8 results for "GABA-A Receptor Antagonists Small Molecules and Peptides" in Products
GABA-A Receptor Antagonists: Small Molecules and Peptides
GABAA Receptor Subunits
The majority of human endogenous GABAA receptors are composed of α1-, β2- and γ2-subunits in a 2:2:1 ratio (α2β2γ), however the exact subunit conformation is determined by the expression of different subunits in a given cell type. Some subunits are only expressed in specific brain areas, for example receptors containing the α2-subunit are found in regions where the α1-subunit is absent or expressed at low levels, such as the ...
GABAA antagonist
| Purity: | ≥97% (HPLC) |
GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
| Chemical Name: | [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride |
| Purity: | ≥98% (HPLC) |
Competitive and selective GABAA antagonist
| Alternate Names: | Gabazine |
| Chemical Name: | 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide |
| Purity: | ≥98% (HPLC) |
GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
| Chemical Name: | [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium iodide |
| Purity: | ≥98% (HPLC) |
GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
| Chemical Name: | [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide |
| Purity: | ≥98% (HPLC) |
Potent GABAA antagonist
| Chemical Name: | [R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one |
| Purity: | ≥98% (HPLC) |
Non-selective P2 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥98% (HPLC) |
Na+/2Cl-/K+ (NKCC) symporter inhibitor; also GABAA antagonist
| Chemical Name: | 5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoic acid |
| Purity: | ≥98% (HPLC) |
