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Dopamine D1R/DRD1: Small Molecules and Peptides

DRD1 is the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G protein-coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events.

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12 results for "Dopamine D1R/DRD1 Small Molecules and Peptides" in Products

12 results for "Dopamine D1R/DRD1 Small Molecules and Peptides" in Products

Dopamine D1R/DRD1: Small Molecules and Peptides

DRD1 is the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G protein-coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events.

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Endogenous agonist at dopamine D1-5 receptors

Chemical Name: 3,4-Dihydroxyphenethylamine hydrochloride
Purity: ≥99% (HPLC)
Endogenous agonist at dopamine D1-5 receptors

Caged dopamine; photolysed by UV light

Purity: ≥98% (HPLC)
Caged dopamine; photolysed by UV light

Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker

Alternate Names: (R)-(+)-SCH 23390 hydrochloride
Chemical Name: (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
Purity: ≥98% (HPLC)
Selective D1-like antagonist; also 5-HT2C  agonist and Kir3 channel blocker

Dopamine precursor

Alternate Names: Levodopa
Chemical Name: L-3,4-Dihydroxyphenylalanine
Purity: ≥98% (HPLC)
Dopamine precursor

D1 agonist

Chemical Name: (±)-6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine hydrobromide
Purity: ≥98% (HPLC)
D1 agonist

Selective D1-like agonist

Chemical Name: (±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide
Purity: ≥98% (HPLC)
Selective D1-like agonist

Selective D1-like agonist

Chemical Name: (±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride
Purity: ≥98% (HPLC)
Selective D1-like agonist

High affinity D1-like antagonist

Alternate Names: Ecopipam hydrobromide
Chemical Name: (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide
Purity: ≥98% (HPLC)
High affinity D1-like antagonist

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98% (HPLC)
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Potent and selective D1-like agonist; orally active

Chemical Name: (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride
Purity: ≥98% (HPLC)
Potent and selective D1-like agonist; orally active

Potent and selective D1-like agonist

Chemical Name: cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
Purity: ≥98% (HPLC)
Potent and selective D1-like agonist

Selective D1-like partial agonist

Alternate Names: SKF 82526
Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol hydrochloride
Purity: ≥98% (HPLC)
Selective D1-like partial agonist
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