Skip to main content

Caspase-3 Products

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.

Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.

Products:

Show More

123 results for "Caspase-3" in Products

Back to Search Results
Apply

Search

Caspase-3 Products

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.

Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.

Products:

Show More

123 results for "Caspase-3" in Products

CyTOF-ready, Flow, HC, ICC/IF, IHC, KD, KO, MS, Simple Western, WB
WB, IHC, ICC, ICFlow
Flow, ICC/IF, IHC, IP, WB
ICC/IF, IHC, IP, Simple Western, WB

Potent pro-apoptotic anticancer agent; activates caspase-3

ChIP, IHC, IP, Simple Western, WB
WB, Simple Western, IP, KO

Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies

ICC/IF, IHC, WB
ELISA, ICC/IF, IHC, WB

Recombinant monoclonal antibody expressed in HEK293F cells

ICC/IF, IHC, WB

Selective cyclooxygenase-2 (COX-2) inhibitor

Dual ISH-IHC, ICC

Recombinant Monoclonal Antibody.

Caspase-3 Inhibitor

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

ICFlow
Results Per Page
5 10 25 50
/ 5