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Integrin alpha V beta 3 Products
Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of aVb3 function during osteoclastogenesis causes osteoporosis. In addition, aVb3 enhances VEGF R2 mediated angiogenesis, IGF-1 mediated tumor cell invasiveness, and cell entry by several viruses.
22 results for "Integrin alpha V beta 3" in Products
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Integrin alpha V beta 3 Products
Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of aVb3 function during osteoclastogenesis causes osteoporosis. In addition, aVb3 enhances VEGF R2 mediated angiogenesis, IGF-1 mediated tumor cell invasiveness, and cell entry by several viruses.
22 results for "Integrin alpha V beta 3" in Products
Bind
| Source : | CHO |
| Accession # : | NP_002201 (Integrin alpha V) & AAA52589 (Integrin beta 3) |
| Applications : | Binding Activity |
Catalog #:
MAB3050
Flow, IHC, IP, AdBlk, CyTOF-ready
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
| Purity : | ≥95% (HPLC) |
Catalog #:
7889-AV
BA
| Source : | CHO |
| Accession # : | P43406 (Integrin alpha V) & O54890 (Integrin beta 3) |
| Applications : | Bioactivity |
Catalog #:
FAB3050T
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
10426-AV
BA
| Source : | CHO |
| Accession # : | XP_005573729.1 (Integrin alpha V) & XP_005584667.1 (Int |
| Applications : | Bioactivity |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
FAB12192G
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | Flow Cytometry |
Catalog #:
FAB12192V
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | Flow Cytometry |
Catalog #:
FAB12192U
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | Flow Cytometry |
Catalog #:
FAB12192N
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | Flow Cytometry |
Catalog #:
MAB12192
Flow, CyTOF-ready
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | CyTOF-ready, Flow Cytometry |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
FAB3050N
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
FAB3050R
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
FAB12192R
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | Flow Cytometry |
Catalog #:
FAB3050V
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
FAB3050S
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
FAB3050U
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #23C6 |
| Applications : | Flow Cytometry |
Catalog #:
FAB12192T
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | Flow Cytometry |
Catalog #:
FAB12192S
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2549B |
| Applications : | Flow Cytometry |
