GluR7/GRIK3: Small Molecules and Peptides
Glutamate receptors, including GluR7/GRIK3, are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GluR7/GRIK3 belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. A polymorphism of GluR7/GRIK3 has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
6 results for "GluR7/GRIK3 Small Molecules and Peptides" in Products
6 results for "GluR7/GRIK3 Small Molecules and Peptides" in Products
GluR7/GRIK3: Small Molecules and Peptides
Glutamate receptors, including GluR7/GRIK3, are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GluR7/GRIK3 belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. A polymorphism of GluR7/GRIK3 has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
Broad spectrum glutamatergic antagonist
| Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
GluK1-selective kainate antagonist
| Chemical Name: | (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione |
| Purity: | ≥98% (HPLC) |
Non-competitive non-NMDA iGluR antagonist
| Chemical Name: | 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective GluK1 kainate agonist
| Chemical Name: | (RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid |
| Purity: | ≥98% (HPLC) |
Competitive non-NMDA iGluR antagonist
| Alternate Names: | MPQX |
| Chemical Name: | [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid |
| Purity: | ≥98% (HPLC) |
Non-competitive non-NMDA iGluR antagonist
| Alternate Names: | GYKI 53773,LY 300164 |
| Chemical Name: | (8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine |
| Purity: | ≥98% (HPLC) |
