-01-01), Long-term persistence of viral RNA and inflammation in the CNS of macaques exposed to aerosolized Venezuelan equine encephalitis virus Oncogene, 18(6):e1009946.
PMID: 35696423
Species: Human
Sample Types: Serum

GJ Wang et al. (2022-01-01), Cluster of Differentiation 147 (CD147) serves as a promoter of atherosclerosis in patients with cerebral infarction European review for medical and pharmacological sciences, 26(16):5710-5717.
PMID: 36066144
Species: Human
Sample Types: Serum

L Zhu et al. (2022-01-01), microRNA-223 and microRNA-126 are clinical indicators for predicting the plaque stability in carotid atherosclerosis patients Journal of human hypertension, 0(0).
PMID: 36192429
Species: Human
Sample Types: Serum

A Bahabayi et al. (2022-01-01), Expression of Matrix Metalloproteinase-2,-7,-9 in Serum during Pregnancy in Patients with Pre-Eclampsia: A Prospective Study International Journal of Environmental Research and Public Health, 19(21).
PMID: 36361378
Species: Human
Sample Types: Serum

A Quesnel et al. (2022-01-01), The diagnostic and prognostic potential of the EGFR/MUC4/MMP9 axis in glioma patients Scientific Reports, 12(1):19868.
PMID: 36400876
Species: Human
Sample Types: Serum

I Tsomidis et al. (2022-01-01), Enzymes of Fibrosis in Chronic Liver Disease Biomedicines, 10(12).
PMID: 36551935
Species: Human
Sample Types: Serum

LY Wang et al. (2022-01-01), Factors Associated with RANTES, EMMPIRIN, MMP2 and MMP9, and the Association of These Biomarkers with Cardiovascular Disease in a Multi-Ethnic Population Journal of Clinical Medicine, 11(24).
PMID: 36555898
Species: Human
Sample Types: Tissue Lysate

LTH Nguyen et al. (2022-01-01), Anti-Psoriatic Effect of Rheum palmatum L. and Its Underlying Molecular Mechanisms International Journal of Molecular Sciences, 23(24).
PMID: 36555642
Species: Human
Sample Types: Serum

JV Moxon et al. (2022-01-01), Serum angiopoietin-1 concentration does not distinguish patients with ischaemic stroke from those presenting to hospital with ischaemic stroke mimics BMC cardiovascular disorders, 22(1):462.
PMID: 36333663
Species: Human
Sample Types: Whole Blood

M Jamka et al. (2021-01-01), Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training Journal of Clinical Medicine, 10(8).
PMID: 33921520
Species: Human
Sample Types: Serum

S Sriphoosan et al. (2021-01-01), Effect of vitamin D supplementation in patients with chronic hepatitis C after direct-acting antiviral treatment: a randomized, double-blind, placebo-controlled trial PeerJ, 9(0):e10709.
PMID: 33614272
Species: Human
Sample Types: Serum

C Guo et al. (2021-01-01), Serum sphingolipid profile in asthma Journal of leukocyte biology, 0(0).
PMID: 33600023
Species: Human
Sample Types: Serum

J Jarecki et al. (2021-01-01), Level of Adiponectin, Leptin and Selected Matrix Metalloproteinases in Female Overweight Patients with Primary Gonarthrosis Journal of Clinical Medicine, 10(6).
PMID: 33803785
Species: Primate
Sample Types: Plasma

JR Albe et al. (2021-01-01), Physiological and immunological changes in the brain associated with lethal eastern equine encephalitis virus in macaques PloS Pathogens, 17(2):e1009308.
PMID: 33534855
Species: Human
Sample Types: Plasma

L Scola et al. (2021-01-01), Polymorphisms of Pro-Inflammatory IL-6 and IL-1&beta Cytokines in Ascending Aortic Aneurysms as Genetic Modifiers and Predictive and Prognostic Biomarkers Biomolecules, 11(7).
PMID: 34202072
Species: Human
Sample Types: Cell Culture Supernates

X Li et al. (2021-01-01), High expression of Rab31 confers a poor prognosis and enhances cell proliferation and invasion in oral squamous cell carcinoma Oncology reports, 0(0).
PMID: 33469675
Species: Human
Sample Types: Serum

K Wadowska et al. (2021-01-01), New Insights on Old Biomarkers Involved in Tumor Microenvironment Changes and Their Diagnostic Relevance in Non-Small Cell Lung Carcinoma Biomolecules, 11(8).
PMID: 34439874
Species: Human
Sample Types: Cell Culture Supernates

A Kuzumi et al. (2021-01-01), Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis Nature Communications, 12(1):5947.
PMID: 34642338
Species: Human
Sample Types: Cell Culture Supernates

Y Wu et al. (2021-01-01), Cyclophilin A regulates secretion of tumour-derived extracellular vesicles Translational Oncology, 14(8):101112.
PMID: 33984826
Species: Human
Sample Types: Plasma

MM Ali et al. (2021-01-01), CD147 Levels in Blood and Adipose Tissues Correlate with Vascular Dysfunction in Obese Diabetic Adults Journal of cardiovascular development and disease, 9(1).
PMID: 35050217
Species: Human
Sample Types: Cell Culture Supernates

D Bakkalci et al. (2021-01-01), Bioengineering the ameloblastoma tumour to study its effect on bone nodule formation Scientific Reports, 11(1):24088.
PMID: 34916549
Species: Human
Sample Types: Plasma

S Nawrocka-M et al. (2021-01-01), Differences in the Biomarker Profile of De Novo Acute Heart Failure versus Decompensation of Chronic Heart Failure Biomolecules, 11(11).
PMID: 34827701
Species: Human
Sample Types: Cell Culture Supernates

F Kang et al. (2021-01-01), Controlled growth factor delivery system with osteogenic-angiogenic coupling effect for bone regeneration Journal of Orthopaedic Translation, 31(0):110-125.
PMID: 34976731
Species: Human
Sample Types: Saliva

YJ Shin et al. (2021-01-01), Diagnostic and prognostic ability of salivary MMP-9 for oral squamous cell carcinoma: A pre-/post-surgery case and matched control study PLoS ONE, 16(3):e0248167.
PMID: 33735248
Species: Human
Sample Types: Serum

