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JNK Products
Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.
14 results for "JNK" in Products
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JNK Products
Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.
14 results for "JNK" in Products
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunohistochemistry, Simple Western, Western Blot |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunohistochemistry, Simple Western, Western Blot |
| Assay Range : | 156 - 10,000 pg/mL |
| Applications : | ELISA |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #1006A |
| Applications : | Immunocytochemistry/Immunofluorescence, Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #252355 |
| Applications : | Simple Western, Western Blot |
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
JNK, SAPK and p38 activator
| Chemical Name : | (2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate |
| Purity : | ≥98% (HPLC) |
Selective JNK inhibitor
| Chemical Name : | Anthra[1-9-cd]pyrazol-6(2H)-one |
| Purity : | ≥98% (HPLC) |
Contains 4 membranes - each spotted in duplicate with 26 different cell stress antibodies
Inhibitor of JNK signaling
| Chemical Name : | (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester |
| Purity : | ≥97% (HPLC) |
Selective, competitive JNK inhibitor
| Chemical Name : | 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one |
| Purity : | ≥99% (HPLC) |
Selective JNK inhibitor
| Alternate Names : | Halicin |
| Chemical Name : | 5-[(5-Nitro-2-thiazolyl)thio]-1,3,4thiadiazol-2-amine |
| Purity : | ≥99% (HPLC) |
High affinity JNK inhibitor; also inhibits HCMV replication
| Chemical Name : | 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride |
| Purity : | ≥98% (HPLC) |
Peptide inhibitor of JNK/c-Jun interaction
| Purity : | ≥95% (HPLC) |
