Simple Plex Human Clusterin Cartridge
ProteinSimple, part of Bio-Techne | Catalog # SPCKB-PS-001512
Customize Your Simple Plex Cartridge
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and add up to 8 analytes per cartridge.
Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Simple Plex Human Clusterin Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Reactivity
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested multiple times in one Clusterin assay.
Inter-Assay Precision (Precision between assays) Replicates of each Clusterin control were tested in multiple assays performed by at least three technicians using two lots of reagents for human Clusterin.
EDTA Plasma, Heparin Plasma, Serum, Urine
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 44 | 43 |
| Mean (pg/mL) | 2303 | 103,870 | 2317 | 111,162 |
| Standard Deviation | 101 | 4562 | 260 | 8163 |
| CV% | 4.4 | 4.4 | 11.2 | 7.3 |
Recovery for Simple Plex Human Clusterin Cartridge
Recovery was not necessary as human Clusterin shows 5 points of natural linearity.
Linearity
Samples containing and/or spiked with high concentrations of human Clusterin were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay
Scientific Data Images for Simple Plex Human Clusterin Cartridge
Simple Plex Human Clusterin Assay Standard Curve
Data shown represents typical performance results for Lower Limit of Quantitation (LLOQ) and Upper Limit of Quantitation (ULOQ) for Simple Plex Human Clusterin Assay. Assay range is 40.5-386,400 pg/mL.Preparation and Storage
Shipping
Stability & Storage
Background: Clusterin
Clusterin, also known as Apolipoprotein J, Sulfated Glycoprotein 2 (SGP-2), TRPM-2, and SP-40,40, is a secreted multifunctional protein that binds a wide range of molecules and may function as a chaperone of misfolded extracellular proteins. It also participates in the control of cell proliferation, apoptosis, and carcinogenesis. Clusterin is predominantly expressed in adult testis, ovary, adrenal gland, liver, heart, and brain and in many epithelial tissues during embryonic development. It is secreted as a disulfide-linked heterodimer of alpha and beta chains and circulates as a component of high density lipoprotein (HDL) particles. Clusterin exerts tissue protective functions in atherosclerosis and Alzheimer’s disease by binding and neutralizing non-oxidatively modified LDL reduces cytotoxicity and beta-amyloid fibrils, respectively. Increased circulating levels of Clusterin enhance tumor aggressiveness by inhibiting apoptosis and by promoting epithelial to mesenchymal transition.
Alternate Names
Gene Symbol
Additional Clusterin Products
Product Documents for Simple Plex Human Clusterin Cartridge
Product Specific Notices for Simple Plex Human Clusterin Cartridge
For research use only