M Yamauchi et al. (2020-01-01), Diagnostic performance of serum interferon gamma, matrix metalloproteinases, and periostin measurements for pulmonary tuberculosis in Japanese patients with pneumonia PLoS ONE, 15(1):e0227636.
PMID: 31917802
Species: Human
Sample Types: Cell Culture Supernates

YY Liu et al. (2020-01-01), Activity of fibroblast-like synoviocytes in rheumatoid arthritis was impaired by dickkopf-1 targeting siRNA Chin. Med. J., 0(6):679-686.
PMID: 32068606
Species: Human
Sample Types: Serum

S Hayat et al. (2020-01-01), Association of matrix metalloproteinase-9 polymorphism with severity of Guillain-Barrï¿½ syndrome J. Neurol. Sci., 415(0):116908.
PMID: 32447054
Species: Human
Sample Types: cell culture supernatant

J Jandova et al. (2020-01-01), Genetic Target Modulation Employing CRISPR/Cas9 Identifies Glyoxalase 1 as a Novel Molecular Determinant of Invasion and Metastasis in A375 Human Malignant Melanoma Cells In Vitro and In Vivo Cancers (Basel), 12(6).
PMID: 32466621
Species: Human
Sample Types: Serum

AE Stanciu et al. (2020-01-01), Serum melatonin is inversely associated with matrix metalloproteinase-9 in oral squamous cell carcinoma Oncol Lett, 19(4):3011-3020.
PMID: 32218858
Species: Human
Sample Types: Plasma

CS Kuo et al. (2020-01-01), Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance Sci Rep, 10(1):1725.
PMID: 32015418
Species: Human
Sample Types: Urine

VG Arcos-Sacr et al. (2020-01-01), Urinary MMP-9/UCr association with albumin concentration and albumin-creatinine-ratio in Mexican patients with type 2 diabetes mellitus PeerJ, 8(0):e10474.
PMID: 33362965
Species: Human
Sample Types: Serum

A Waszczykow et al. (2020-01-01), Matrix Metalloproteinases MMP-2 and MMP-9, Their Inhibitors TIMP-1 and TIMP-2, Vascular Endothelial Growth Factor and sVEGFR-2 as Predictive Markers of Ischemic Retinopathy in Patients with Systemic Sclerosis-Case Series Report Int J Mol Sci, 21(22).
PMID: 33218057
Species: Human
Sample Types: Cell Culture Supernates

JJ Noh et al. (2020-01-01), Anti-Cancer Activity of As4O6 and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer Pharmaceutics, 12(10).
PMID: 33086573
Species: Human
Sample Types: Serum

MMS Balla et al. (2020-01-01), Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients Transl Oncol, 14(1):100933.
PMID: 33188981
Species: Human
Sample Types: Cell Culture Supernates

T Phillips et al. (2020-01-01), Aberrant recruitment of leukocytes defines poor wound healing in patients with recessive dystrophic epidermolysis bullosa J Dermatol Sci, 0(0).
PMID: 33143962
Species: Human
Sample Types: Cell Culture Supernates

J Jandova et al. (2020-01-01), Genomic GLO1 deletion modulates TXNIP expression, glucose metabolism, and redox homeostasis while accelerating human A375 malignant melanoma tumor growth Redox Biology, 39(0):101838.
PMID: 33360689
Species: Human
Sample Types: Serum

H Kook et al. (2020-01-01), Identification of plaque ruptures using a novel discriminative model comprising biomarkers in patients with acute coronary syndrome Sci Rep, 10(1):20228.
PMID: 33214686
Species: Human
Sample Types: Cell Culture Supernates, Whole Cells

L Raimondi et al. (2020-01-01), Multiple Myeloma-Derived Extracellular Vesicles Induce Osteoclastogenesis through the Activation of the XBP1/IRE1alpha Axis Cancers (Basel), 12(8).
PMID: 32759820
Species: Human
Sample Types: Serum

A Darlix et al. (2019-01-01), The prognostic value of theï¿½Tau protein serum level in metastatic breast cancer patients and its correlation with brain metastases BMC Cancer, 19(1):110.
PMID: 30700265
Species: Human
Sample Types: Serum

L Lorente et al. (2019-01-01), Persistently high circulating tissue inhibitor of matrix metalloproteinase-1 levels in non-survivor brain trauma injury patients J Crit Care, 51(0):117-121.
PMID: 30802757
Species: Human
Sample Types: Plasma

M Matulka et al. (2019-01-01), Expression and Concentration of Matrix Metalloproteinase 9 and Tissue Inhibitor of Matrix Metalloproteinases 1 in Laryngeal Squamous Cell Carcinoma Dis. Markers, 2019(0):3136792.
PMID: 31143300
Species: Human
Sample Types: Cell Culture Supernates

N Sabbah et al. (2019-01-01), Small size apolipoprotein(a) isoforms enhance inflammatory and proteolytic potential of collagen-primed monocytes Lipids Health Dis, 18(1):166.
PMID: 31470857
Species: Human
Sample Types: Serum

L Lorente et al. (2019-01-01), High serum levels of tissue inhibitor of matrix metalloproteinase-1 during the first week of a malignant middle cerebral artery infarction in non-surviving patients BMC Neurol, 19(1):167.
PMID: 31319804
Species: Human
Sample Types: Plasma

B Singh et al. (2019-01-01), Effect of doxycyline in chronic obstructive pulmonary disease - An exploratory study Pulm Pharmacol Ther, 0(0):101831.
PMID: 31349003
Species: Human
Sample Types: Plasma

DP Zhang et al. (2019-01-01), Basilar Artery Tortuosity Is Associated With White Matter Hyperintensities by TIMP-1 Front Neurosci, 13(0):836.
PMID: 31474817
Species: Human
Sample Types: Saliva

A Kobus et al. (2019-01-01), Levels of Selected Matrix Metalloproteinases, Their Inhibitors in Saliva, and Oral Status in Juvenile Idiopathic Arthritis Patients vs. Healthy Controls Biomed Res Int, 2019(0):7420345.
PMID: 31781639
Species: Human
Sample Types: Plasma

HL Lung et al. (2019-01-01), Serum amyloid A1 polymorphisms as risk factors in oesophageal squamous cell carcinoma Hong Kong Med J, 25(5):4-8.
PMID: 31761762
Species: Human
Sample Types: Plasma

