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CRF1 Receptor Antagonists: Small Molecules and Peptides

CRHR1, also known as CHR-R1 and Corticotropin Releasing Factor Receptor 1, CRF 1, is a member of the Class B G protein-coupled receptor family that mediates the action of hypothalamic and peripheral CRH. It is the key regulator of the stress response in the hypothalamic-pituitary adrenal axis and an important functional mediator of the endocrine, cardiovascular, gastrointestinal, and immune systems. The other major endogenous ligand for CRHR1 is Urocortin 1.

7 results for "CRF1 Receptor Antagonists Small Molecules and Peptides" in Products

CRF1 Receptor Antagonists: Small Molecules and Peptides

CRHR1, also known as CHR-R1 and Corticotropin Releasing Factor Receptor 1, CRF 1, is a member of the Class B G protein-coupled receptor family that mediates the action of hypothalamic and peripheral CRH. It is the key regulator of the stress response in the hypothalamic-pituitary adrenal axis and an important functional mediator of the endocrine, cardiovascular, gastrointestinal, and immune systems. The other major endogenous ligand for CRHR1 is Urocortin 1.

7 results for "CRF1 Receptor Antagonists Small Molecules and Peptides" in Products

Selective, non-peptide CRF1 antagonist

High affinity CRF1 antagonist; orally bioavailable

Potent and selective CRF1 antagonist

Potent and selective CRF1 antagonist; anxiolytic

Potent and selective CRF1 antagonist; binds at an allosteric site

CRF1 antagonist

Selective non-peptide CRF1 antagonist

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