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(-)-Bicuculline methochloride

GABA-A Receptor Antagonists Small Molecule
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Key Product Details

Description: GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
Chemical Name: [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride
Purity: ≥99% (HPLC)
Molecular Weight: 417.85

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Citations (23)

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  • Increased excitability with GABAA antagonism
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Organotypic Hippocampus Slices
    Bath application of Bicuculline methochloride increased overall excitation of neurons in slice.

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