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Integrin alpha V beta 3 Products

Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of aVb3 function during osteoclastogenesis causes osteoporosis. In addition, aVb3 enhances VEGF R2 mediated angiogenesis, IGF-1 mediated tumor cell invasiveness, and cell entry by several viruses.

22 results for "Integrin alpha V beta 3" in Products

Integrin alpha V beta 3 Products

Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of aVb3 function during osteoclastogenesis causes osteoporosis. In addition, aVb3 enhances VEGF R2 mediated angiogenesis, IGF-1 mediated tumor cell invasiveness, and cell entry by several viruses.

22 results for "Integrin alpha V beta 3" in Products

Flow, IHC, IP, AdBlk, CyTOF-ready

αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor

BA
Catalog #: FAB3050T
Flow
BA
Catalog #: FAB12192G
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB12192V
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB12192U
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB12192N
Flow

Recombinant Monoclonal Antibody.

Flow, CyTOF-ready

Recombinant Monoclonal Antibody.

Catalog #: FAB3050N
Flow
Catalog #: FAB3050R
Flow
Catalog #: FAB12192R
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB3050V
Flow
Catalog #: FAB3050S
Flow
Catalog #: FAB3050U
Flow
Catalog #: FAB12192T
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB12192S
Flow

Recombinant Monoclonal Antibody.

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