186 results for "CDK4" in Products
CDK4 Products
Cyclin-dependent Kinase 4 (CDK4) is a 303 amino acid (aa) member of the Ser/Thr kinase family with a predicted molecular weight of 33.7 kDa. The human protein shares 94% and 95% aa sequence identity with the mouse and rat orthologs, respectively. CDK4 shuttles between the cytoplasm and nucleus as part of its role in cell cycle regulation. It promotes the transition from G1 to S phase by phosphorylating and inactivating RB1. Activation of CDK4 requires binding of a D-type Cyclin and ...
Recombinant Monoclonal Antibody
Protein kinase C inhibitor
Recombinant Monoclonal Antibody
Potent cdk4 and cdk6 inhibitor; brain penetrant
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
Cdk inhibitor; potently inhibits cdk2 and cdk9
Potent HMG-CoA reductase inhibitor
HMG-CoA reductase inhibitor
SETD8 inhibitor; also CDK4 inhibitor
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody