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66 results for "Caspase-3" in Products

Caspase-3 Products

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin. Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.

Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, ICC/IF
Caspase‑3 antibody in Jurkat Human Cell Line by Immunocytochemistry (ICC).
(37)
Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #269518
Applications:
IHC, WB, Flow, ICC/IF
Detection of Human and Mouse Cleaved Caspase‑3 (Asp175) antibody by Western Blot.
(20)
Reactivity:
Multi-Species
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, Simple Western, IP
Detection of Human and Mouse Caspase-3 antibody by Western Blot.
(5)
Reactivity:
Human, Mouse
Assay Range:
219-14000 pg/mL
Applications:
ELISA
Reactivity:
Human
Source:
E. coli
Accession #:
P42574
Applications:
Enzyme Activity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #84803
Applications:
KO, WB
Detection of Human Precursor Caspase-3 and p18 Subunit antibody by Western Blot.
(3)

Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies

Reactivity:
Human
Determination of Relative Levels of Human Apoptosis-related Proteins Using Proteome Profiler Human Apoptosis Array Kit.
(2)
Reactivity:
Human
Source:
E. coli
Accession #:
AAA65015
Applications:
Enzyme Activity
R&D Systems Recombinant Proteins and Enzymes

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #1112I
Applications:
Dual ISH-IHC, ICC/IF
Caspase-3 antibody in Jurkat Human Cell Line by Immunocytochemistry (ICC).
(2)
Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #269518
Applications:
Flow
Detection of Cleaved Caspase-3 antibody in Jurkat Human Cell Line antibody by Flow Cytometry.
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, IP
Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #269518
Applications:
Flow
Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #269518
Applications:
Flow
Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #269518
Applications:
Flow
Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #269518
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #84803
Applications:
KO, WB
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #84803
Applications:
KO, WB
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