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GDNF Products

GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.

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215 results for "GDNF" in Products

215 results for "GDNF" in Products

GDNF Products

GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.

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Analyzed by SEC-MALS

Source: NS0
Accession #: P39905
Applications: BA, Bind
(3)

Analyzed by SEC-MALS

Source: NS0
Accession #: P39905.1
Applications: BA, Bind
Recombinant Human GDNF GMP Protein Bioactivity
(2)
Sensitivity: 0.696 pg/mL
Applications: ELISA
Assay Range: 4.69 - 300 pg/mL (Cell Culture Supernates, Cell Lysates, Tissue Lysates, Serum, Plasma, EDTA Plasma, Heparin Plasma)
Human GDNF Standard Curve
(2)
Assay Range: 31.2 - 2,000 pg/mL
Applications: ELISA
Human GDNF ELISA Standard Curve
Source: Sf 21 (baculovirus)
Accession #: Q07731
Applications: BA, Bind
Recombinant Rat GDNF Protein Bioactivity
(2)

Control for use with Human GDNF Simple Plex Assay Cartridge Kit

Simple Plex Human GDNF assay kit for use on Ella instrument. Contains cartridge, Sample Diluent SD13, and Wash Buffer.

Simple Plex Discovery Human GDNF Ella Assay
(3)
Source: E. coli
Accession #: NP_000505.1
Applications: BA
(3)
Reactivity: Human, Rat
Details: Goat IgG Polyclonal
Applications: WB, Neut
Source: E. coli
Accession #: NP_000505.1
Applications: BA
(2)
Source: E. coli
Accession #: NP_000505.1
Applications: BA
(3)

Recombinant Monoclonal Antibody

Reactivity: Human
Details: Rabbit IgG Monoclonal Clone #11D2
Applications: IHC, WB, ELISA, Flow, IP
GDNF Antibody (11D2)
(5)

For use with catalog number DGD00

Source: E. coli
Accession #: P39905.1
Applications: BA
(2)
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