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Caspase-3: Antibodies

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.

Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.

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104 results for "Caspase-3 Primary Antibodies" in Products

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Caspase-3: Antibodies

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.

Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.

Products:

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104 results for "Caspase-3 Primary Antibodies" in Products

CyTOF-ready, Flow, HC, ICC/IF, IHC, KD, KO, MS, Simple Western, WB
WB, IHC, ICC, ICFlow
Flow, ICC/IF, IHC, IP, WB
ICC/IF, IHC, IP, Simple Western, WB
ChIP, IHC, IP, Simple Western, WB
WB, Simple Western, IP, KO
ICC/IF, IHC, WB
ICC/IF, IHC, WB
Dual ISH-IHC, ICC

Recombinant Monoclonal Antibody.

ICFlow
Catalog #: IC835T
ICFlow
Catalog #: IC835V
ICFlow
Catalog #: IC835S
ICFlow
ICFlow
ELISA, ICC/IF, IHC, WB

Recombinant monoclonal antibody expressed in HEK293F cells

Catalog #: IC835U
ICFlow
ICC/IF, KO, WB

Recombinant Monoclonal Antibody

ELISA, IHC, WB

Recombinant monoclonal antibody expressed in HEK293F cells

ELISA, ICC/IF, IHC, WB

Recombinant Monoclonal Antibody

ELISA, IHC, WB

Recombinant monoclonal antibody expressed in HEK293F cells

ELISA, IHC, WB

Recombinant monoclonal antibody expressed in HEK293F cells

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