Z Wang et al. (2019-01-01), ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease Dis. Markers, 2019(0):6129748.
PMID: 31929842
Species: Human
Sample Types: Serum

D Štrbac et al. (2019-01-01), Evaluation of Matrix Metalloproteinase 9 Serum Concentration as a Biomarker in Malignant Mesothelioma Dis. Markers, 2019(0):1242964.
PMID: 31191742
Species: Human
Sample Types: Serum

O Dörr et al. (2018-01-01), Specific biomarkers of myocardial inflammation and remodeling processes as predictors of mortality in high-risk patients undergoing percutaneous mitral valve repair (MitraClip) Clin Cardiol, 0(0).
PMID: 29663512
Species: Human
Sample Types: Cell Culture Supernates

J Ma et al. (2018-01-01), miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development J. Exp. Clin. Cancer Res., 37(1):19.
PMID: 29391048
Species: Human
Sample Types: Serum

M Sakuma et al. (2018-01-01), Mobilization of progenitor cells and assessment of vessel healing after second generation drug-eluting stenting by optical coherence tomography Int J Cardiol Heart Vasc, 18(0):17-24.
PMID: 29556525
Species: Human
Sample Types: Tissue Homogenates

A Bálint et al. (2018-01-01), How disease extent can be included in the endoscopic activity index of ulcerative colitis: the panMayo score, a promising scoring system BMC Gastroenterol, 18(1):7.
PMID: 29310593
Species: Human
Sample Types: Serum

AE Stanciu et al. (2018-01-01), The role of pro-fibrotic biomarkers in paroxysmal and persistent atrial fibrillation Cytokine, 103(0):63-68.
PMID: 29324263
Species: Human
Sample Types: Serum

CD Ruediger et al. (2018-01-01), Influence of ethnic background on left atrial markers of inflammation, endothelial function and tissue remodelling Indian Pacing Electrophysiol J, 18(1):1-5.
PMID: 29477215
Species: Human
Sample Types: Plasma

M Zajkowska et al. (2018-01-01), Diagnostic power of VEGF, MMP-9 and TIMP-1 in patients with breast cancer. A multivariate statistical analysis with ROC curve Adv Med Sci, 64(1):1-8.
PMID: 30227310
Species: Human
Sample Types: Serum

Y Li et al. (2018-01-01), Association of Polymorphisms of the Matrix Metalloproteinase 9 Gene with Ischaemic Stroke in a Southern Chinese Population Cell. Physiol. Biochem., 49(6):2188-2199.
PMID: 30257242
Species: Human
Sample Types: Cell Culture Supernates

S Zeng et al. (2018-01-01), Zeylenone represses the progress of human prostate cancer by downregulating the Wnt/??catenin pathway Mol Med Rep, 0(0).
PMID: 30365080
Species: Human
Sample Types: Urine

DC Woodworth et al. (2018-01-01), Changes in brain white matter structure are associated with urine proteins in urologic chronic pelvic pain syndrome (UCPPS): A MAPP Network study PLoS ONE, 13(12):e0206807.
PMID: 30517112
Species: Human
Sample Types: Plasma

H Yogasundar et al. (2018-01-01), Elevated Inflammatory Plasma Biomarkers in Patients With Fabry Disease: A Critical Link to Heart Failure With Preserved Ejection Fraction J Am Heart Assoc, 7(21):e009098.
PMID: 30571380
Species: Human
Sample Types: Plasma

CK Wu et al. (2018-01-01), Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients J Clin Med, 7(11).
PMID: 30413105
Species: Human
Sample Types: Cell Culture Supernates

ZJ Shen et al. (2018-01-01), Telmisartan inhibits Ang II-induced MMP-9 expression in macrophages in stabilizing atheromatous plaque Eur Rev Med Pharmacol Sci, 22(22):8004-8012.
PMID: 30536349
Species: Human
Sample Types: Urine

AU García-Tej et al. (2018-01-01), Association of urinary activity of MMP-9 with renal impairment in Mexican patients with type 2 diabetes mellitus PeerJ, 6(0):e6067.
PMID: 30564523
Species: Human
Sample Types: Plasma
Applications: ELISA Capture

CN Ajaero et al. (2018-01-01), Does cardiac resynchronization therapy restore peripheral circulatory homeostasis? ESC Heart Fail, 5(1):129-138.
PMID: 29030923
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Capture

A Aldhahrani et al. (2018-01-01), The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis Laryngoscope, 0(0).
PMID: 29399801
Species: Human
Sample Types: Serum
Applications: ELISA Capture

W Szcz?sny et al. (2018-01-01), Activity of metalloproteinases and adiponectin in obese patients-a possible factor of incisional hernias after bariatric procedures J Zhejiang Univ Sci B, 19(1):65-70.
PMID: 29308609
Species: Human
Sample Types: Plasma

C Robinson et al. (2018-01-01), Nesfatin-1 and visfatin expression is associated with reduced atherosclerotic disease risk in patients with rheumatoid arthritis Peptides, 102(0):31-37.
PMID: 29475075
Species: Human
Sample Types: Serum

VK Snowdon et al. (2017-01-01), Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial PLoS Med, 14(2):e1002248.
PMID: 28245243
Species: Human
Sample Types: Cell Culture Supernates

F Reggiani et al. (2017-01-01), Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression Cancer Res., 0(0).
PMID: 28754674
Species: Human
Sample Types: Tissue Culture Supernates

M Lombardi et al. (2017-01-01), P2X7 receptor antagonism modulates IL-1? and MMP9 in human atherosclerotic vessels Sci Rep, 7(1):4872.
PMID: 28687781
Species: Human
Sample Types: Urine

T Shimura et al. (2017-01-01), Urinary kallikrein 10 predicts the incurability of gastric cancer Oncotarget, 8(17):29247-29257.
PMID: 28418926
Species: Human
Sample Types: Serum

M Skerenova et al. (2017-01-01), Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 0(0).
PMID: 28529342
Species: Human
Sample Types: Serum

LG Gardinassi et al. (2017-01-01), Molecular signatures of neutrophil extracellular traps in human visceral leishmaniasis Parasit Vectors, 10(1):285.
PMID: 28583201
Species: Human
Sample Types: CSF

