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BDNF Products

BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.

34 results for "BDNF" in Products

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BDNF Products

BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.

34 results for "BDNF" in Products

BA

An economically priced, CHO-expressed version is now available.

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Detects free and Trk-bound BDNF

Simple Plex Cartridge Kit containing BDNF for use with Human Plasma/Serum. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Activates TrkB and p75 receptors

ELISA

Recombinant Monoclonal Antibody.

CyTOF-ready, ICFlow
CyTOF-ready, ICFlow
ICFlow
WB, IHC
ELISA
Catalog #: 898072

Control for use with Human BDNF Simple Plex Cartridge Kit

Catalog #: IC2481T
ICFlow
Catalog #: MAB3175
IHC
ICFlow
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