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Leptin/OB Products

Leptin, also known as OB, is a polypeptide hormone that regulates adipose tissue mass and energy balance. In mice (ob/ob) and humans, inactivating mutations of the OB gene can cause obesity. Leptin signals through the transmembrane Leptin R in the hypothalamus but can also bind shorter and soluble forms of Leptin R which do not signal. Adipocytes increase Leptin expression as cell size increases, resulting in depressed appetite and increased energy expenditure. Low Leptin levels prompt increased appetite and decreased energy expenditure. Leptin can also block the onset of puberty or menses during starvation, extreme exercise-induced weight loss, anorexia, or cancer-induced cachexia.

31 results for "Leptin/OB" in Products

Leptin/OB Products

Leptin, also known as OB, is a polypeptide hormone that regulates adipose tissue mass and energy balance. In mice (ob/ob) and humans, inactivating mutations of the OB gene can cause obesity. Leptin signals through the transmembrane Leptin R in the hypothalamus but can also bind shorter and soluble forms of Leptin R which do not signal. Adipocytes increase Leptin expression as cell size increases, resulting in depressed appetite and increased energy expenditure. Low Leptin levels prompt increased appetite and decreased energy expenditure. Leptin can also block the onset of puberty or menses during starvation, extreme exercise-induced weight loss, anorexia, or cancer-induced cachexia.

31 results for "Leptin/OB" in Products

Catalog #: 898249

Control for use with Human Leptin/OB Simple Plex Cartridge Kit

WB, IHC, Neut
WB, IHC, Neut
WB
WB, ELISA, IHC

Recombinant Monoclonal Antibody.

ELISA, Neut

Recombinant Monoclonal Antibody.

ELISA

Simple Plex Human Leptin/OB assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Catalog #: QC264
Ctrl

For use with catalog number QK398

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

ELISA
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