S Mailankody et al. (2017-01-01), Cerebrospinal fluid matrix metalloproteinase 9 levels, blood-brain barrier permeability, and treatment outcome in tuberculous meningitis PLoS ONE, 12(7):e0181262.
PMID: 28704492
Species: Human
Sample Types: Plasma

J Zhuang et al. (2017-01-01), Comparison of circulating dendritic cell and monocyte subsets at different stages of atherosclerosis: insights from optical coherence tomography BMC Cardiovasc Disord, 17(1):270.
PMID: 29047360
Species: Human
Sample Types: Plasma

Y Ozaki et al. (2017-01-01), Association of Toll-Like Receptor 4 on Human Monocyte Subsets and Vulnerability Characteristics of Coronary Plaque as Assessed by 64-Slice Multidetector Computed Tomography Circ. J, 0(0).
PMID: 28344199
Species: Human
Sample Types: Serum

C Ciavarella et al. (2017-01-01), The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm Stem Cell Res Ther, 8(1):99.
PMID: 28446225
Species: Human
Sample Types: Serum

ME Niño et al. (2017-01-01), TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model PLoS ONE, 12(2):e0171191.
PMID: 28192449
Species: Human
Sample Types: Serum

M Lipczy?ska et al. (2017-01-01), Collagen turnover biomarkers and systemic right ventricle remodeling in adults with previous atrial switch procedure for transposition of the great arteries PLoS ONE, 12(8):e0180629.
PMID: 28767656
Species: Human
Sample Types: Cell Culture Supernates

E Aberdam et al. (2017-01-01), Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing PLoS ONE, 12(6):e0179913.
PMID: 28640863
Species: Human
Sample Types: Plasma

SR Langley et al. (2017-01-01), Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques J. Clin. Invest, 0(0).
PMID: 28319050
Species: Human
Sample Types: Serum

R Mechmeche et al. (2017-01-01), Late mitral restenosis after percutaneous commissurotomy: Predictive value of inflammation and extracellular matrix remodeling biomarkers Heart Lung, 0(0).
PMID: 28450150
Species: Human
Sample Types: Serum

J Matsumoto et al. (2017-01-01), Altered serum level of matrix metalloproteinase-9 and its association with decision-making in eating disorders Psychiatry Clin. Neurosci., 71(2):124-134.
PMID: 27891714
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), The C-terminus of IGFBP-5 suppresses tumor growth by inhibiting angiogenesis Sci Rep, 6(0):39334.
PMID: 28008951
Species: Human
Sample Types: Urine

Shimizu Y et al. (2016-01-01), A multiplex immunoassay for the non-invasive detection of bladder cancer. J Transl Med, 14(1):31.
PMID: 26830497
Species: Human
Sample Types: Serum

(2016-01-01), Differential diagnosis of lung cancer, its metastasis and chronic obstructive pulmonary disease based on serum Vegf, Il-8 and MMP-9 Sci Rep, 6(0):36065.
PMID: 27811960
Species: Human
Sample Types: Amniotic Fluid

(2016-01-01), Data on clinical significance of second trimester inflammatory biomarkers in the amniotic fluid in predicting preterm delivery Data Brief, 9(0):47-50.
PMID: 27626053
Species: Human
Sample Types: Serum

Iwona Kurkowska- (2016-01-01), Serum metalloproteinase 9 levels increase after generalized tonic-clonic seizures Epilepsy Res., 129(0):33-36.
PMID: 27886560
Species: Human
Sample Types: Cell Culture Supernates

Teng Y et al. (2015-01-01), Targeting the WASF3-CYFIP1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion. Cancer Res, 76(4):965-73.
PMID: 26676744
Species: Human
Sample Types: Cell Culture Supernates

Kmiecik A et al. (2015-01-01), Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression. PLoS ONE, 10(5):e0124865.
PMID: 25933064
Species: Human
Sample Types: BALF

Li L et al. (2014-01-01), Icariin ameliorates cigarette smoke induced inflammatory responses via suppression of NF-kappaB and modulation of GR in vivo and in vitro. PLoS ONE, 9(8):e102345.
PMID: 25089961
Species: Human
Sample Types: Cell Culture Supernates

Giuliani M et al. (2014-01-01), TLR ligands stimulation protects MSC from NK killing. Stem Cells, 32(1):290-300.
PMID: 24123639
Species: Human
Sample Types: Cell Culture Supernates

Naik et al. (2014-01-01), Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe? BMC Neurosci, 15(0):51.
PMID: 24755281
Species: Human
Sample Types: Serum

Braicu E et al. (2014-01-01), Role of serum VEGFA, TIMP2, MMP2 and MMP9 in monitoring response to adjuvant radiochemotherapy in patients with primary cervical cancer--results of a companion protocol of the randomized NOGGO-AGO phase III clinical trial. Anticancer Res, 34(1):385-91.
PMID: 24403492
Species: Human
Sample Types: Cell Culture Supernates

Yang M et al. (2014-01-01), KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-kappaB and VEGF-C. Anticancer Res, 34(7):3469-74.
PMID: 24982355
Species: Human
Sample Types: Cell Culture Supernates

Steinestel K et al. (2014-01-01), Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells. Mol Cancer, 13(0):145.
PMID: 24913355
Species: Human
Sample Types: Cell Culture Supernates

Chana K et al. (2014-01-01), Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol, 133(1):207-16.e1-11.
PMID: 24176116
Species: Human
Sample Types: Urine

Rosser et al. (2014-01-01), Simultaneous multi-analyte urinary protein assay for bladder cancer detection. BMC Biotechnol, 14(0):24.
PMID: 24684904
Species: Human
Sample Types: Cell Culture Supernates

Lee H et al. (2014-01-01), Epigalloccatechin-3-gallate inhibits ocular neovascularization and vascular permeability in human retinal pigment epithelial and human retinal microvascular endothelial cells via suppression of MMP-9 and VEGF activation. Molecules, 19(8):12150-72.
PMID: 25123184
Species: Human
Sample Types: Urine

Li S et al. (2014-01-01), Matrix metalloproteinase-9 deficiency attenuates diabetic nephropathy by modulation of podocyte functions and dedifferentiation. Kidney Int, 86(2):358-69.
PMID: 24670409
Species: Human
Sample Types: Serum

