5 results for "GPER/GPR30 Small Molecules and Peptides" in Products
GPER/GPR30: Small Molecules and Peptides
GPR30 a former orphan receptor has been linked to estrogen-mediated activation of adenylyl cyclase, release of epidermal growth factor (EGF)-related ligands, and specific estrogen binding.1 GPR30 acts independently of estrogen receptors, ERalpha and ERbeta, to release of heparin-binding EGF and may play a role in breast cancer tumorogenesis.
Potent and selective GPER agonist
| Chemical Name: | (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]- ethanone |
| Purity: | ≥98% (HPLC) |
Selective GPER antagonist
| Chemical Name: | (±)-(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline |
| Purity: | ≥98% (HPLC) |
Potent G protein-coupled estrogen receptor (GPER) agonist
| Chemical Name: | N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-5-(tetrahydro-2H-pyran-2-yl)-2-furanmethanamine |
| Purity: | ≥98% (HPLC) |
Potent and selective G protein-coupled estrogen receptor (GPER) antagonist
| Chemical Name: | N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-4-methoxybenzenemethanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Estrogen receptor partial agonist/antagonist
| Chemical Name: | (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate |
| Purity: | ≥98% (HPLC) |
