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Clusterin Products
Clusterin, also known as Apolipoprotein J, Sulfated Glycoprotein 2 (SGP-2), TRPM-2, and SP-40,40, is a secreted multifunctional protein that binds a wide range of molecules and may function as a chaperone of misfolded extracellular proteins. It also participates in the control of cell proliferation, apoptosis, and carcinogenesis. Clusterin is predominantly expressed in adult testis, ovary, adrenal gland, liver, heart, and brain and in many epithelial tissues during embryonic development. It is secreted as a disulfide-linked heterodimer of alpha and beta chains and circulates as a component of high density lipoprotein (HDL) particles. Clusterin exerts tissue protective functions in atherosclerosis and Alzheimer’s disease by binding and neutralizing non-oxidatively modified LDL reduces cytotoxicity and beta-amyloid fibrils, respectively. Increased circulating levels of Clusterin enhance tumor aggressiveness by inhibiting apoptosis and by promoting epithelial to mesenchymal transition.
24 results for "Clusterin" in Products
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Clusterin Products
Clusterin, also known as Apolipoprotein J, Sulfated Glycoprotein 2 (SGP-2), TRPM-2, and SP-40,40, is a secreted multifunctional protein that binds a wide range of molecules and may function as a chaperone of misfolded extracellular proteins. It also participates in the control of cell proliferation, apoptosis, and carcinogenesis. Clusterin is predominantly expressed in adult testis, ovary, adrenal gland, liver, heart, and brain and in many epithelial tissues during embryonic development. It is secreted as a disulfide-linked heterodimer of alpha and beta chains and circulates as a component of high density lipoprotein (HDL) particles. Clusterin exerts tissue protective functions in atherosclerosis and Alzheimer’s disease by binding and neutralizing non-oxidatively modified LDL reduces cytotoxicity and beta-amyloid fibrils, respectively. Increased circulating levels of Clusterin enhance tumor aggressiveness by inhibiting apoptosis and by promoting epithelial to mesenchymal transition.
24 results for "Clusterin" in Products
Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies
Catalog #:
ARY012
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
ELISA
| Sensitivity : | 1.05 ng/mL |
| Assay Range : | 3.12 - 200 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
| Applications : | ELISA |
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
Catalog #:
ARY019
Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
ELISA
| Sensitivity : | 0.094 ng/mL |
| Assay Range : | 0.781 - 50 ng/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
Catalog #:
FCSTM16
ELISA
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications : | ELISA |
Catalog #:
MAB29372
IHC
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #350270 |
| Applications : | ELISA Capture, Immunohistochemistry |
Catalog #:
SPCKB-PS-001512
Simple Plex Cartridge Kit containing Clusterin for use with Human Plasma/Serum/Urine. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
WB, IHC, IP
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Capture, Immunohistochemistry, Immunoprecipitation, Western Blot |
ELISA
| Assay Range : | 0.469 - 30 ng/mL |
| Applications : | ELISA |
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
Catalog #:
BAM29373
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #350207 |
| Applications : | ELISA Detection |
Catalog #:
BAF2937
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
WB, IHC, IP
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Immunoprecipitation, Western Blot |
Catalog #:
AF7084
WB, IHC
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Immunohistochemistry, Western Blot |
Catalog #:
MAB2937
WB, IHC, IP
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #350227 |
| Applications : | Immunohistochemistry, Immunoprecipitation, Western Blot |
Catalog #:
2747-HS
BA
| Source : | NS0 |
| Accession # : | Q06890 |
| Applications : | Bioactivity |
BA
| Source : | NS0 |
| Accession # : | NP_001822 |
| Applications : | Bioactivity |
Catalog #:
MAB29373
ELISA
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #350207 |
| Applications : | ELISA |
Catalog #:
LHK2937
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Sensitivity : | 64.3 pg/mL |
| Assay Range : | 664 - 483,800 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Urine) |