Lorente L et al. (2014-01-01), Association between serum tissue inhibitor of matrix metalloproteinase-1 levels and mortality in patients with severe brain trauma injury. PLoS ONE, 9(4):e94370.
PMID: 24728097
Species: Human
Sample Types: Urine

El-Sharkawi et al. (2014-01-01), The biochemical value of urinary metalloproteinases 3 and 9 in diagnosis and prognosis of bladder cancer in Egypt. J Biomed Sci, 21(0):72.
PMID: 25135219
Species: Human
Sample Types: Serum

Braicu E et al. (2013-01-01), Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy. Cytokine, 61(3):755-8.
PMID: 23415672
Species: Human
Sample Types: Plasma

Malaponte G et al. (2013-01-01), IL-6-174 G > C and MMP-9-1562 C > T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients. Cytokine, 62(1):64-9.
PMID: 23490413
Species: Human
Sample Types: Cell Culture Supernates

Liu X et al. (2013-01-01), Antiproliferative, antiinvasive, and proapoptotic activity of folate receptor alpha-targeted liposomal doxorubicin in nonfunctional pituitary adenoma cells. Endocrinology, 154(4):1414-23.
PMID: 23462961
Species: Human
Sample Types: Cell Culture Supernates

Kaimal R et al. (2013-01-01), Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer. Cancer Res, 73(8):2457-67.
PMID: 23423981
Species: Human
Sample Types: Urine

Goodison et al. (2012-01-01), A multi-analyte assay for the non-invasive detection of bladder cancer. PLoS ONE, 7(10):e47469.
PMID: 23094052
Species: Human
Sample Types: Saliva

Jaedicke KM et al. (2012-01-01), Validation and quality control of ELISAs for the use with human saliva samples. J. Immunol. Methods, 377(1):62-5.
PMID: 22306358
Species: Human
Sample Types: CSF

Tiberti N et al. (2012-01-01), Cerebrospinal Fluid Neopterin as Marker of the Meningo-Encephalitic Stage of Trypanosoma brucei gambiense Sleeping Sickness. PLoS ONE, 7(7):e40909.
PMID: 22815865
Species: Human
Sample Types: Serum

Jonasson S et al. (2011-01-01), Increased levels of leukocyte-derived MMP-9 in patients with stable angina pectoris. PLoS ONE, 6(4):e19340.
PMID: 21559401
Species: Human
Sample Types: Saliva

Wood LG et al. (2011-01-01), Characterization of innate immune signalling receptors in virus-induced acute asthma. Clin. Exp. Allergy, 41(5):640-8.
PMID: 21129050
Species: Human
Sample Types: Serum

Aronis KN et al. (2011-01-01), Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans. Diabetologia, 54(9):2358-67.
PMID: 21660636
Species: Human
Sample Types: Serum

Hansson J et al. (2011-01-01), Biomarkers of extracellular matrix metabolism (MMP-9 and TIMP-1) and risk of stroke, myocardial infarction, and cause-specific mortality: cohort study. PLoS ONE, 6(1):e16185.
PMID: 21283828
Species: Human
Sample Types: Serum

Hanefeld M et al. (2011-01-01), Double-blind, randomized, multicentre, and active comparator controlled investigation of the effect of Pioglitazone, Metformin, and the combination of both on cardiovascular risk in patients with type 2 diabetes receiving stable basal insulin therapy: the PIOCOMB study. Cardiovasc Diabetol, 10(0):65.
PMID: 21756323
Species: Human
Sample Types: Cell Culture Supernates

Verma S et al. (2011-01-01), Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes. J. Gen. Virol., 92(0):507-15.
PMID: 21106803
Species: Human
Sample Types: Serum

Mroczko B et al. (2010-01-01), The diagnostic value of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of matrix metalloproteinases 1 (TIMP-1) determination in the sera of colorectal adenoma and cancer patients. Int J Colorectal Dis, 25(10):1177-84.
PMID: 20556397
Species: Human
Sample Types: Sputum

Katial RK et al. (2010-01-01), The effect of aspirin desensitization on novel biomarkers in aspirin-exacerbated respiratory diseases. J. Allergy Clin. Immunol., 126(4):738-44.
PMID: 20728206
Species: Human
Sample Types: Saliva

Wood LG et al. (2010-01-01), Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma. Clin. Exp. Allergy, 40(2):232-41.
PMID: 19878195
Species: Human
Sample Types: Serum

Yeh YC et al. (2010-01-01), Elevated serum matrix metalloproteinase-3 and -7 in H. pylori-related gastric cancer can be biomarkers correlating with a poor survival. Dig. Dis. Sci., 55(6):1649-57.
PMID: 19690958
Species: Human
Sample Types: Cell Culture Supernates

Liu ZB et al. (2010-01-01), Inhibition of EGFR pathway signaling and the metastatic potential of breast cancer cells by PA-MSHA mediated by type 1 fimbriae via a mannose-dependent manner. Oncogene, 29(20):2996-3009.
PMID: 20228837
Species: Human
Sample Types: Cell Culture Supernates

Reikvam H et al. (2010-01-01), Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation. Eur. J. Haematol., 84(3):239-51.
PMID: 19922462
Species: Human
Sample Types: Plasma

Sesso R et al. (2010-01-01), Abnormalities in metalloproteinase pathways and IGF-I axis: a link between birth weight, hypertension, and vascular damage in childhood. Am. J. Hypertens., 23(1):6-11.
PMID: 19893495
Species: Human
Sample Types: Serum

Ghanim H et al. (2010-01-01), Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression. Am. J. Clin. Nutr., 91(4):940-9.
PMID: 20200256
Species: Human
Sample Types: Plasma

Buralli S et al. (2010-01-01), Circulating matrix metalloproteinase-3 and metalloproteinase-9 and tissue Doppler measures of diastolic dysfunction to risk stratify patients with systolic heart failure. Am. J. Cardiol., 105(6):853-6.
PMID: 20211331
Species: Human
Sample Types: Serum

Teles RM et al. (2010-01-01), High matrix metalloproteinase production correlates with immune activation and leukocyte migration in leprosy reactional lesions. Infect. Immun., 78(3):1012-21.
PMID: 20008541
Species: Human
Sample Types: CSF

