
GDNF Products
GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.
13 results for "GDNF" in Products
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GDNF Products
GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.
13 results for "GDNF" in Products
Source : | NS0 |
Accession # : | P39905 |
Applications : | Binding Activity, Bioactivity |
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Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Source : | NS0 |
Accession # : | P39905.1 |
Applications : | Binding Activity, Bioactivity |
Assay Range : | 31.2 - 2,000 pg/mL |
Applications : | ELISA |
Source : | Sf 21 (baculovirus) |
Accession # : | Q07731 |
Applications : | Binding Activity, Bioactivity |
Sensitivity : | 0.696 pg/mL |
Assay Range : | 4.69 - 300 pg/mL (Cell Culture Supernates, Cell Lysates, Tissue Lysates, Serum, Plasma, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #27106 |
Applications : | ELISA Capture, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #27106R |
Applications : | ELISA Capture |