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Glucagon Products
Glucagon is a pancreatic peptide hormone that plays a critical role in glucose metabolism and homeostasis. Mature Glucagon is generated from its precursor by the prohormone convertase PC2/PCSK2 in pancreatic alpha-cells. Glucagon is secreted in response to low blood glucose (hypoglycemia) and downregulated in response to high blood glucose (hyperglycemia). Glucagon production is under the control of both hormones and neurotransmitters. Glucagon inhibits Insulin secretion, and vice versa. Glucagon stimulates hepatic gluconeogenesis and glycogenolysis, thereby increasing blood glucose. Like insulin, Glucagon is dysregulated in type 2 diabetes (T2D) and contributes to its pathology.
15 results for "Glucagon" in Products
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Glucagon Products
Glucagon is a pancreatic peptide hormone that plays a critical role in glucose metabolism and homeostasis. Mature Glucagon is generated from its precursor by the prohormone convertase PC2/PCSK2 in pancreatic alpha-cells. Glucagon is secreted in response to low blood glucose (hypoglycemia) and downregulated in response to high blood glucose (hyperglycemia). Glucagon production is under the control of both hormones and neurotransmitters. Glucagon inhibits Insulin secretion, and vice versa. Glucagon stimulates hepatic gluconeogenesis and glycogenolysis, thereby increasing blood glucose. Like insulin, Glucagon is dysregulated in type 2 diabetes (T2D) and contributes to its pathology.
15 results for "Glucagon" in Products
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications : | ELISA |
| Sensitivity : | 14.7 pg/mL |
| Assay Range : | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Endogenous glucagon receptor agonist
| Purity : | ≥95% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Flow Cytometry |
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
Negative allosteric modulator of glucagon and GLP-1 receptors
| Chemical Name : | 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-ylbenzamide |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Immunocytochemistry/Immunofluorescence |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #181402 |
| Applications : | Flow Cytometry |
