Dihydrexidine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0884

Selective D1-like agonist
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Key Product Details

Description

Selective D1-like agonist

View all Dopamine D1 and D5 Receptor Agonists »

Product Description

Dihydrexidine hydrochloride is an a potent, full efficacy dopamine D1 agonist which shows no agonist activity at peripheral D2 receptors or adrenoceptors at doses which cause maximal stimulation of D1 sites. The compound appears to be fully bioavailable in brain and exhibits profound antiparkinsonism effects in vivo.

Licensing Information

Sold under license, US Patent 5,047,536

Product Specifications

Molecular Weight

303.79

Formula

C17H17NO2.HCl

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

(±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride

CAS Number

137417-08-4

PubChem ID

11403931

InChI Key

IJYUPBNUPIRQEP-SATBOSKTSA-N

SMILES

OC1=C(O)C=C(CC[C@]3([H])[C@@]([H])2C4=C(C=CC=C4)CN3)C2=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 3.04 10
DMSO 15.19 50

Preparing Stock Solutions for Dihydrexidine hydrochloride

The following data is based on the product molecular weight 303.79

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 6.58 mL 32.92 mL 65.83 mL
2.5 mM 1.32 mL 6.58 mL 13.17 mL
5 mM 0.66 mL 3.29 mL 6.58 mL
25 mM 0.13 mL 0.66 mL 1.32 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Dihydrexidine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Dihydrexidine hydrochloride

For research use only

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