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8 results for "mGluR4 Small Molecules and Peptides" in Products

mGluR4: Small Molecules and Peptides

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence ...

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Selective group III mGlu agonist

Chemical Name: L-(+)-2-Amino-4-phosphonobutyric acid
Purity: ≥99% (HPLC)
Selective group III mGlu agonist

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Chemical Name: 2-Methyl-6-(phenylethynyl)pyridine hydrochloride
Purity: ≥98% (HPLC)
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Potent and highly selective group II mGlu agonist

Chemical Name: (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Purity: ≥98% (HPLC)
Potent and highly selective group II mGlu agonist

Potent group III mGlu antagonist

Chemical Name: (RS)-α-Cyclopropyl-4-phosphonophenylglycine
Purity: ≥98% (HPLC)
Potent group III mGlu antagonist

Potent group I mGlu antagonist

Chemical Name: N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide
Purity: ≥98% (HPLC)
Potent group I mGlu antagonist

Active metabolite of oxcarbazepine (Cat. No. 3864)

Alternate Names: GP 47779
Chemical Name: 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide
Purity: ≥98% (HPLC)
Active metabolite of oxcarbazepine (Cat. No. 3864)

Positive allosteric modulator of group I mGlu receptors

Chemical Name: (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester
Purity: ≥98% (HPLC)
Positive allosteric modulator of group I mGlu receptors

Selective positive allosteric modulator of group III mGlu receptors

Alternate Names: ML 396
Chemical Name: N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide
Purity: ≥98% (HPLC)
Selective positive allosteric modulator of group III mGlu receptors
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