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IGFBP-1 Products
The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.
23 results for "IGFBP-1" in Products
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IGFBP-1 Products
The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.
23 results for "IGFBP-1" in Products
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
Catalog #:
SPCKB-PS-000327
Simple Plex Cartridge Kit for quantitation of IGFBP-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
ELISA
| Sensitivity : | 13.8 pg/mL |
| Assay Range : | 125 - 8,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine, Human Milk) |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
WB, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
ELISA
| Assay Range : | 23.4 - 1,500 pg/mL |
| Applications : | ELISA |
BA
| Source : | NS0 |
| Accession # : | P08833 |
| Applications : | Bioactivity |
High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
| Chemical Name : | 1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid |
| Purity : | ≥98% (HPLC) |
WB, Neut
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33627 |
| Applications : | Block/Neutralize, ELISA Capture, Western Blot |
ELISA
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB1240
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #176110 |
| Applications : | Western Blot |
Catalog #:
BAF871
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
WB, Simple Western
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Simple Western, Western Blot |
Catalog #:
1588-B1
BA
| Source : | NS0 |
| Accession # : | P47876 |
| Applications : | Bioactivity |
Catalog #:
BAF1240
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
