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IGFBP-1 Products

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

23 results for "IGFBP-1" in Products

IGFBP-1 Products

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

23 results for "IGFBP-1" in Products

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies

Simple Plex Cartridge Kit for quantitation of IGFBP-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies

Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies

WB, IHC

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

WB
WB
WB, Simple Western
BA
Catalog #: QC204
ELISA, Ctrl

For use with catalog number DGB100

Catalog #: 898347

Control for use with Human IGFBP-1 Simple Plex Cartridge Kit

WB
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