BDNF Products
BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer.
It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.
Products:
175 results for "BDNF" in Products
175 results for "BDNF" in Products
BDNF Products
BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer.
It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.
Products:
| Source: | CHO |
| Accession #: | P23560.1 |
| Applications: | BA |
| Sensitivity: | 20 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Heparin Plasma, Citrate Plasma) |
Detects free and Trk-bound BDNF
| Sensitivity: | 1.35 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Platelet-poor EDTA Plasma, Heparin Plasma, Platelet-poor Heparin Plasma, Urine, Human Milk) |
Simple Plex Human BDNF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Biotinylated
| Source: | CHO |
| Accession #: | P23560.1 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat, Zebrafish, Fish - Danio rerio (Zebrafish) |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BDNF Antibody [NB100-98682]](https://resources.bio-techne.com/images/products/BDNF-Antibody-Western-Blot-NB100-98682-img0010.jpg "Western Blot: BDNF Antibody [NB100-98682]")
| Assay Range: | 23.4 - 1,500 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | P23560.1 |
| Applications: | BA |
Activates TrkB and p75 receptors
| Purity: | ≥95% (HPLC) |
Control for use with Human and Non-Human Primate BDNF Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Assay Range: | 78.1 - 5,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #37141 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: BDNF Antibody [NBP1-46750]](https://resources.bio-techne.com/images/products/BDNF-Antibody-Western-Blot-NBP1-46750-img0002.jpg "Western Blot: BDNF Antibody [NBP1-46750]")
| Applications: | ELISA, NULL |
| Source: | E. coli |
| Accession #: | P23560.1 |
| Applications: | BA |
Simple Plex Non-Human Primate BDNF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
For use with catalog number DBNT00
| Applications: | Ctrl |
| Source: | E. coli |
| Accession #: | P23560.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Chicken IgY Polyclonal |
| Applications: | CyTOF-ready, ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #37141 |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat, Zebrafish |
| Details: | Rabbit IgG Monoclonal Clone #SJ12-09 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BDNF Antibody (SJ12-09) [NBP2-67410]](https://resources.bio-techne.com/images/products/BDNF-Antibody-SJ12-09-Western-Blot-NBP2-67410-img0005.jpg "Western Blot: BDNF Antibody (SJ12-09) [NBP2-67410]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Immunohistochemistry: BDNF Antibody - Azide and BSA Free [NB100-98683]](https://resources.bio-techne.com/images/products/BDNF-Antibody-Immunohistochemistry-NB100-98683-img0010.jpg "Immunohistochemistry: BDNF Antibody - Azide and BSA Free [NB100-98683]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #37129R |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #35909 |
| Applications: | CyTOF-ready, ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #35909 |
| Applications: | ICFlow |
