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BDNF Products
BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.
34 results for "BDNF" in Products
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BDNF Products
BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.
34 results for "BDNF" in Products
Catalog #:
11166-BD
BA
| Source : | CHO |
| Accession # : | P23560.1 |
| Applications : | Bioactivity |
ELISA
| Assay Range : | 78.1 - 5,000 pg/mL |
| Applications : | ELISA |
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
BA, Bind
An economically priced, CHO-expressed version is now available.
| Source : | Sf 21 (baculovirus) |
| Accession # : | P23560 |
| Applications : | Binding Activity, Bioactivity |
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ELISA
| Sensitivity : | 20 pg/mL |
| Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Heparin Plasma, Citrate Plasma) |
| Applications : | ELISA |
ELISA
Detects free and Trk-bound BDNF
| Sensitivity : | 1.35 pg/mL |
| Assay Range : | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Platelet-poor EDTA Plasma, Heparin Plasma, Platelet-poor Heparin Plasma, Urine, Human Milk) |
| Applications : | ELISA |
ELISA
| Assay Range : | 23.4 - 1,500 pg/mL |
| Applications : | ELISA |
ELISA
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications : | ELISA |
Catalog #:
SPCKB-PS-000389
Simple Plex Cartridge Kit containing BDNF for use with Human Plasma/Serum. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Activates TrkB and p75 receptors
| Purity : | ≥95% (HPLC) |
Catalog #:
MAB848R
ELISA
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #37129R |
| Applications : | ELISA, ELISA Capture |
CyTOF-ready, ICFlow
| Clonality : | Polyclonal |
| Host : | Chicken IgY |
| Applications : | CyTOF-ready, Flow Cytometry |
Catalog #:
BAM648
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #37141 |
| Applications : | ELISA Detection |
WB, ELISA
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #37141 |
| Applications : | ELISA, Western Blot |
CyTOF-ready, ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #35909 |
| Applications : | CyTOF-ready, Flow Cytometry |
WB, IHC
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #35928 |
| Applications : | Immunohistochemistry, Western Blot |
Catalog #:
IC2481A
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #35909 |
| Applications : | Flow Cytometry |
Catalog #:
MAB31751
WB, IHC
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #584412 |
| Applications : | Immunohistochemistry, Western Blot |
Catalog #:
MAB31752
ELISA
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #584431 |
| Applications : | ELISA |
Catalog #:
IC2481T
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #35909 |
| Applications : | Flow Cytometry |
Catalog #:
MAB3175
IHC
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #584421 |
| Applications : | Immunohistochemistry |
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #35909 |
| Applications : | Flow Cytometry |
