8 results for "mGluR4 Small Molecules and Peptides" in Products
mGluR4: Small Molecules and Peptides
The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence ...
Selective group III mGlu agonist
| Chemical Name: | L-(+)-2-Amino-4-phosphonobutyric acid |
| Purity: | ≥99% (HPLC) |
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
| Chemical Name: | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and highly selective group II mGlu agonist
| Chemical Name: | (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent group III mGlu antagonist
| Chemical Name: | (RS)-α-Cyclopropyl-4-phosphonophenylglycine |
| Purity: | ≥98% (HPLC) |
Potent group I mGlu antagonist
| Chemical Name: | N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide |
| Purity: | ≥98% (HPLC) |
Active metabolite of oxcarbazepine (Cat. No. 3864)
| Alternate Names: | GP 47779 |
| Chemical Name: | 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of group I mGlu receptors
| Chemical Name: | (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester |
| Purity: | ≥98% (HPLC) |
Selective positive allosteric modulator of group III mGlu receptors
| Alternate Names: | ML 396 |
| Chemical Name: | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
