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IL-23 Products
IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.
26 results for "IL-23" in Products
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IL-23 Products
IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.
26 results for "IL-23" in Products
| Source : | Sf 21 (baculovirus) |
| Accession # : | P29460 (p40) & AAG37232 (p19) |
| Applications : | Bioactivity |
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
| Source : | CHO |
| Applications : | Bioactivity |
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications : | ELISA |
Sf21-Expressed
| Source : | Sf 21 (stably transfected) |
| Accession # : | P43432 (p40) & Q9EQ14 (p19) |
| Applications : | Bioactivity |
| Sensitivity : | 16.3 pg/mL |
| Assay Range : | 39 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG2b Clone #1193B |
| Applications : | Block/Neutralize, Western Blot |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #727753 |
| Applications : | ELISA, Western Blot |
| Sensitivity : | 4.17 pg/mL |
| Assay Range : | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, Heparin Plasma) |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Assay Range : | 39.1 - 2,500 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #320234 |
| Applications : | ELISA Capture, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #320229 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
| Source : | Sf 21 (baculovirus) |
| Accession # : | NP_072133 (p40) & NP_569094 (p19) |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #320244 |
| Applications : | Flow Cytometry |
