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Caspase-1 Products

Caspase-1, also known as IL-1 beta-converting enzyme (ICE), is an aspartic protease that plays a key role in the inflammatory response and apoptosis. Caspase-1 precursor (about 50kDa) can be cleaved and the active enzyme consists of a complex of two 20 kDa and two 10 kDa subunits which associate following cleavage of inactive precursors. Caspase-1 is required for proteolytic cleavage of the IL-1 beta precursor to form the active proinflammatory cytokine.

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346 results for "Caspase-1" in Products

346 results for "Caspase-1" in Products

Caspase-1 Products

Caspase-1, also known as IL-1 beta-converting enzyme (ICE), is an aspartic protease that plays a key role in the inflammatory response and apoptosis. Caspase-1 precursor (about 50kDa) can be cleaved and the active enzyme consists of a complex of two 20 kDa and two 10 kDa subunits which associate following cleavage of inactive precursors. Caspase-1 is required for proteolytic cleavage of the IL-1 beta precursor to form the active proinflammatory cytokine.

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Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 kappa Monoclonal Clone #14F468
Applications: IHC, WB, ELISA, ICC/IF, Simple Western
Detection of Caspase-1 in HeLa Cell Lysate by Simple Western
(24)
Sensitivity: 1.24 pg/mL
Applications: ELISA
Assay Range: 6.25 - 400 pg/mL (Cell Culture Supernates)
Human Caspase-1 ELISA Standard Curve
(2)

Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.

Applications: Simple Plex
Custom Simple Plex Assay Panel

Simple Plex Human Caspase-1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Simple Plex
Ella Automated ELISA Platform and Simple Plex Human Caspace-1 Assay
(3)

Control for use with Human Caspase-1 Simple Plex Cartridge Kit

Applications: Ctrl, Simple Plex
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, KO
Knockout Validated: Caspase-1 Antibody [NB100-56564]
(3)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 kappa Monoclonal Clone #14F468
Applications: IHC, WB, Simple Western
Western Blot Analysis of Caspase-1 in Infected Mouse BMMs
(11)
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Western Blot: Caspase-1 Antibody [NBP2-15713]
(4)

High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable

Alternate Names: Belnacasan
Chemical Name: N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide
Purity: ≥98% (HPLC)
High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable
Applications: ELISA
Mouse Caspase-1 ELISA Kit (Colorimetric)
(2)

Potent and selective inhibitor of caspases 1, 5 and 4

Purity: ≥95% (HPLC)
Potent and selective inhibitor of caspases 1, 5 and 4
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