Sanpool O et al. (2010-01-01), Cerebrospinal fluid u-plasminogen activator and matrix metalloproteinase-9 levels in human eosinophilic meningitis associated with angiostrongyliasis. Cytokine, 51(3):294-7.
PMID: 20584616
Species: Human
Sample Types: Cell Culture Supernates

Schneider P et al. (2010-01-01), In vitro secretion of matrix metalloprotease 9 is a prognostic marker in childhood acute lymphoblastic leukemia. Leuk. Res., 34(1):24-31.
PMID: 19748669
Species: Human
Sample Types: Plasma

Kawut SM et al. (2010-01-01), Matrix metalloproteinase-9 and plasminogen activator inhibitor-1 are associated with right ventricular structure and function: the MESA-RV Study. Biomarkers, 15(8):731-8.
PMID: 20923324
Species: Human
Sample Types: Plasma

Idriss NK et al. (2010-01-01), Plasma haemoxygenase-1 in coronary artery disease. A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor. Thromb. Haemost., 104(5):1029-37.
PMID: 20838751
Species: Human
Sample Types: Cell Culture Supernates

Krishnatry AS et al. (2010-01-01), Broad regulation of matrix and adhesion molecules in THP-1 human macrophages by nitroglycerin. Nitric Oxide, 22(1):11-7.
PMID: 19836459
Species: Human
Sample Types: Serum

Lorente L et al. (2009-01-01), Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis. Crit Care, 13(5):R158.
PMID: 19799791
Species: Human
Sample Types: Cell Culture Supernates

Amiable N et al. (2009-01-01), Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone, 44(6):1143-50.
PMID: 19264156
Species: Human
Sample Types: Serum

Roderfeld M et al. (2009-01-01), Serum matrix metalloproteinases in adult CF patients: Relation to pulmonary exacerbation. J. Cyst. Fibros., 8(5):338-47.
PMID: 19604728
Species: Human
Sample Types: Plasma

Rodriguez PC et al. (2009-01-01), Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res., 69(4):1553-60.
PMID: 19201693
Species: Human
Sample Types: Plasma

Hanusch-Enserer U et al. (2009-01-01), Non-conventional markers of atherosclerosis before and after gastric banding surgery. Eur. Heart J., 30(12):1516-24.
PMID: 19380349
Species: Human
Sample Types: Urine

Soler-Garcia AA et al. (2009-01-01), A urinary biomarker profile for children with HIV-associated renal diseases. Kidney Int., 76(2):207-14.
PMID: 19357719
Species: Human
Sample Types: Plasma

Wang PH et al. (2009-01-01), Significant elevation of plasma matrix metalloproteinase-9 level and its ratio to matrix metalloproteinase-2 in patients with pelvic inflammatory disease. Fertil. Steril., 92(5):1679-84.
PMID: 18937938
Species: Human
Sample Types: Plasma

Plat J et al. (2009-01-01), A plant stanol yogurt drink alone or combined with a low-dose statin lowers serum triacylglycerol and non-HDL cholesterol in metabolic syndrome patients. J. Nutr., 139(6):1143-9.
PMID: 19403719
Species: Human
Sample Types: Serum

Karapanagiotidis GT et al. (2009-01-01), Serum levels of matrix metalloproteinases -1,-2,-3 and -9 in thoracic aortic diseases and acute myocardial ischemia. J Cardiothorac Surg, 4(0):59.
PMID: 19886986
Species: Human
Sample Types: Cell Culture Supernates

Page K et al. (2009-01-01), A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice. J. Immunol., 183(5):3400-8.
PMID: 19667087
Species: Human
Sample Types: Serum

Glass-Marmor L et al. (2009-01-01), Immunomodulation by chronobiologically-based glucocorticoids treatment for multiple sclerosis relapses. J. Neuroimmunol., 210(1):124-7.
PMID: 19329193
Species: Human
Sample Types: Serum

Samnegard A et al. (2009-01-01), Gender specific associations between matrix metalloproteinases and inflammatory markers in post myocardial infarction patients. Atherosclerosis, 202(2):550-6.
PMID: 18619594
Species: Mouse
Sample Types: Cell Lysates

Feng W et al. (2008-01-01), The angiogenic response is dictated by beta3 integrin on bone marrow-derived cells. J. Cell Biol., 183(6):1145-57.
PMID: 19075116
Species: Human
Sample Types: Plasma

Castellano G et al. (2008-01-01), Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression. Clin. Cancer Res., 14(22):7470-80.
PMID: 19010864
Species: Human
Sample Types: Urine

Smith ER et al. (2008-01-01), Urinary biomarkers predict brain tumor presence and response to therapy. Clin. Cancer Res., 14(8):2378-86.
PMID: 18413828
Species: Human
Sample Types: Ascites Fluid

Cowden Dahl KD et al. (2008-01-01), Matrix metalloproteinase 9 is a mediator of epidermal growth factor-dependent e-cadherin loss in ovarian carcinoma cells. Cancer Res., 68(12):4606-13.
PMID: 18559505
Species: Human
Sample Types: BALF

Glader P et al. (2008-01-01), Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space. Eur. Respir. J., 32(3):644-50.
PMID: 18417512
Species: Human
Sample Types: Ovarian Ascites Fluid

Agarwal A et al. (2008-01-01), Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer. Mol. Cancer Ther., 7(9):2746-57.
PMID: 18790755
Species: Human
Sample Types: Tissue Homogenates

Bendrik C et al. (2008-01-01), Gene transfer of matrix metalloproteinase-9 induces tumor regression of breast cancer in vivo. Cancer Res., 68(9):3405-12.
PMID: 18451168
Species: Human
Sample Types: Vitreous Humor

Coral K et al. (2008-01-01), Lysyl oxidase activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachment. Invest. Ophthalmol. Vis. Sci., 49(11):4746-52.
PMID: 18566459
Species: Human
Sample Types: Sputum

Simpson JL et al. (2007-01-01), Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am. J. Respir. Crit. Care Med., 177(2):148-55.
PMID: 17947611
Species: Human
Sample Types: Cell Culture Supernates

Nabata A et al. (2007-01-01), C-reactive protein induces endothelial cell apoptosis and matrix metalloproteinase-9 production in human mononuclear cells: Implications for the destabilization of atherosclerotic plaque. Atherosclerosis, 196(1):129-35.
PMID: 17531242
Species: Human
Sample Types: Bone Marrow Fluid

