Sign In / Register
HGFR/c-MET Products
HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron. Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.
53 results for "HGFR/c-MET" in Products
Search
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
HGFR/c-MET Products
HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron. Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.
53 results for "HGFR/c-MET" in Products
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Knockout Validated, Simple Western, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #95106 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
| Source : | NS0 |
| Accession # : | P08581 |
| Applications : | Binding Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #95106 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Flow Cytometry, Western Blot |
Simple Plex Human HGFR/c-MET assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #95106 |
| Applications : | Flow Cytometry |
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Applications : | ELISA |
(HEK293-expressed)
| Source : | HEK293 |
| Accession # : | P08581 (HGF R alpha ) & P08581 (HGF R beta ) |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #85503 |
| Applications : | ELISA Capture, Immunocytochemistry/Immunofluorescence, Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, ELISA Capture, Western Blot |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #95106 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #95308 |
| Applications : | Immunohistochemistry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #95106 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #95106 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #118627 |
| Applications : | ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #527125 |
| Applications : | Knockout Validated, Western Blot |
