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HGFR/c-MET Products

HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron. Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.

245 results for "HGFR/c-MET" in Products

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HGFR/c-MET Products

HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron. Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.

245 results for "HGFR/c-MET" in Products

WB, Simple Western, Flow, IHC, Block, CyTOF-ready, ICC, KO
WB, IHC, Block, ICC
WB, Simple Western, IHC, CyTOF-reported, ICC, ICFlow
Flow, CyTOF-ready
Flow, ICC/IF, IHC

Simple Plex Human HGFR/c-MET assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

WB, IHC
WB, KO
WB, Block
Catalog #: MAB5271
WB, IHC, ICC
WB, IHC, ICC
Catalog #: 8614-MT
BA

(HEK293-expressed)

Bind
Catalog #: 898327
Ctrl

Control for use with Human HGFR/c-MET Simple Plex Cartridge Kit

Results Per Page
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