Kissel CK et al. (2007-01-01), Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure. J. Am. Coll. Cardiol., 49(24):2341-9.
PMID: 17572250
Species: Human
Sample Types: Cell Culture Supernates

Bodet C et al. (2007-01-01), Actinobacillus actinomycetemcomitans lipopolysaccharide regulates matrix metalloproteinase, tissue inhibitors of matrix metalloproteinase, and plasminogen activator production by human gingival fibroblasts: a potential role in connective tissue destruction. J. Cell. Physiol., 212(1):189-94.
PMID: 17299802
Species: Human
Sample Types: Cell Culture Supernates

Vishnubhotla R et al. (2007-01-01), ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging. Lab. Invest., 87(11):1149-58.
PMID: 17876296
Species: Human
Sample Types: Cell Culture Supernates

Ma DH et al. (2007-01-01), Generation of endostatin by matrix metalloproteinase and cathepsin from human limbocorneal epithelial cells cultivated on amniotic membrane. Invest. Ophthalmol. Vis. Sci., 48(2):644-51.
PMID: 17251461
Species: Human
Sample Types: BALF

Huh JW et al. (2007-01-01), Is metalloproteinase-7 specific for idiopathic pulmonary fibrosis? Chest, 133(5):1101-6.
PMID: 18071010
Species: Human
Sample Types: Plasma

Wu CY et al. (2007-01-01), Plasma matrix metalloproteinase-9 level is better than serum matrix metalloproteinase-9 level to predict gastric cancer evolution. Clin. Cancer Res., 13(7):2054-60.
PMID: 17404086
Species: Human
Sample Types: Plasma

Kleinman ME et al. (2007-01-01), Hypoxia-induced mediators of stem/progenitor cell trafficking are increased in children with hemangioma. Arterioscler. Thromb. Vasc. Biol., 27(12):2664-70.
PMID: 17872454
Species: Human
Sample Types: BALF

Goleva E et al. (2007-01-01), Airway remodeling and lack of bronchodilator response in steroid-resistant asthma. J. Allergy Clin. Immunol., 120(5):1065-72.
PMID: 17900681
Species: Human
Sample Types: Sputum

Gaggar A et al. (2007-01-01), Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients. Am. J. Physiol. Lung Cell Mol. Physiol., 293(1):L96-L104.
PMID: 17384080
Species: Human
Sample Types: Plasma

Forst T et al. (2007-01-01), Pleiotrophic and anti-inflammatory effects of pioglitazone precede the metabolic activity in type 2 diabetic patients with coronary artery disease. Atherosclerosis, 197(1):311-7.
PMID: 17588584
Species: Human
Sample Types: Plasma

Zinner RG et al. (2007-01-01), Phase I clinical and pharmacodynamic evaluation of oral CI-1033 in patients with refractory cancer. Clin. Cancer Res., 13(10):3006-14.
PMID: 17505003
Species: Human
Sample Types: Serum

Yee LD et al. (2007-01-01), Pilot study of rosiglitazone therapy in women with breast cancer: effects of short-term therapy on tumor tissue and serum markers. Clin. Cancer Res., 13(1):246-52.
PMID: 17200362
Species: Human
Sample Types: Plasma

Apple FS et al. (2007-01-01), Multiple biomarker use for detection of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome. Clin. Chem., 53(5):874-81.
PMID: 17384009
Species: Human
Sample Types: Urine

Han WK et al. (2007-01-01), Urinary biomarkers in the early diagnosis of acute kidney injury. Kidney Int., 73(7):863-9.
PMID: 18059454
Species: Human
Sample Types: Tissue Homogenates

Zhao Z et al. (2007-01-01), Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro. Biochem. Biophys. Res. Commun., 358(2):528-33.
PMID: 17485071
Species: Human
Sample Types: Cell Culture Supernates

Borrelli V et al. (2006-01-01), Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions. Surgery, 140(3):454-63.
PMID: 16934609
Species: Human
Sample Types: Plasma

Sherman JA et al. (2006-01-01), Humoral and cellular factors responsible for coronary collateral formation. Am. J. Cardiol., 98(9):1194-7.
PMID: 17056326
Species: Human
Sample Types: Sputum

Adelroth E et al. (2006-01-01), Airway inflammation in iron ore miners exposed to dust and diesel exhaust. Eur. Respir. J., 27(4):714-9.
PMID: 16455836
Species: Human
Sample Types: Serum

Chu CS et al. (2006-01-01), Effects of rosiglitazone alone and in combination with atorvastatin on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Am. J. Cardiol., 97(5):646-50.
PMID: 16490430
Species: Human
Sample Types: Gingival Crevicular Fluid (GCF)

Johannsen A et al. (2006-01-01), Dental plaque, gingival inflammation, and elevated levels of interleukin-6 and cortisol in gingival crevicular fluid from women with stress-related depression and exhaustion. J. Periodontol., 77(8):1403-9.
PMID: 16937592
Species: Human
Sample Types: Cell Culture Supernates

Rofstad EK et al. (2006-01-01), Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res., 66(13):6699-707.
PMID: 16818644
Species: Human
Sample Types: Serum

Molica S et al. (2006-01-01), Serum levels of syndecan-1 in B-cell chronic lymphocytic leukemia: correlation with the extent of angiogenesis and disease-progression risk in early disease. Leuk. Lymphoma, 47(6):1034-40.
PMID: 16840194
Species: Human
Sample Types: BALF

Lee KS et al. (2006-01-01), Vascular endothelial growth factor modulates matrix metalloproteinase-9 expression in asthma. Am. J. Respir. Crit. Care Med., 174(2):161-70.
PMID: 16645174
Species: Human
Sample Types: Cell Culture Supernates

Merck E et al. (2006-01-01), Ligation of the FcR gamma chain-associated human osteoclast-associated receptor enhances the proinflammatory responses of human monocytes and neutrophils. J. Immunol., 176(5):3149-56.
PMID: 16493074
Species: Human
Sample Types: Gingival Crevicular Fluid (GCF)

Figueredo CM et al. (2005-01-01), Aberrant neutrophil reactions in periodontitis. J. Periodontol., 76(6):951-5.
PMID: 15948690
Species: Human
Sample Types: Sputum

Sagel SD et al. (2005-01-01), Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis. Pediatr. Pulmonol., 39(3):224-32.
PMID: 15635615
Species: Human
Sample Types: Nasal Fluid

Watelet JB et al. (2005-01-01), Neutrophil-derived metalloproteinase-9 predicts healing quality after sinus surgery. Laryngoscope, 115(1):56-61.
PMID: 15630367
Species: Human
Sample Types: Serum

Ko FW et al. (2005-01-01), A comparison of airway and serum matrix metalloproteinase-9 activity among normal subjects, asthmatic patients, and patients with asthmatic mucus hypersecretion. Chest, 127(6):1919-27.
PMID: 15947303
Species: Human
Sample Types: Plasma

Rouy D et al. (2005-01-01), Plasma storage at -80 degrees C does not protect matrix metalloproteinase-9 from degradation. Anal. Biochem., 338(2):294-8.
PMID: 15745750
Species: Human
Sample Types: Plasma

Niessner A et al. (2005-01-01), Endurance training reduces circulating inflammatory markers in persons at risk of coronary events: impact on plaque stabilization? Atherosclerosis, 186(1):160-5.
PMID: 16084517
Species: Human
Sample Types: Sputum

Simpson JL et al. (2005-01-01), Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma. Am. J. Respir. Crit. Care Med., 172(5):559-65.
PMID: 15901607
Species: Human
Sample Types: Urine

Laudanski P et al. (2004-01-01), Matrix metalloprotenase-9 in acute pyelonephritis. Pediatr. Res., 55(2):357; author r.
PMID: 14763447
Species: Human
Sample Types: Serum

Jumper C et al. (2004-01-01), Determination of the serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in patients with either advanced small-cell lung cancer or non-small-cell lung cancer prior to treatment. Respir Med, 98(2):173-7.
PMID: 14971882
Species: Human
Sample Types: Cell Culture Supernates

Li DQ et al. (2004-01-01), Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells. Invest. Ophthalmol. Vis. Sci., 45(12):4302-11.
PMID: 15557436
Species: Human
Sample Types: Cell Culture Supernates

Singh S et al. (2004-01-01), CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. Lab. Invest., 84(12):1666-76.
PMID: 15467730
Species: Human
Sample Types: Follicular Fluid

D&amp;apos;Ascenzo S et al. (2004-01-01), Intrafollicular expression of matrix metalloproteinases and their inhibitors in normally ovulating women compared with patients undergoing in vitro fertilization treatment. Eur. J. Endocrinol., 151(1):87-91.
PMID: 15248826
Species: Human
Sample Types: Serum

Marx N et al. (2003-01-01), Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease. Arterioscler. Thromb. Vasc. Biol., 23(2):283-8.
PMID: 12588772
Species: Primate
Sample Types: Tissue Homogenates

Young KA et al. (2003-01-01), Gonadotropin and steroid regulation of matrix metalloproteinases and their endogenous tissue inhibitors in the developed corpus luteum of the rhesus monkey during the menstrual cycle. Biol. Reprod., 70(1):244-52.
PMID: 13679308
Species: Human
Sample Types: Serum

Ulrich D et al. (2003-01-01), Matrix metalloproteinases and tissue inhibitors of metalloproteinases in sera and tissue of patients with Dupuytren's disease. Plast. Reconstr. Surg., 112(5):1279-86.
PMID: 14504511
Species: Human
Sample Types: Serum

Doubrovina ES et al. (2003-01-01), Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J. Immunol., 171(12):6891-9.
PMID: 14662896
Species: Human
Sample Types: Serum

Tziakas DN et al. (2003-01-01), Anti-inflammatory cytokine profile in acute coronary syndromes: behavior of interleukin-10 in association with serum metalloproteinases and proinflammatory cytokines. Int. J. Cardiol., 92(2):169-75.
PMID: 14659849
Species: Human
Sample Types: Pleural Effusion

D&amp;apos;Agostino P (2003-01-01), Matrix metalloproteinases production in malignant pleural effusions after talc pleurodesis. Clin. Exp. Immunol., 134(1):138-42.
PMID: 12974766
Species: Human
Sample Types: Saliva

Fireman E et al. (2002-01-01), Induced sputum-retrieved matrix metalloproteinase 9 and tissue metalloproteinase inhibitor 1 in granulomatous diseases. Clin. Exp. Immunol., 130(2):331-7.
PMID: 12390324
Species: Human
Sample Types: Sputum

Cataldo DD et al. (2002-01-01), Matrix metalloproteinase-9, but not tissue inhibitor of matrix metalloproteinase-1, increases in the sputum from allergic asthmatic patients after allergen challenge. Chest, 122(5):1553-9.
PMID: 12426252
Species: Human
Sample Types: Peritoneal Fluid

Szamatowicz J et al. (2002-01-01), Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1: a possible role in the pathogenesis of endometriosis. Hum. Reprod., 17(2):284-8.
PMID: 11821264

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Human MMP-9 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Urine

Verified Customer | Posted 11/16/2022

urine samples should maybe be concentrated
Human MMP-9 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 11/02/2022
Human MMP-9 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: 3A-sub E human placenta cell line,A375 human melanoma cell line

Verified Customer | Posted 09/25/2020
Human MMP-9 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Human Aortic Endothelial Cells

Verified Customer | Posted 03/21/2019
Human MMP-9 Quantikine ELISA Kit

Name: Leo Zhelnin

Sample Tested: Cell culture supernatant,LX2

Verified Customer | Posted 11/13/2018
Human MMP-9 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 06/19/2018
Human MMP-9 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: HT-29 human colon adenocarcinoma cell line,LoVo human colorectal adenocarcinoma cell line,NCI-N87 human gastric carcinoma cell line,SCC-25 human tongue carcinoma cell line,SK-OV-3 human ovarian adenocarcinoma cell line

Verified Customer | Posted 04/30/2018
Human MMP-9 Quantikine ELISA Kit

Name: Leslie Priddy

Sample Tested: Serum

Verified Customer | Posted 03/30/2018
Human MMP-9 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 05/22/2017

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Human MMP-9 Quantikine ELISA Kit

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Human MMP-9 Quantikine ELISA Kit

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